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Joanna J. Zheng

Observed names: Joanna J Zheng, Joanna Zheng, Zheng, Joanna J.
OpenAlex ID: A5113215415
Screening and Identification of GSH-Trapped Reactive Metabolites Using Hybrid Triple Quadruple Linear Ion Trap Mass Spectrometry
2007 · Joanna Zheng, Li Ma, et al. · Chemical Research in Toxicology · 120
Discovery of Milvexian, a High-Affinity, Orally Bioavailable Inhibitor of Factor XIa in Clinical Studies for Antithrombotic Therapy
2021 · Andrew K. Dilger, Kumar B. Pabbisetty, et al. · Journal of Medicinal Chemistry · 116
P2Y6 Receptor Potentiates Pro-Inflammatory Responses in Macrophages and Exhibits Differential Roles in Atherosclerotic Lesion Development
2014 · Ricardo A. Garcia, Mujing Yan, et al. · PLoS ONE · 79
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Conformationally Constrained ortho-Anilino Diaryl Ureas: Discovery of 1-(2-(1′-Neopentylspiro[indoline-3,4′-piperidine]-1-yl)phenyl)-3-(4-(trifluoromethoxy)phenyl)urea, a Potent, Selective, and Bioavailable P2Y1 Antagonist
2013 · Jennifer X. Qiao, Tammy C. Wang, et al. · Journal of Medicinal Chemistry · 73
Application and Challenges in Using LC–MS Assays for Absolute Quantitative Analysis of Therapeutic Proteins in Drug Discovery
2014 · Joanna Zheng, John Mehl, et al. · Bioanalysis · 60
Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212)
2017 · Donald J. P. Pinto, Michael J. Orwat, et al. · Journal of Medicinal Chemistry · 58
Structure-Based Design of Macrocyclic Factor XIa Inhibitors: Discovery of the Macrocyclic Amide Linker
2017 · James R. Corte, Tianan Fang, et al. · Journal of Medicinal Chemistry · 42
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In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties
2009 · Gang Luo, Stephen Johnson, et al. · Drug Metabolism and Disposition · 37
Comparison of SPE and fast LC to eliminate mass spectrometric matrix effects from microsomal incubation products
2002 · Joanna J. Zheng, Eric D. Lynch, et al. · Journal of Pharmaceutical and Biomedical Analysis · 35
Novel phenylalanine derived diamides as Factor XIa inhibitors
2015 · Leon M. Smith, Michael J. Orwat, et al. · Bioorganic & Medicinal Chemistry Letters · 31
Potent, Orally Bioavailable, and Efficacious Macrocyclic Inhibitors of Factor XIa. Discovery of Pyridine-Based Macrocycles Possessing Phenylazole Carboxamide P1 Groups
2019 · James R. Corte, Donald J. P. Pinto, et al. · Journal of Medicinal Chemistry · 30
Discovery of a High Affinity, Orally Bioavailable Macrocyclic FXIa Inhibitor with Antithrombotic Activity in Preclinical Species
2020 · Wu Yang, Yufeng Wang, et al. · Journal of Medicinal Chemistry · 27
Discovery of a Potent Parenterally Administered Factor XIa Inhibitor with Hydroxyquinolin-2(1H)-one as the P2′ Moiety
2015 · Zilun Hu, Pancras C. Wong, et al. · ACS Medicinal Chemistry Letters · 27
Orally bioavailable pyridine and pyrimidine-based Factor XIa inhibitors: Discovery of the methyl N-phenyl carbamate P2 prime group
2016 · James R. Corte, Tianan Fang, et al. · Bioorganic & Medicinal Chemistry · 24
2-Aminothiazole based P2Y1 antagonists as novel antiplatelet agents
2013 · Zulan Pi, James Sutton, et al. · Bioorganic & Medicinal Chemistry Letters · 24
Macrocyclic inhibitors of Factor XIa: Discovery of alkyl-substituted macrocyclic amide linkers with improved potency
2017 · James R. Corte, Wu Yang, et al. · Bioorganic & Medicinal Chemistry Letters · 23
Discovery of diarylurea P2Y1 antagonists with improved aqueous solubility
2013 · Tammy C. Wang, Jennifer X. Qiao, et al. · Bioorganic & Medicinal Chemistry Letters · 21
The utility of stable isotope labeled (SIL) analogues in the bioanalysis of endogenous compounds by LC-MS applied to the study of bile acids in a metabolomics assay
2016 · Joanna J. Zheng, Eric E. Shields, et al. · Analytical Biochemistry · 18
Structure based design of macrocyclic factor XIa inhibitors: Discovery of cyclic P1 linker moieties with improved oral bioavailability
2019 · Charles G. Clark, Karen A. Rossi, et al. · Bioorganic & Medicinal Chemistry Letters · 15
An Analysis of Antimicrobial Resistance of Clinical Pathogens from Historical Samples for Six Countries
2019 · Karen Li, Joanna Zheng, et al. · Processes · 11
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Bioactivation of coumarin in rat olfactory mucosal microsomes: Detection of protein covalent binding and identification of reactive intermediates through analysis of glutathione adducts
2009 · Xiaoliang Zhuo, Weiping Zhao, et al. · Chemico-Biological Interactions · 11
Potent P2Y1 urea antagonists bearing various cyclic amine scaffolds
2013 · Réjean Ruel, Alexandre L’Heureux, et al. · Bioorganic & Medicinal Chemistry Letters · 10
Orally bioavailable amine-linked macrocyclic inhibitors of factor XIa
2020 · Tianan Fang, James R. Corte, et al. · Bioorganic & Medicinal Chemistry Letters · 8
CCDC 2074385: Experimental Crystal Structure Determination
2021 · Dilger, Andrew K., Pabbisetty, Kumar B., et al. · The Cambridge Structural Database
CCDC 1568523: Experimental Crystal Structure Determination
2018 · Pinto, Donald J. P., Orwat, Michael J., et al. · The Cambridge Structural Database
Works count: 27
Citation count: 900
H-index: 18
I10-index: 22
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