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Dennis A. Ruff

Effects of LX4211, a Dual SGLT1/SGLT2 Inhibitor, Plus Sitagliptin on Postprandial Active GLP-1 and Glycemic Control in Type 2 Diabetes
2013 · Brian Zambrowicz, Zhi-Ming Ding, et al. · Clinical Therapeutics · 79
Add-On Treatment With Zilebesiran for Inadequately Controlled Hypertension: The KARDIA-2 Randomized Clinical Trial
2025 · Akshay S. Desai, Adam D. Karns, et al. · JAMA · 70
Effects of LX4211, a Dual Sodium-Dependent Glucose Cotransporters 1 and 2 Inhibitor, on Postprandial Glucose, Insulin, Glucagon-like Peptide 1, and Peptide Tyrosine Tyrosine in a Dose-Timing Study in Healthy Subjects
2013 · Brian Zambrowicz, Ike Ogbaa, et al. · Clinical Therapeutics · 64
Pharmacokinetics of Lumiracoxib in Plasma and Synovial Fluid
2004 · Graham Scott, Christiane Rordorf, et al. · Clinical Pharmacokinetics · 59
A randomized, placebo‐controlled, single and multiple dose study of intravenous thymosin β4 in healthy volunteers
2010 · Dennis Ruff, David Crockford, et al. · Annals of the New York Academy of Sciences · 48
Comparative effects of combination drug therapy regimens commencing with either losartan potassium, an angiotensin II receptor antagonist, or enalapril maleate for the treatment of severe hypertension
1996 · Dennis Ruff, Lisa P. Gazdick, et al. · Journal of Hypertension · 35
A Randomized, Placebo‐Controlled, Multiple‐Ascending‐Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Soluble Guanylate Cyclase Stimulator Praliciguat in Healthy Subjects
2018 · John P. Hanrahan, James D. Wakefield, et al. · Clinical Pharmacology in Drug Development · 33
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One-Year Study of Felodipine or Placebo for Stage 1 Isolated Systolic Hypertension
2001 · Henry R. Black, William J. Elliott, et al. · Hypertension · 33
A First‐in‐Human Clinical Study With TRV734, an Orally Bioavailable G‐Protein–Biased Ligand at the μ‐Opioid Receptor
2019 · Ian E. James, Franck Skobieranda, et al. · Clinical Pharmacology in Drug Development · 26
Effective dose range of Candesartan cilexetil for systemic hypertension
1999 · T.Phillip Bell, Vincent DeQuattro, et al. · The American Journal of Cardiology · 16
Absence of an effect of T89 on the steady-state pharmacokinetics and pharmacodynamics of warfarin in healthy volunteers: The Journal of Clinical Pharmacology
2013 · Ping Wang, He Sun, et al. · The Journal of Clinical Pharmacology · 12
Two‐Part Phase 1 Multiple‐Ascending‐Dose Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of TRV734 in Healthy Adults
2021 · Kimberly A. Ramos, Ian E. James, et al. · Clinical Pharmacology in Drug Development · 9
Does GLP-1 suppress its own basal secretion?
2015 · Dariush Elahi, Dennis A. Ruff, et al. · Endocrine Research · 9
Efficacy and tolerability of tasosartan, a novel angiotensin II receptor blocker: Results from a 10-week, double-blind, placebo-controlled, dose-titration study
1999 · Joel M. Neutel, Vardaman Buckalew, et al. · American Heart Journal · 9
Multiple-Ascending-Dose Study of the Soluble Guanylate Cyclase Stimulator, IW-1701, in Healthy Subjects
2017 · Robert S. Mittleman, Phebe Wilson, et al. · Blood · 7
A phase I randomized, double‐blind , single subcutaneous dose escalation study to determine the safety, tolerability, and pharmacokinetics of rezafungin in healthy adult subjects
2022 · Kenan Gu, Dennis Ruff, et al. · Clinical and Translational Science · 6
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First-in-human Single-ascending-dose Study of Iw-1973, a New Soluble Guanylate Cyclase Stimulator
2016 · John Hanrahan, Albert T. Profy, et al. · Journal of the American College of Cardiology · 4
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Pseudomembranous Colitis Following Low Dose Trimethoprim-Sulfamethoxazole
1985 · Dennis Ruff, John Jaffe, et al. · The Journal of Urology · 4
Rapid Dose Escalation Study of Praliciguat, a Soluble Guanylate Cyclase Stimulator, in Patients with Diabetes and Hypertension
2018 · JOHN P. HANRAHAN, JAMES D. WAKEFIELD, et al. · Diabetes · 2
Abstract P493: Multiple-ascending-dose Study of IW-1973, a Soluble Guanylate Cyclase Stimulator
2017 · John Hanrahan, James Wakefield, et al. · Hypertension · 2
Concomitant Treatment With Aleglitazar Does Not Change the Effects on Renal Function Induced by Aspirin
2012 · Carolina Pellanda, Dennis Ruff, et al. · Journal of the American College of Cardiology
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Works count: 21
Citation count: 527
H-index: 11
I10-index: 11
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