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Manfred Konrad

The Interaction of Bovine Pancreatic Deoxyribonuclease I and Skeletal Muscle Actin
1980 · Hans Georg MANNHERZ, Roger S. GOODY, et al. · European Journal of Biochemistry · 205
Structure of human dCK suggests strategies to improve anticancer and antiviral therapy
2003 · Elisabetta Sabini, Stephan Ort, et al. · Nature Structural & Molecular Biology · 184
Insights into the phosphoryltransfer mechanism of human thymidylate kinase gained from crystal structures of enzyme complexes along the reaction coordinate
2000 · Nils Ostermann, Ilme Schlichting, et al. · Structure · 110
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Engineered Human tmpk/AZT As a Novel Enzyme/Prodrug Axis for Suicide Gene Therapy
2007 · Takeya Sato, Anton Neschadim, et al. · Molecular Therapy · 105
Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation
1997 · Arnon Lavie, Ingrid R. Vetter, et al. · Nature Structural Biology · 101
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Internal motions in myosin
1979 · Stefan Highsmith, Kazuyuki Akasaka, et al. · Biochemistry · 97
Structural basis for efficient phosphorylation of 3′-azidothymidine monophosphate by Escherichia coli thymidylate kinase
1998 · Arnon Lavie, Nils Ostermann, et al. · Proceedings of the National Academy of Sciences · 88
Elucidation of Human Choline Kinase Crystal Structures in Complex with the Products ADP or Phosphocholine
2006 · Enrico Malito, Nikolina Sekulic, et al. · Journal of Molecular Biology · 79
Micro-optical lens array for fluorescence detection in droplet-based microfluidics
2013 · Jiseok Lim, Philipp Gruner, et al. · Lab on a Chip · 78
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Structural Characterization of the Closed Conformation of Mouse Guanylate Kinase
2002 · Nikolina Sekulic, Ludmila Shuvalova, et al. · Journal of Biological Chemistry · 77
Kinetic and Thermodynamic Properties of the Ternary Complex between F‐actin, Myosin Subfragment 1 and Adenosine 5′‐[β,γ‐imido]triphosphate
1982 · Manfred KONRAD, Roger S. GOODY · European Journal of Biochemistry · 73
Structures of Apo and Product-Bound Human l -Asparaginase: Insights into the Mechanism of Autoproteolysis and Substrate Hydrolysis
2012 · Julian Nomme, Ying Su, et al. · Biochemistry · 69
Crystal Structure of Yeast Thymidylate Kinase Complexed with the Bisubstrate Inhibitor P1-(5‘-Adenosyl) P5-(5‘-Thymidyl) Pentaphosphate (TP5A) at 2.0 Å Resolution: Implications for Catalysis and AZT Activation,
1998 · Arnon Lavie, Manfred Konrad, et al. · Biochemistry · 69
A Point Mutation of Human Nucleoside Diphosphate Kinase A Found in Aggressive Neuroblastoma Affects Protein Folding
1997 · Ioan Lascu, Sabine Schaertl, et al. · Journal of Biological Chemistry · 66
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Melting transitions in biomembranes
2019 · Tea Mužić, Fatma Tounsi, et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 63
Substrate Specificity of Human Nucleoside-diphosphate Kinase Revealed by Transient Kinetic Analysis
1998 · Sabine Schaertl, Manfred Konrad, et al. · Journal of Biological Chemistry · 63
Modifying Human Thymidylate Kinase to Potentiate Azidothymidine Activation
1999 · Ralf Brundiers, Arnon Lavie, et al. · Journal of Biological Chemistry · 62
Structural basis for activation of the therapeutic L-nucleoside analogs 3TC and troxacitabine by human deoxycytidine kinase
2006 · E. Sabini, S. Hazra, et al. · Nucleic Acids Research · 55
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Parallelized ultra-high throughput microfluidic emulsifier for multiplex kinetic assays
2015 · Jiseok Lim, Ouriel Caen, et al. · Biomicrofluidics · 54
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Functional analysis of the guanylate kinase‐like domain in the synapse‐associated protein SAP97
1998 · Sven Kuhlendahl, Oliver Spangenberg, et al. · European Journal of Biochemistry · 54
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Substrate-induced Conformational Changes in Human UMP/CMP Kinase
2004 · Dario Segura-Peña, Nikolina Sekulic, et al. · Journal of Biological Chemistry · 53
Potentiating AZT activation: structures of wild-type and mutant human thymidylate kinase suggest reasons for the mutants’ improved kinetics with the HIV prodrug metabolite AZTMP 1 1Edited by J. Karn
2000 · Nils Ostermann, Arnon Lavie, et al. · Journal of Molecular Biology · 52
Actomyosin Regulatory Properties of Yeast Tropomyosin Are Dependent upon N-Terminal Modification
2000 · R. Maytum, M. A. Geeves, et al. · Biochemistry · 52
Human 60-kDa Lysophospholipase Contains an N-terminal l-Asparaginase Domain That Is Allosterically Regulated by l-Asparagine
2014 · Christos S. Karamitros, Manfred Konrad · Journal of Biological Chemistry · 49
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Nonenantioselectivity Property of Human Deoxycytidine Kinase Explained by Structures of the Enzyme in Complex with l - and d -Nucleosides
2007 · Elisabetta Sabini, Saugata Hazra, et al. · Journal of Medicinal Chemistry · 49
Works count: 124
Citation count: 3,314
H-index: 36
I10-index: 70
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