Author

W. Frank An

Observed names: W An, W Frank An, W. An, W. Frank An

Observed institutions: Broad Institute, Boston Children's Hospital, Oregon State University, Harvard University, University of California, San Francisco, Massachusetts General Hospital, Horizon Discovery (United Kingdom), Beijing Biocytogen (China), Dana-Farber Cancer Institute, Stanley Center for Psychiatric Research, Massachusetts Institute of Technology

OpenAlex ID: A5113551845

Cell-Based Assays for High-Throughput Screening

2010 · W. Frank An, Nicola Tolliday · Molecular Biotechnology · 222

Identification of Regulators of Polyploidization Presents Therapeutic Targets for Treatment of AMKL

2012 · Qiang Wen, Benjamin Goldenson, et al. · Cell · 155

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Identification of Antifungal Compounds Active against Candida albicans Using an Improved High-Throughput Caenorhabditis elegans Assay

2009 · Ikechukwu Okoli, Jeffrey J. Coleman, et al. · PLoS ONE · 107

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Targeting BRCA1- and BRCA2-deficient cells with RAD52 small molecule inhibitors

2016 · Fei Huang, Nadish Goyal, et al. · Nucleic Acids Research · 102

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Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects

2016 · Florence F. Wagner, Joshua A. Bishop, et al. · ACS Chemical Biology · 74

Discovery of Selective Inhibitors of Endoplasmic Reticulum Aminopeptidase 1

2019 · Zachary Maben, Richa Arya, et al. · Journal of Medicinal Chemistry · 54

Introduction: Cell-Based Assays for High-Throughput Screening

2009 · W. Frank An, Nicola J. Tolliday · Methods in molecular biology · 44

AR Inhibitors Identified by High-Throughput Microscopy Detection of Conformational Change and Subcellular Localization

2009 · Jeremy O. Jones, W. Frank An, et al. · ACS Chemical Biology · 39

Linker histone protection of chromatosomes reconstituted on 5S rDNA from Xenopus borealis:a reinvestigation

1998 · W An · Nucleic Acids Research · 28

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Discovery of Potent and Highly Selective Inhibitors of GSK3b

2014 · W. Frank An, Andrew Germain, et al. · 27

Impact of Novel Screening Technologies on Ion Channel Drug Discovery

2008 · Qiang Lu, W. An · Combinatorial Chemistry & High Throughput Screening · 24

Fluorescence-Based Assays

2009 · W. Frank An · Methods in molecular biology · 18

Correction: Identification of Antifungal Compounds Active against Candida albicans Using an Improved High-Throughput Caenorhabditis elegans Assay

2010 · Ikechukwu Okoli, Jeffrey J. Coleman, et al. · PLoS ONE · 7

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Abstract 2619: A novel EGFR × HER3-targeting bispecific antibody drug-conjugate, BCG019, demonstrates robust anti-tumor efficacy in preclinical evaluation

2024 · Zhuolin Li, Chengzhang Shang, et al. · Cancer Research · 4

Abstract 6717: Targeting mutant KRAS proteins with novel TCR-mimic fully human antibodies

2024 · Jun Du, Wanbo Tang, et al. · Cancer Research · 2

Abstract 2617: BCG022, a novel HER3 × MET bispecific antibody-drug conjugate (bsADC), demonstrates promising anti-tumor efficacy

2024 · Zhuolin Li, Chengzhang Shang, et al. · Cancer Research · 2

Abstract 2621: Preclinical Efficacy of DM002, a bispecific HER3 × MUC1 antibody-drug conjugate with a novel DNA topoisomerase I inhibitor, in solid tumor models

2024 · Yifu Zhang, Chengzhang Shang, et al. · Cancer Research · 2

Phenothiazines Induce Apoptosis in T-Cell Acute Lymphoblastic Leukemia by Activating the Phosphatase Activity of the PP2A Tumor Suppressor

2012 · Alejandro Gutierrez, Alex Kentsis, et al. · Blood · 2

Abstract 2618: BCG017, a bispecific ADC targeting PTK7 and EGFR exhibits anti-tumor efficacy in PDX models

2024 · Sufei Yao, Chengzhang Shang, et al. · Cancer Research · 1

1150 DM005, an EGFR × MET bispecific antibody-drug conjugate, showed robust anti-tumor activity in PDX models

2023 · Yanfei Han, Wenjuan Dai, et al. · Regular and Young Investigator Award Abstracts · 1

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1164 BSA01, a bispecific antibody-drug conjugate targeting EGFR and membrane-bound MUC-1-C, exhibits anti-tumor efficacy in vivo

2023 · Yifu Zhang, Chengzhang Shang, et al. · Regular and Young Investigator Award Abstracts · 1

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1163 A novel bispecific antibody-drug conjugate targeting PTK7 and TROP2, BCG033, demonstrates preclinical efficacy against triple-negative breast cancer xenografts

2023 · Sufei Yao, Chengzhang Shang, et al. · Regular and Young Investigator Award Abstracts · 1

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Abstract 2724: BCG020, a novel bispecific antibody targeting EGFR and CD70, is effective against EGFR and CD70 high expressed tumors

2024 · Yongfei Yang, Xiaoxia Sun, et al. · Cancer Research

Abstract 2620: BCG016, a first-in-class bispecific antibody-drug conjugate targeting 5T4 and MUC1, demonstrates potent preclinical anti-tumor activity

2024 · Zhenyan Han, Chengzhang Shang, et al. · Cancer Research

1175 YH006, a fully human Treg-depleting CTLA-4×OX40 bispecific antibody, demonstrates superior preclinical efficacy and favorable developability

2023 · Baihong Liu, Xiang Guo, et al. · Regular and Young Investigator Award Abstracts

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Works count: 39

Citation count: 917

H-index: 12

I10-index: 12