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Zhao‐Kui Wan

Observed names: Wan, Zhao-Kui, Z. WAN, Z.-K. Wan, Z.‐K. WAN, Z.‐K. Wan, Zhao-Kui Wan, Zhao-kui Wan, Zhaokui Wan
OpenAlex ID: A5113492264
Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( S )-2,2-Difluorocyclopropyl)((1 R ,5 S )-3-(2-((1-methyl-1 H -pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841)
2018 · Andrew Fensome, Catherine M. Ambler, et al. · Journal of Medicinal Chemistry · 190
Structure-Based Optimization of Protein Tyrosine Phosphatase 1B Inhibitors: From the Active Site to the Second Phosphotyrosine Binding Site
2007 · Douglas P. Wilson, Zhao-Kui Wan, et al. · Journal of Medicinal Chemistry · 162
The Scope and Mechanism of Phosphonium-Mediated SNAr Reactions in Heterocyclic Amides and Ureas
2007 · Zhao-Kui Wan, Sumrit Wacharasindhu, et al. · The Journal of Organic Chemistry · 119
Asymmetric Ni(II)/Cr(II)-Mediated Coupling Reaction: Catalytic Process
2002 · Hyeong-wook Choi, Katsumasa Nakajima, et al. · Organic Letters · 117
Comparative performance evaluation and systematic screening of solvents in a range of Grignard reactions
2013 · Asha Kadam, Mylinh Nguyen, et al. · Green Chemistry · 109
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Asymmetric Ni(II)/Cr(II)-Mediated Coupling Reaction: Stoichiometric Process
2002 · Zhao-Kui Wan, Hyeong-wook Choi, et al. · Organic Letters · 90
Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors
2005 · A.F. Moretto, S.J. Kirincich, et al. · Bioorganic & Medicinal Chemistry · 80
An Efficient Direct Amination of Cyclic Amides and Cyclic Ureas
2006 · Zhao-Kui Wan, Sumrit Wacharasindhu, et al. · Organic Letters · 77
Synthetic studies on the marine natural product halichondrins
2003 · Hyeong-wook Choi, Damtew Demeke, et al. · Pure and Applied Chemistry · 72
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Oxidative Palladium Catalysis in SNAr Reactions Leading to Heteroaryl Ethers from Pyridotriazol-1-yloxy Heterocycles with Aryl Boronic Acids
2009 · Sumrit Wacharasindhu, Sujata Bardhan, et al. · Journal of the American Chemical Society · 68
Efficacious 11β-Hydroxysteroid Dehydrogenase Type I Inhibitors in the Diet-Induced Obesity Mouse Model
2009 · Zhao-Kui Wan, Eva Chenail, et al. · Journal of Medicinal Chemistry · 66
A Highly Facile and Efficient One-Step Synthesis of N6-Adenosine and N6-2‘-Deoxyadenosine Derivatives
2005 · Zhao-Kui Wan, Eva Binnun, et al. · Organic Letters · 66
Intramolecular Inverse-Electron-Demand Diels−Alder Reactions of Imidazoles with 1,2,4-Triazines: A New Route to 1,2,3,4-Tetrahydro-1,5-naphthyridines and Related Heterocycles
2004 · Brian R. Lahue, Sie-Mun Lo, et al. · The Journal of Organic Chemistry · 65
Assessing IRAK4 Functions in ABC DLBCL by IRAK4 Kinase Inhibition and Protein Degradation
2020 · Jing Zhang, Liqiang Fu, et al. · Cell chemical biology · 63
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Efficient Phosphonium-Mediated Synthesis of 2-Amino-1,3,4-oxadiazoles
2008 · Christopher G. Levins, Zhao-Kui Wan · Organic Letters · 57
Monocyclic thiophenes as protein tyrosine phosphatase 1B inhibitors: Capturing interactions with Asp48
2006 · Zhao-Kui Wan, Jinbo Lee, et al. · Bioorganic & Medicinal Chemistry Letters · 57
Preparation of α-Haloacrylate Derivatives via Dimethyl Sulfoxide-Mediated Selective Dehydrohalogenation
2007 · Wei Li, Jianchang Li, et al. · Organic Letters · 45
Chapter 6.2 Six-membered ring systems: Diazines and benzo derivatives
2002 · Grace H.C. Woo, John K. Snyder, et al. · Progress in heterocyclic chemistry · 45
Imidazotriazines: Spleen Tyrosine Kinase (Syk) Inhibitors Identified by Free‐Energy Perturbation (FEP)
2015 · Frank Lovering, Cristina Aevazelis, et al. · ChemMedChem · 44
Probing acid replacements of thiophene PTP1B inhibitors
2007 · Zhao-Kui Wan, Bruce Follows, et al. · Bioorganic & Medicinal Chemistry Letters · 44
Dienophilicity of imidazole in inverse electron demand Diels–Alder reactions: cycloadditions with 1,2,4,5-tetrazines and the structure of zarzissine
2001 · Zhao-Kui Wan, Grace H.C. Woo, et al. · Tetrahedron · 44
Synthesis of Potent and Orally Efficacious 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor HSD-016
2011 · Zhao-Kui Wan, Eva Chenail, et al. · The Journal of Organic Chemistry · 35
Piperazine Sulfonamides as Potent, Selective, and Orally Available 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors with Efficacy in the Rat Cortisone-Induced Hyperinsulinemia Model
2008 · Jason Xiang, Zhao-Kui Wan, et al. · Journal of Medicinal Chemistry · 32
Dienophilicity of Imidazole in Inverse Electron Demand Diels−Alder Reactions. 4. Intermolecular Reactions with 1,2,4-Triazines
2003 · Brian R. Lahue, Zhao-Kui Wan, et al. · The Journal of Organic Chemistry · 32
Aminopyrazole Carboxamide Bruton’s Tyrosine Kinase Inhibitors. Irreversible to Reversible Covalent Reactive Group Tuning
2018 · Mark E. Schnute, Stephen E. Benoit, et al. · ACS Medicinal Chemistry Letters · 30
Works count: 63
Citation count: 2,027
H-index: 26
I10-index: 35
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