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Baomin Xin

Observed names: B. Xin, Xin, Baomin
OpenAlex ID: A5113520459
Discovery of 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro- 1H-pyrazolo[3,4-c]pyridine-3-carboxamide (Apixaban, BMS-562247), a Highly Potent, Selective, Efficacious, and Orally Bioavailable Inhibitor of Blood Coagulation Factor Xa
2007 · Donald J. P. Pinto, Michael J. Orwat, et al. · Journal of Medicinal Chemistry · 413
Screening and Identification of GSH-Trapped Reactive Metabolites Using Hybrid Triple Quadruple Linear Ion Trap Mass Spectrometry
2007 · Joanna Zheng, Li Ma, et al. · Chemical Research in Toxicology · 120
Monolithic columns containing sol–gel bonded octadecylsilica for capillary electrochromatography
1999 · Qinglin Tang, Baomin Xin, et al. · Journal of Chromatography A · 117
Fast ultrahigh-pressure liquid chromatography: On-column UV and time-of-flight mass spectrometric detection
1999 · J. Andreas Lippert, Baomin Xin, et al. · Journal of Microcolumn Separations · 98
Preclinical pharmacokinetics and pharmacodynamics of apixaban, a potent and selective factor Xa inhibitor
2011 · Kan He, Joseph M. Luettgen, et al. · European Journal of Drug Metabolism and Pharmacokinetics · 94
Application and Challenges in Using LC–MS Assays for Absolute Quantitative Analysis of Therapeutic Proteins in Drug Discovery
2014 · Joanna Zheng, John Mehl, et al. · Bioanalysis · 60
Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212)
2017 · Donald J. P. Pinto, Michael J. Orwat, et al. · Journal of Medicinal Chemistry · 58
Preclinical Pharmacokinetic and Metabolism of Apixaban, a Potent and Selective Factor Xa Inhibitor.
2006 · Kan He, Bing He, et al. · Blood · 49
Design and evaluation of a new capillary electrochromatography system
1999 · Baomin Xin, Milton L. Lee · Electrophoresis · 44
Development of a quantitative LC–MS/MS analytical method coupled with turbulent flow chromatography for digoxin for the in vitro P-gp inhibition assay
2007 · James Smalley, Anthony M. Marino, et al. · Journal of Chromatography B · 40
Development of an on-line extraction turbulent flow chromatography tandem mass spectrometry method for cassette analysis of Caco-2 cell based bi-directional assay samples
2005 · James Smalley, Pathanjali Kadiyala, et al. · Journal of Chromatography B · 40
In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties
2009 · Gang Luo, Stephen Johnson, et al. · Drug Metabolism and Disposition · 37
Design of a Time-of-Flight Mass Spectrometer as a Detector for Capillary Electrophoresis
1997 · Iulia M. Lazar, Baomin Xin, et al. · Analytical Chemistry · 36
Effect of the Direct Factor Xa Inhibitor Apixaban in Rat Models of Thrombosis and Hemostasis
2010 · William A Schumacher, Jeffrey S Bostwick, et al. · Journal of Cardiovascular Pharmacology · 33
Novel phenylalanine derived diamides as Factor XIa inhibitors
2015 · Leon M. Smith, Michael J. Orwat, et al. · Bioorganic & Medicinal Chemistry Letters · 31
BMS-593214, an active site-directed factor VIIa inhibitor: Enzyme kinetics, antithrombotic and antihaemostatic studies
2010 · Joseph Luettgen, Alan Rendina, et al. · Thrombosis and Haemostasis · 31
N-in-1 Dosing Pharmacokinetics in Drug Discovery: Experience, Theoretical and Practical Considerations
2007 · Kan He, Mingxin Qian, et al. · Journal of Pharmaceutical Sciences · 29
Voltage programming in capillary electrochromatography
1999 · Baomin Xin, Milton L. Lee · Journal of Microcolumn Separations · 26
Increasing high‐throughput Discovery bioanalysis using automated selected reaction monitoring compound optimization, ultra‐high‐pressure liquid chromatography, and single‐step sample preparation workflows
2009 · James Smalley, Baomin Xin, et al. · Rapid Communications in Mass Spectrometry · 25
Bioanalytical strategies for developing highly sensitive liquid chromatography/tandem mass spectrometry based methods for the peptide GLP‐1 agonists in support of discovery PK/PD studies
2011 · Hongwei Zhang, Baomin Xin, et al. · Rapid Communications in Mass Spectrometry · 22
Optimization of Exactive Orbitrap™ Acquisition Parameters for Quantitative Bioanalysis
2011 · Richard L Wong, Baomin Xin, et al. · Bioanalysis · 21
Metabolism, pharmacokinetics and pharmacodynamics of the factor Xa inhibitor apixaban in rabbits
2009 · Donglu Zhang, Kan He, et al. · Journal of Thrombosis and Thrombolysis · 20
The utility of stable isotope labeled (SIL) analogues in the bioanalysis of endogenous compounds by LC-MS applied to the study of bile acids in a metabolomics assay
2016 · Joanna J. Zheng, Eric E. Shields, et al. · Analytical Biochemistry · 18
Highly efficacious factor Xa inhibitors containing α-substituted phenylcycloalkyl P4 moieties
2008 · Jennifer X. Qiao, Sarah R. King, et al. · Bioorganic & Medicinal Chemistry Letters · 17
Enantiopure five-membered cyclicdiamine derivatives as potent and selective inhibitors of factor Xa. Improving in vitro metabolic stability via core modifications
2007 · Jennifer X. Qiao, Tammy C. Wang, et al. · Bioorganic & Medicinal Chemistry Letters · 17
Works count: 32
Citation count: 1,555
H-index: 21
I10-index: 28
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