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Alan F. Cook

Observed names: A. F. COOK, A. F. Cook, A.F. Cook, ALAN COOK, ALAN F. COOK, Alan F Cook, Alan Frederick Cook, Alan Frederick. Cook
OpenAlex ID: A5113622232
Fluorinated pyrimidine nucleosides. 3. Synthesis and antitumor activity of a series of 5'-deoxy-5-fluoropyrimidine nucleosides
1979 · A. F. Cook, M. J. Holman, et al. · Journal of Medicinal Chemistry · 138
Structural and Functional Characterization of Potent Antithrombotic Oligonucleotides Possessing Both Quadruplex and Duplex Motifs
1995 · Roman F. Macaya, Janet A. Waldron, et al. · Biochemistry · 117
Synthesis and hybridization of a series of biotinylated oligonucleotides
1988 · Alan F. Cook, Edmund Vuocolo, et al. · Nucleic Acids Research · 93
Sulfoxide-carbodiimide reactions. VI. Synthesis of 2'-and 3'-ketouridines
1967 · Alan Frederick. Cook, John G. Moffatt · Journal of the American Chemical Society · 85
Isolation and synthesis of 1-methylisoguanosine, a potent pharmacologically active constituent from the marine sponge
1980 · Ronald J. Quiann, Richard P. Gregson, et al. · Tetrahedron Letters · 67
Carbodiimide-sulfoxide reactions. VII. Synthesis of stabilized sulfonium ylides
1968 · Alan Frederick Cook, John G. Moffatt · Journal of the American Chemical Society · 64
Displacement of [3H] diazepam binding in rat brain by dipyridamole and by 1-methylisoguanosine, a marine natural product with muscle relaxant activity
1980 · Les P. Davies, Alan F. Cook, et al. · Life Sciences · 62
Use of chloroacetic anhydride for the protection of nucleoside hydroxyl groups
1970 · Alan Frederick Cook, David T. Maichuk · The Journal of Organic Chemistry · 60
Nucleoside S-alkyl phosphorothioates. IV. Synthesis of nucleoside phosphorothioate monoesters
1970 · Alan F. Cook · Journal of the American Chemical Society · 60
1-Methylisoguanosine, a pharmacologically active agent from a marine sponge
1980 · Alan F. Cook, Robert T. Bartlett, et al. · The Journal of Organic Chemistry · 53
Annovel formamidine linker for use in solid-phase synthesis
1997 · Paul S. Furth, Michael S. Reitman, et al. · Tetrahedron Letters · 48
Oligonucleotides with novel, cationic backbone substituents: aminoethylphosphonates
1994 · Reza Fathi, Qing Huang, et al. · Nucleic Acids Research · 44
Use of 2,2,2-tribromoethyl chloroformate for the protection of nucleoside hydroxyl groups
1968 · Alan F. Cook · The Journal of Organic Chemistry · 40
Enzymatic cleavage of various fluorinated pyrimidine nucleosides to 5-fluorouracil and their antiproliferative activities in human and murine tumor cells.
1986 · MASANORI MIWA, ALAN COOK, et al. · Chemical and Pharmaceutical Bulletin · 36
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Nucleoside S-alkyl phosphorothioates. II. Preparation and chemical and enzymic properties
1969 · Alan F. Cook, Michael J. Holman, et al. · Journal of the American Chemical Society · 35
Synthesis and pharmacological evaluation of a series of analogs of 1-methylisoguanosine
1981 · Robert T. Bartlett, Alan F. Cook, et al. · Journal of Medicinal Chemistry · 32
Solid-Phase Synthesis of Novel Amino-Ether Derivatives
1997 · Paul S. Furth, Michael S. Reitman, et al. · Tetrahedron Letters · 28
(Aminomethyl)phosphonate derivatives of oligonucleotides
1994 · Reza Fathi, Qing Huang, et al. · Bioconjugate Chemistry · 28
Nucleoside S-alkyl phosphorothioates. III. Application to oligonucleotide synthesis
1969 · Alan F. Cook, Michael J. Holman, et al. · Journal of the American Chemical Society · 25
Synthesis and Properties of Combinatorial Libraries of Phosphoramidates
1996 · Reza Fathi, M. Jonathan Rudolph, et al. · The Journal of Organic Chemistry · 24
Stabilization of double-stranded oligonucleotides using backbone-linked disulfide bridges
1995 · Hetian Gao, Meihua Yang, et al. · Nucleic Acids Research · 24
Circularization of oligonucleotides by disulfide bridge formation
1995 · Hetian Gao, Meihua Yang, et al. · Nucleic Acids Research · 21
Nucleoside S-alkyl phosphorothioates. V. Synthesis of tridecadeoxyribonucleotide
1972 · Alan F. Cook, Edgar P. Heimer, et al. · Journal of the American Chemical Society · 21
Fluorinated pyrimidine nucleosides. 4. Synthesis and antitumor testing of a series of 2',5'-dideoxy- and 2',3',5'-trideoxynucleosides of 5-fluorouracil
1980 · A. F. Cook, M. J. Holman, et al. · Journal of Medicinal Chemistry · 14
Fluorinated pyrimidine nucleosides. 1. Synthesis of a nitrogen analog of the antitumor agent 2,2'-anhydro-1-.beta.-D-arabinofuranosyl-5-fluorocytosine hydrochloride
1977 · Alan F. Cook · Journal of Medicinal Chemistry · 13
Works count: 49
Citation count: 1,312
H-index: 21
I10-index: 30
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