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Bryan G. Johnson

Observed names: B G Johnson, B. G. JOHNSON, B. G. Johnson, B.G JOHNSON, B.G Johnson, B.G. Johnson, Bryan G Johnson, Bryan Johnson, Johnson, B.G., Johnson, Bryan G.
OpenAlex ID: A5113583844
Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial
2007 · Sandeep T Patil, Lu Zhang, et al. · Nature Medicine · 1,037
Design, Synthesis, and Pharmacological Characterization of (+)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY354740): A Potent, Selective, and Orally Active Group 2 Metabotropic Glutamate Receptor Agonist Possessing Anticonvulsant and Anxiolytic Properties
1997 · James A. Monn, Matthew J. Valli, et al. · Journal of Medicinal Chemistry · 389
LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors
1998 · A.E Kingston, P.L Ornstein, et al. · Neuropharmacology · 368
Synthesis, Pharmacological Characterization, and Molecular Modeling of Heterobicyclic Amino Acids Related to (+)-2-Aminobicyclo[3.1.0]hexane- 2,6-dicarboxylic Acid (LY354740): Identification of Two New Potent, Selective, and Systemically Active Agonists for Group II Metabotropic Glutamate Receptors
1999 · James A. Monn, Matthew J. Valli, et al. · Journal of Medicinal Chemistry · 292
3,5‐Dihydroxyphenylglycine Is a Highly Selective Agonist for Phosphoinositide‐Linked Metabotropic Glutamate Receptors in the Rat Hippocampus
1994 · Darryle D. Schoepp, John Goldsworthy, et al. · Journal of Neurochemistry · 267
LY354740 is a Potent and Highly Selective Group II Metabotropic Glutamate Receptor Agonist in Cells Expressing Human Glutamate Receptors
1997 · D.D SCHOEPP, B.G JOHNSON, et al. · Neuropharmacology · 224
Evidence for the Role of Metabotropic Glutamate (mGlu)2 Not mGlu3 Receptors in the Preclinical Antipsychotic Pharmacology of the mGlu2/3 Receptor Agonist (–)-(1 R, 4 S,5 S,6 S)-4-Amino-2-sulfonylbicyclo[3.1.0]hexane-4,6-dicarboxylic Acid (LY404039)
2008 · Matthew J. Fell, Kjell A. Svensson, et al. · Journal of Pharmacology and Experimental Therapeutics · 204
Excitatory Amino Acid Agonist‐Antagonist Interactions at 2‐Amino‐4‐Phosphonobutyric Acid‐Sensitive Quisqualate Receptors Coupled to Phosphoinositide Hydrolysis in Slices of Rat Hippocampus
1988 · Darryle D. Schoepp, Bryan G. Johnson · Journal of Neurochemistry · 178
In vivo pharmacological characterization of the structurally novel, potent, selective mGlu2/3 receptor agonist LY404039 in animal models of psychiatric disorders
2007 · Linda M. Rorick-Kehn, Bryan G. Johnson, et al. · Psychopharmacology · 156
Inhibition of Cyclic AMP Formation by a Selective Metabotropic Glutamate Receptor Agonist
1992 · Darryle D. Schoepp, Bryan G. Johnson, et al. · Journal of Neurochemistry · 155
Discovery of a Potent, Peripherally Selective trans-3,4-Dimethyl-4-(3-hydroxyphenyl)piperidine Opioid Antagonist for the Treatment of Gastrointestinal Motility Disorders
1994 · Dennis M. Zimmerman, Jaswant S. Gidda, et al. · Journal of Medicinal Chemistry · 116
Group III human metabotropic glutamate receptors 4, 7 and 8: Molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells
1998 · Su Wu, Rebecca A Wright, et al. · Molecular Brain Research · 113
Inhibition of Excitatory Amino Acid‐Stimulated Phosphoinositide Hydrolysis in the Neonatal Rat Hippocampus by 2‐Amino‐3‐Phosphonopropionate
1989 · Darryle D. Schoepp, Bryan G. Johnson · Journal of Neurochemistry · 113
Increased anxiety-related behavior in mice deficient for metabotropic glutamate 8 (mGlu8) receptor
2002 · A.-M Linden, B.G Johnson, et al. · Neuropharmacology · 107
The Novel Metabotropic Glutamate Receptor Agonist 2 R ,4 R -APDC Potentiates Stimulation of Phosphoinositide Hydrolysis in the Rat Hippocampus by 3,5-dihydroxyphenylglycine: Evidence for a Synergistic Interaction Between Group 1 and Group 2 Receptors
1996 · D.D SCHOEPP, C.R SALHOFF, et al. · Neuropharmacology · 104
Stereoselectivity and mode of inhibition of phosphoinositide-coupled excitatory amino acid receptors by 2-amino-3-phosphonopropionic acid.
1990 · D D Schoepp, B G Johnson, et al. · Molecular Pharmacology · 101
[3H]-LY341495 as a novel antagonist radioligand for group II metabotropic glutamate (mGlu) receptors: characterization of binding to membranes of mGlu receptor subtype expressing cells
1999 · Bryan G Johnson, Rebecca A Wright, et al. · Neuropharmacology · 99
2-Substituted (2SR)-2-Amino-2-((1SR,2SR)-2-carboxycycloprop-1-yl)glycines as Potent and Selective Antagonists of Group II Metabotropic Glutamate Receptors. 2. Effects of Aromatic Substitution, Pharmacological Characterization, and Bioavailability
1998 · Paul L. Ornstein, Thomas J. Bleisch, et al. · Journal of Medicinal Chemistry · 99
CNS distribution of metabotropic glutamate 2 and 3 receptors: Transgenic mice and [3H]LY459477 autoradiography
2012 · Rebecca A. Wright, Bryan G. Johnson, et al. · Neuropharmacology · 96
Pharmacological and Pharmacokinetic Properties of a Structurally Novel, Potent, and Selective Metabotropic Glutamate 2/3 Receptor Agonist: In Vitro Characterization of Agonist (–)-(1 R,4 S,5 S,6 S)-4-Amino-2-sulfonylbicyclo[3.1.0]-hexane-4,6-dicarboxylic Acid (LY404039)
2007 · Linda M. Rorick-Kehn, Bryan G. Johnson, et al. · Journal of Pharmacology and Experimental Therapeutics · 93
Sigma opioid receptor: characterization and co-identity with the phencyclidine receptor.
1985 · L G Mendelsohn, V Kalra, et al. · Journal of Pharmacology and Experimental Therapeutics · 87
Comparison of (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD)- and 1R,3S-ACPD-stimulated brain phosphoinositide hydrolysis
1991 · Darryle D. Schoepp, Bryan G. Johnson, et al. · European Journal of Pharmacology Molecular Pharmacology · 84
Comparison of Excitatory Amino Acid‐Stimulated Phosphoinositide Hydrolysis and N‐[3H]Acetylaspartylglutamate Binding in Rat Brain: Selective Inhibition of Phosphoinositide Hydrolysis by 2‐Amino‐3‐Phosphonopropionate
1989 · Darryle D. Schoepp, Bryan G. Johnson · Journal of Neurochemistry · 79
Selective inhibition of excitatory amino acid-stimulated phosphoinositide hydrolysis in the rat hippocampus by activation of protein kinase C
1988 · Darryle D. Schoepp, Bryan G. Johnson · Biochemical Pharmacology · 78
Pharmacological Characterization of the Competitive GLUK5 Receptor Antagonist Decahydroisoquinoline LY466195 in Vitro and in Vivo
2006 · Brianne Weiss, Andrew Alt, et al. · Journal of Pharmacology and Experimental Therapeutics · 76
Works count: 80
Citation count: 6,250
H-index: 40
I10-index: 63
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