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Sean C. MacKenzie Turner

Novel Transient Receptor Potential Vanilloid 1 Receptor Antagonists for the Treatment of Pain: Structure−Activity Relationships for Ureas with Quinoline, Isoquinoline, Quinazoline, Phthalazine, Quinoxaline, and Cinnoline Moieties
2005 · Arthur Gomtsyan, Erol K. Bayburt, et al. · Journal of Medicinal Chemistry · 165
Use of "off-label" and unlicensed drugs in paediatric intensive care unit
1996 · Sean Turner, Andrea Gill, et al. · The Lancet · 129
Setting International Standards in Analyzing Patient-Reported Outcomes and Quality of Life Endpoints in Cancer Clinical Trials-Innovative Medicines Initiative (SISAQOL-IMI): stakeholder views, objectives, and procedures
2023 · Madeline Pe, Ahu Alanya, et al. · The Lancet Oncology · 68
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Discovery of A-971432, An Orally Bioavailable Selective Sphingosine-1-Phosphate Receptor 5 (S1P5) Agonist for the Potential Treatment of Neurodegenerative Disorders
2015 · Adrian D. Hobson, Christopher M. Harris, et al. · Journal of Medicinal Chemistry · 49
Synthesis and Structure−Activity Relationships of a Novel Series of 2,3,5,6,7,9-Hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-Dioxide KATP Channel Openers: Discovery of (−)-(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9- hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-Dioxide (A-278637), a Potent KATP Opener That Selectively Inhibits Spontaneous Bladder Contractions
2004 · William A. Carroll, Robert J. Altenbach, et al. · Journal of Medicinal Chemistry · 44
Enantiospecific Synthesis of Annulated Nicotine Analogues from d - and l -Glutamic Acid. Pyridotropanes
2000 · Sean C. Turner, Hongbin Zhai, et al. · The Journal of Organic Chemistry · 40
Synthesis and Structure−Activity Relationships of a Novel Series of Tricyclic Dihydropyridine-Based KATP Openers That Potently Inhibit Bladder Contractions in Vitro
2004 · William A. Carroll, Konstantinos A. Agrios, et al. · Journal of Medicinal Chemistry · 36
Conformationally Constrained Nicotines. 1-Pyridinyl-7-azabicyclo[2.2.1]heptane and 1-Pyridinyl-8-azabicyclo[3.2.1]octane Analogues
1999 · Ying-zi Xu, Jaesung Choi, et al. · The Journal of Organic Chemistry · 35
α-Methylation at benzylic fragment of N-aryl-N′-benzyl ureas provides TRPV1 antagonists with better pharmacokinetic properties and higher efficacy in inflammatory pain model
2007 · Arthur Gomtsyan, Erol K. Bayburt, et al. · Bioorganic & Medicinal Chemistry Letters · 33
Unregistered and Off‐Label Drug Use in Paediatric Inpatients
1999 · Sean Turner · Journal of Pharmacy Practice and Research · 31
Structure–activity studies of a novel series of 5,6-fused heteroaromatic ureas as TRPV1 antagonists
2006 · Irene Drizin, Arthur Gomtsyan, et al. · Bioorganic & Medicinal Chemistry · 30
Trends in incidence, prevalence, and survival of breast cancer in the United Kingdom from 2000 to 2021
2024 · Nicola L. Barclay, Edward Burn, et al. · Scientific Reports · 28
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In Vitro Structure−Activity Relationship and In Vivo Characterization of 1-(Aryl)-3-(4-(amino)benzyl)urea Transient Receptor Potential Vanilloid 1 Antagonists
2007 · Richard J. Perner, Stanley DiDomenico, et al. · Journal of Medicinal Chemistry · 27
Enantiospecific Synthesis of Annulated Nicotine Analogues from d -Glutamic Acid. 7-Azabicyclo[2.2.1]heptano[2.3-c]pyridines
2001 · Joseph R. Lennox, Sean C. Turner, et al. · The Journal of Organic Chemistry · 27
Microwave-Assisted Synthesis of Novel (5-Nitropyridin-2-yl)alkyl and (5-Nitropyridin-3-yl)alkyl Carbamates
2009 · Christophe Henry, Andreas Haupt, et al. · The Journal of Organic Chemistry · 24
The discovery of a new class of large-conductance Ca2+-activated K+ channel opener targeted for overactive bladder: synthesis and structure–activity relationships of 2-amino-4-azaindoles
2003 · Sean C. Turner, William A. Carroll, et al. · Bioorganic & Medicinal Chemistry Letters · 24
The synthesis of substituted pyrrolidines by a Samarium (II) iodide-mediated ring closure. Part 1
1994 · Jack E. Baldwin, Sean C. MacKenzie Turner, et al. · Tetrahedron · 23
eTRANSAFE: data science to empower translational safety assessment
2023 · Ferran Sanz, François Pognan, et al. · Nature Reviews Drug Discovery · 22
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Quantitative systems toxicology: modelling to mechanistically understand and predict drug safety
2025 · Christopher E. Goldring, Giusy Russomanno, et al. · Nature Reviews Drug Discovery · 21
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The synthesis of substituted pyrrolidines by a samarium (II) iodide mediated ring closure. Part 2
1994 · Jack E. Baldwin, Sean C. MacKenzie Turner, et al. · Tetrahedron · 19
Anticonvulsant effects of structurally diverse GABAB positive allosteric modulators in the DBA/2J audiogenic seizure test: Comparison to baclofen and utility as a pharmacodynamic screening model
2015 · Jordan W. Brown, Achim Moeller, et al. · Neuropharmacology · 18
A new class of histamine H3-Receptor antagonists: synthesis and structure–Activity relationships of 7,8,9,10-Tetrahydro-6H-cyclohepta[b]quinolines
2003 · Sean C. Turner, Timothy A. Esbenshade, et al. · Bioorganic & Medicinal Chemistry Letters · 17
Unlicensed and Off-label Drug Use in Australia
2000 · Sean Turner · Paediatric and Perinatal Drug Therapy · 14
Cost Implications of Using Inhaled Nitric Oxide Compared with Epoprostenol for Pulmonary Hypertension
1995 · Andy J Petros, Sean C Turner, et al. · Journal of Pharmacy Technology · 14
Enantioselective Synthesis of Novel Functionalised Prolines via [3 + 2] Cycloadditions of a Chiral Azomethine Ylid
1994 · Jack E. Baldwin, Sean C. MacKenzie Turner, et al. · Synlett · 14
Works count: 66
Citation count: 1,062
H-index: 19
I10-index: 27
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