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Rafael J. Apitz-Castro

Observed names: R Apitz-Castro, R Apitz‐Castro, R. APITZ‐CASTRO, R. Apitz-Castro, R. Apitz-Cȧstro, R. Apitz-castro, R. Apitz‐Castro, R.C. Apitz-Castro, Rafael Apitz-Castro, Rafael Apitz‐Castro, Rafael. Apitz-Castro, Raphael Apitz-Castro
Observed institutions: Uppsala University, Universidade Estadual de Maringá, Centre National de la Recherche Scientifique, State University of New York, Academia Nacional de Medicina, Max Planck Society, Inserm, Universidad de Los Andes, Universidad de Oriente, Instituto Venezolano de Investigaciones Científicas, Utrecht University, University of Washington, Universidad de Los Andes, Maastricht University Medical Centre, University at Albany, State University of New York, Hôpital Lariboisière, Indiana University Bloomington, Synapse (Netherlands), Centro Médico Docente La Trinidad, Academia Nacional de Medicina Venezuela, University of Southampton, University of Bergen, The Ohio State University, Indiana University, Temple University, University of Delaware
OpenAlex ID: A5113544495
The chemistry of alkyl thiosulfinate esters. 9. Antithrombotic organosulfur compounds from garlic: structural, mechanistic, and synthetic studies
1986 · Eric. Block, Saleem. Ahmad, et al. · Journal of the American Chemical Society · 321
The chemistry of alkyl thiosulfate esters. 8. (E,Z)-Ajoene: a potent antithrombotic agent from garlic
1984 · Eric Block, Saleem Ahmad, et al. · Journal of the American Chemical Society · 246
Effects of garlic extract and of three pure components isolated from it on human platelet aggregation, arachidonate metabolism, release reaction and platelet ultrastructure
1983 · R. Apitz-Cȧstro, S. Cabrera, et al. · Thrombosis Research · 199
Tight binding inhibitors of 85-kDa phospholipase A2 but not 14-kDa phospholipase A2 inhibit release of free arachidonate in thrombin-stimulated human platelets.
1994 · F. Bartoli, H.K. Lin, et al. · Journal of Biological Chemistry · 182
Identification of the Phosphorylation Sites of Cytosolic Phospholipase A2 in Agonist-stimulated Human Platelets and HeLa Cells
1998 · Angelika G. Börsch-Haubold, Fulvia Bartoli, et al. · Journal of Biological Chemistry · 158
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Interaction of phospholipase A2 and phospholipid bilayers
1982 · Mahendra K. Jain, Maarten R. Egmond, et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 141
Origin of the latency phase during the action of phospholipase A2 on unmodified phosphatidylcholine vesicles
1982 · Rafael Apitz-Castro, Mahendra K. Jain, et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 134
Whole-Blood Thrombin Generation Monitored with a Calibrated Automated Thrombogram-Based Assay
2012 · Marisa Ninivaggi, Rafael Apitz-Castro, et al. · Clinical Chemistry · 131
Ajoene, the antiplatelet principle of garlic, synergistically potentiates the antiaggregatory action of prostacyclin, forskolin, indomethacin and dypiridamole on human platelets
1986 · Rafael Apitz-Castro, Javier Escalante, et al. · Thrombosis Research · 106
Trifluoromethyl ketones and methyl fluorophosphonates as inhibitors of group IV and VI phospholipases A2: structure-function studies with vesicle, micelle, and membrane assays1This paper is dedicated to the memory of Prof. H.M. Verheij.1
1999 · Farideh Ghomashchi, Richard Loo, et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 78
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Effect of ajoene, the major antiplatelet compound from garlic, on platelet thrombus formation
1992 · Rafael Apitz-Castro, Juan J. Badimon, et al. · Thrombosis Research · 77
Ajoene, el principal compuesto activo derivado del ajo (Allium sativum), un nuevo agente antifúngico
2006 · Eliades Ledezma, Rafael Apitz-Castro · Revista Iberoamericana de Micología · 75
Inhibition of phosphatidylcholine biosynthesis and cell proliferation in trypanosomacruzi by ajoene, an antiplatelet compound isolated from garlic
1993 · Julio A. Urbina, Edgar Marchan, et al. · Biochemical Pharmacology · 67
Membrane-Bound Plasma Platelet Activating Factor Acetylhydrolase Acts on Substrate in the Aqueous Phase
1999 · Jung-Hyun Min, Mahendra K. Jain, et al. · Biochemistry · 66
The molecular basis of the antiplatelet action of ajoene: Direct interaction with the fibrinogen receptor
1986 · Rafael Apitz-Castro, Eliades Ledezma, et al. · Biochemical and Biophysical Research Communications · 61
Isolation of homogeneous phospholipase A2 from human platelets
1979 · Rafael J. Apitz-Castro, Manuel A. Mas, et al. · Biochemical and Biophysical Research Communications · 60
Inhibition of growth of the dimorphic fungus Paracoccidioides brasiliensis by ajoene
1989 · G San-Blas, F San-Blas, et al. · Antimicrobial Agents and Chemotherapy · 57
Ajoene, the antiplatelet compound derived from garlic, specifically inhibits platelet release reaction by affecting the plasma membrane internal microviscosity
1989 · F. Rendu, D. Daveloose, et al. · Biochemical Pharmacology · 57
Ajoene, a garlic compound, inhibits protein prenylation and arterial smooth muscle cell proliferation
2003 · Nicola Ferri, Kohei Yokoyama, et al. · British Journal of Pharmacology · 49
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Efficacy of ajoene in the treatment of tinea pedis: A double-blind and comparative study with terbinafine
2000 · Eliades Ledezma, Katiuska Marcano, et al. · Journal of the American Academy of Dermatology · 48
Plasma total homocysteine quantification: an improvement of the classical high-performance liquid chromatographic method with fluorescence detection of the thiol-SBD derivatives
2002 · Alberto J Garcia, Rafael Apitz-Castro · Journal of Chromatography B · 47
The storage pool deficiency in platelets from humans with the Chédiak‐Higashi syndrome: study of six patients
1985 · Rafael Apitz‐Castro, Maria Rosa Cruz, et al. · British Journal of Haematology · 45
A garlic derivative, ajoene, inhibits platelet deposition on severely damaged vessel wall in an in vivo porcine experimental model
1994 · Rafael Apitz-Castro, Juan Jose Badimon, et al. · Thrombosis Research · 44
Efficacy of ajoene, an organosulphur derived from garlic, in the short‐term therapy of tinea pedis
1996 · E. Ledezma, L. De Sousa, et al. · Mycoses · 42
Concerning the mechanism of the enzymatic and nonenzymatic hydrolysis of nicotinamide nucleotide coenzymes.
1978 · H.G. Bull, J.P. Ferraz, et al. · Journal of Biological Chemistry · 42
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Works count: 101
Citation count: 3,417
H-index: 33
I10-index: 57
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