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Anne M. Fourie
Observed names:
ANNE M. FOURIE,
Anne Fourie,
Anne M Fourie,
Fourie, Anne,
Fourie, Anne M.
Institutions:
Johnson & Johnson (United States),
Janssen Research & Development (United States)
Observed institutions:
Johnson & Johnson (United States),
University of Cape Town,
Janssen (United States),
Janssen Research & Development (United States),
General Atomics (United States)
ORCID:
0009-0006-9356-7082
Observed ORCID:
0009-0006-9356-7082
OpenAlex ID:
A5113580515
ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro
2005
·
Heather Stanton
, Fraser M. Rogerson
, et al.
·
Nature
·
925
Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation
2014
·
Pejman Soroosh
, Jiejun Wu
, et al.
·
Proceedings of the National Academy of Sciences
·
254
Catalytic Activity of ADAM8, ADAM15, and MDC-L (ADAM28) on Synthetic Peptide Substrates and in Ectodomain Cleavage of CD23
2003
·
Anne M. Fourie
, Fawn Coles
, et al.
·
Journal of Biological Chemistry
·
185
Impaired Immunoproteasome Assembly and Immune Responses in PA28 −/− Mice
1999
·
Tobias Preckel
, Wai-Ping Fung-Leung
, et al.
·
Science
·
177
IL-23 past, present, and future: a roadmap to advancing IL-23 science and therapy
2024
·
James G. Krueger
, Kilian Eyerich
, et al.
·
Frontiers in Immunology
·
160
PDF
Single-cell RNA sequencing of psoriatic skin identifies pathogenic Tc17 cell subsets and reveals distinctions between CD8+ T cells in autoimmunity and cancer
2020
·
Jared Liu
, Hsin-Wen Chang
, et al.
·
Journal of Allergy and Clinical Immunology
·
147
RORγt and RORα signature genes in human Th17 cells
2017
·
Glenda Castro
, Xuejun Liu
, et al.
·
PLoS ONE
·
143
PDF
Leukotriene B4 Receptors BLT1 and BLT2: Expression and Function in Human and Murine Mast Cells
2006
·
Katherine A Lundeen
, Binggang Sun
, et al.
·
The Journal of Immunology
·
127
PDF
Expression and Regulation of the Metalloproteinase ADAM-8 during Human Neutrophil Pathophysiological Activation and Its Catalytic Activity on L-Selectin Shedding
2007
·
Maria Gómez-Gaviro
, Maria Domínguez-Luis
, et al.
·
The Journal of Immunology
·
122
Targeting the Th17 pathway in psoriasis
2012
·
M Merle Elloso
, Mireia Gomez-Angelats
, et al.
·
Journal of Leukocyte Biology
·
113
Anti-Inflammatory Activity of a Potent, Selective Leukotriene A4 Hydrolase Inhibitor in Comparison with the 5-Lipoxygenase Inhibitor Zileuton
2007
·
Navin L. Rao
, Paul J. Dunford
, et al.
·
Journal of Pharmacology and Experimental Therapeutics
·
93
HSP70 Binding Sites in the Tumor Suppressor Protein p53
1997
·
Anne M. Fourie
, Ted R. Hupp
, et al.
·
Journal of Biological Chemistry
·
84
Pharmacologic modulation of RORγt translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis
2016
·
Xiaohua Xue
, Pejman Soroosh
, et al.
·
Scientific Reports
·
82
PDF
Leukotriene A4 Hydrolase Inhibition Attenuates Allergic Airway Inflammation and Hyperresponsiveness
2010
·
Navin L. Rao
, Jason P. Riley
, et al.
·
American Journal of Respiratory and Critical Care Medicine
·
63
Identification of a Potent, Selective, and Orally Active Leukotriene A4 Hydrolase Inhibitor with Anti-Inflammatory Activity
2008
·
Cheryl A. Grice
, Kevin L. Tays
, et al.
·
Journal of Medicinal Chemistry
·
61
JNJ-77242113, a highly potent, selective peptide targeting the IL-23 receptor, provides robust IL-23 pathway inhibition upon oral dosing in rats and humans
2024
·
Anne M. Fourie
, Xiaoli Cheng
, et al.
·
Scientific Reports
·
59
Preclinical and clinical characterization of the RORγt inhibitor JNJ-61803534
2021
·
Xiaohua Xue
, Aimee De Leon-Tabaldo
, et al.
·
Scientific Reports
·
45
PDF
Guselkumab binding to CD64+ IL-23–producing myeloid cells enhances potency for neutralizing IL-23 signaling
2025
·
Kacey L. Sachen
, Deepa Hammaker
, et al.
·
Frontiers in Immunology
·
44
Anti-Inflammatory Activity in Vitro and in Vivo of the Protein Farnesyltransferase Inhibitor Tipifarnib
2006
·
Xiaohua Xue
, Kuei-Tai A. Lai
, et al.
·
Journal of Pharmacology and Experimental Therapeutics
·
39
Identification and structure activity relationships of quinoline tertiary alcohol modulators of RORγt
2017
·
David A. Kummer
, Maxwell D. Cummings
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
27
Modulation of inflammatory disease by inhibitors of leukotriene A4 hydrolase.
2009
·
Anne M Fourie
·
PubMed
·
27
A novel B-RAF inhibitor blocks interleukin-8 (IL-8) synthesis in human melanoma xenografts, revealing IL-8 as a potential pharmacodynamic biomarker
2008
·
Shelby Crawford
, Daniel Belajic
, et al.
·
Molecular Cancer Therapeutics
·
27
Identification and biological evaluation of thiazole-based inverse agonists of RORγt
2018
·
Christian Gege
, Maxwell D. Cummings
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
25
6-Substituted quinolines as RORγt inverse agonists
2017
·
J. Kent Barbay
, Maxwell D. Cummings
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
25
Quantitation of leukotriene B4 in human sputum as a biomarker using UPLC–MS/MS
2013
·
Wenying Jian
, Richard W. Edom
, et al.
·
Journal of Chromatography B
·
24
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Works count:
57
Citation count:
3,259
H-index:
24
I10-index:
35
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