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Atsuro Nakazato

MGS0039: a potent and selective group II metabotropic glutamate receptor antagonist with antidepressant-like activity
2003 · Shigeyuki Chaki, Ryoko Yoshikawa, et al. · Neuropharmacology · 262
Design, synthesis and structure–affinity relationships of aryloxyanilide derivatives as novel peripheral benzodiazepine receptor ligands
2003 · Taketoshi Okubo, Ryoko Yoshikawa, et al. · Bioorganic & Medicinal Chemistry · 160
Receptor Binding, Behavioral, and Electrophysiological Profiles of Nonpeptide Corticotropin-Releasing Factor Subtype 1 Receptor Antagonists CRA1000 and CRA1001
1999 · Shigeru Okuyama, Shigeyuki Chaki, et al. · Journal of Pharmacology and Experimental Therapeutics · 154
Anxiolytic- and antidepressant-like profile of a new CRF1 receptor antagonist, R278995/CRA0450
2003 · Shigeyuki Chaki, Atsuro Nakazato, et al. · European Journal of Pharmacology · 126
NE-100, a novel sigma receptor ligand: In vivo tests
1993 · Shigeru Okuyama, Yasuko Imagawa, et al. · Life Sciences · 119
Anxiolytic-Like and Antidepressant-Like Activities of MCL0129 (1-[(S)-2-(4-Fluorophenyl)-2-(4-isopropylpiperadin-1-yl)ethyl]-4-[4-(2-methoxynaphthalen-1-yl)butyl]piperazine), a Novel and Potent Nonpeptide Antagonist of the Melanocortin-4 Receptor
2003 · Shigeyuki Chaki, Shiho Hirota, et al. · Journal of Pharmacology and Experimental Therapeutics · 117
Synthesis, SARs, and Pharmacological Characterization of 2-Amino-3 or 6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid Derivatives as Potent, Selective, and Orally Active Group II Metabotropic Glutamate Receptor Agonists
2000 · Atsuro Nakazato, Toshihito Kumagai, et al. · Journal of Medicinal Chemistry · 116
Metabotropic glutamate 2/3 receptor antagonists improve behavioral and prefrontal dopaminergic alterations in the chronic corticosterone-induced depression model in mice
2012 · Yukio Ago, Koji Yano, et al. · Neuropharmacology · 93
Neuropharmacological profile of peripheral benzodiazepine receptor agonists, DAA1097 and DAA1106
1999 · Shigeru Okuyama, Shigeyuki Chaki, et al. · Life Sciences · 92
Binding characteristics of DAA1106, a novel and selective ligand for peripheral benzodiazepine receptors
1999 · Shigeyuki Chaki, Takeo Funakoshi, et al. · European Journal of Pharmacology · 85
Neuropharmacological profiles of antagonists of group II metabotropic glutamate receptors
2005 · Naoya Kawashima, Jun-ichi Karasawa, et al. · Neuroscience Letters · 66
Amino acid residues in the transmembrane domain of the type 1 sigma receptor critical for ligand binding
1999 · Hideko Yamamoto, Reiko Miura, et al. · FEBS Letters · 65
Synthesis, in Vitro Pharmacology, Structure−Activity Relationships, and Pharmacokinetics of 3-Alkoxy-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid Derivatives as Potent and Selective Group II Metabotropic Glutamate Receptor Antagonists
2004 · Atsuro Nakazato, Kazunari Sakagami, et al. · Journal of Medicinal Chemistry · 60
Design, synthesis, and structure?activity relationships of novel tetracyclic compounds as peripheral benzodiazepine receptor ligands*1
2004 · Taketoshi Okubo, Ryoko Yoshikawa, et al. · Bioorganic & Medicinal Chemistry · 59
Increased binding of cortical and hippocampal group II metabotropic glutamate receptors in isolation-reared mice
2010 · Toshiyuki Kawasaki, Yukio Ago, et al. · Neuropharmacology · 45
Effect of NE-100, a novel sigma receptor ligand, on phencyclidine-induced delayed cognitive dysfunction in rats
1995 · Shigeru Okuyama, Shin-ichi Ogawa, et al. · Neuroscience Letters · 45
MCL0042: A nonpeptidic MC4 receptor antagonist and serotonin reuptake inhibitor with anxiolytic- and antidepressant-like activity
2005 · Shigeyuki Chaki, Yuichi Oshida, et al. · Pharmacology Biochemistry and Behavior · 44
Prodrugs of 3-(3,4-dichlorobenzyloxy)-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (MGS0039): A potent and orally active group II mGluR antagonist with antidepressant-like potential
2006 · Akito Yasuhara, Masato Nakamura, et al. · Bioorganic & Medicinal Chemistry · 43
The atypical antipsychotic profile of NRA0045, a novel dopamine D4 and 5‐hydroxytryptamine2A receptor antagonist, in rats
1997 · Shigeru Okuyama, Shigeyuki Chaki, et al. · British Journal of Pharmacology · 42
NE‐100: A Novel Sigma Receptor Antagonist
1996 · Shigeru Okuyama, Atsuro Nakazato · CNS Drug Reviews · 40
Design, Synthesis, Structure−Activity Relationships, and Biological Characterization of Novel Arylalkoxyphenylalkylamine σ Ligands as Potential Antipsychotic Drugs
1999 · Atsuro Nakazato, Kohmei Ohta, et al. · Journal of Medicinal Chemistry · 38
NE-100, a novel sigma receptor ligand: Effect on phencyclidine-induced behaviors in rats, dogs and monkeys
1994 · Shigeru Okuyama, Yasuko Imagawa, et al. · Life Sciences · 38
In vitro pharmacological profile of nonpeptide CRF1 receptor antagonists, CRA1000 and CRA1001
1999 · Shigeyuki Chaki, Shigeru Okuyama, et al. · European Journal of Pharmacology · 34
The selective metabotropic glutamate 2/3 receptor agonist MGS0028 reverses psychomotor abnormalities and recognition memory deficits in mice lacking the pituitary adenylate cyclase-activating polypeptide
2012 · Yukio Ago, Naoki Hiramatsu, et al. · Behavioural Pharmacology · 33
The Selective Metabotropic Glutamate 2/3 Receptor Agonist MGS0028 Reverses Isolation Rearing–Induced Abnormal Behaviors in Mice
2012 · Yukio Ago, Ryota Araki, et al. · Journal of Pharmacological Sciences · 30
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Works count: 75
Citation count: 2,455
H-index: 27
I10-index: 46
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