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Jingkang Shen

Virtual Screening on Natural Products for Discovering Active Compounds and Target Information
2003 · Jianhua Shen, Xiaoying Xu, et al. · Current Medicinal Chemistry · 142
Pathological expression of tissue factor confers promising antitumor response to a novel therapeutic antibody SC1 in triple negative breast cancer and pancreatic adenocarcinoma
2017 · Xuesai Zhang, Qingrou Li, et al. · Oncotarget · 47
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Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody–Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function
2020 · Rui Jin, Liang Liu, et al. · Molecular Cancer Therapeutics · 35
Mechanism of the All-α to All-β Conformational Transition of RfaH-CTD: Molecular Dynamics Simulation and Markov State Model
2014 · Shanshan Li, Bing Xiong, et al. · Journal of Chemical Theory and Computation · 35
Efficient Synthesis of a (Z)-3-Methyleneisoindolin-1-one Library Using Cu(OAc)2•H2O/DBU under Microwave Irradiation
2013 · Li Zhang, Yongliang Zhang, et al. · Molecules · 32
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Preparation and reaction of 1H-pyrazolo[1,5-a]indoles as isoelectronic analogues of azulene (pseudoazulene)
1994 · Jing-Kang Shen, Hajime Katayama · Journal of the Chemical Society Perkin Transactions 1 · 28
AXL antibody and AXL-ADC mediate antitumor efficacy via targeting AXL in tumor-intrinsic epithelial-mesenchymal transition and tumor-associated M2-like macrophage
2023 · Jin-peng Pei, Yue Wang, et al. · Acta Pharmacologica Sinica · 25
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Tetrahydroisoquinolines as novel histone deacetylase inhibitors for treatment of cancer
2016 · Danqi Chen, Aijun Shen, et al. · Acta Pharmaceutica Sinica B · 25
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BSSF: a fingerprint based ultrafast binding site similarity search and function analysis server
2010 · Bing Xiong, Jie Wu, et al. · BMC Bioinformatics · 25
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The type IA topoisomerase catalytic cycle: A normal mode analysis and molecular dynamics simulation
2008 · Bing Xiong, David L. Burk, et al. · Proteins Structure Function and Bioinformatics · 19
Highly Stereoselective Nucleophilic Addition of Difluoromethyl‐2‐pyridyl Sulfone to Sugar Lactones and Efficient Synthesis of Fluorinated 2‐Ketoses
2014 · Xiao Liu, Qiang Yin, et al. · European Journal of Organic Chemistry · 18
Structure-Based Discovery of a Series of 5H-Pyrrolo[2,3-b]pyrazine FGFR Kinase Inhibitors
2018 · Alan Jiang, Qiufeng Liu, et al. · Molecules · 14
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Discovery of MTR-106 as a highly potent G-quadruplex stabilizer for treating BRCA-deficient cancers
2021 · Meng-Zhu Li, Tao Meng, et al. · Investigational New Drugs · 13
Tranylcypromine and 6-trifluoroethyl thienopyrimidine hybrid as LSD1 inhibitor
2019 · Xiaowen Wang, Mingbo Su, et al. · Bioorganic & Medicinal Chemistry Letters · 13
Nickel-Catalyzed Ligand-Free Systhesis of Benzoxazoles and Oxazolines via Isocyanide Insertion
2014 · Yong-Ming Zhu, Jing-Kang Shen, et al. · Heterocycles · 11
Intramolecular reaction of the hydrazonyl group with formyl and oxo groups: preparation of pyrazolo[1,5-a]indoles and related pyrazolo compounds
1993 · Jing-Kang Shen, Hajime Katayama, et al. · Journal of the Chemical Society Perkin Transactions 1 · 11
Synthesis and LAR inhibition of 7-alkoxy analogues of illudalic acid.
2010 · Qing Ling, Yue-Yang Zhou, et al. · PubMed · 10
Design and synthesis of benzylpiperidine inhibitors targeting the menin–MLL1 interface
2016 · Jing Ren, Wei Xu, et al. · Bioorganic & Medicinal Chemistry Letters · 9
Efficient syntheses of alpha - and beta-C -nucleosides and the origin of anomeric selectivity
2018 · Tongchao Liu, Zhengdan Zhu, et al. · Organic Chemistry Frontiers · 7
(N,N-Diisopropylcarbamoyloxy)-methyl p-tolyl sulfone: preparation and application for the syntheses of 1,2-diols
2012 · Lu Ma, Dongmei Zhao, et al. · Tetrahedron · 6
Preparation and Reactions of 3H-Pyrazolo(1,5-a)indole Derivatives.
1994 · Jing-Kang SHEN, Hajime KATAYAMA · Chemical and Pharmaceutical Bulletin · 6
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1H-pyrazolo(1,5-a)indoles: isoelectronic analogues of azulene (pseudoazulene).
1992 · Jing-Kang SHEN, Hajime KATAYAMA · Chemical and Pharmaceutical Bulletin · 6
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l-Chloroscoleurine mesylate
2006 · J. Li, G. Jin, et al. · Drugs of the Future · 5
Vilsmeier-Haack-Arnold and Bromination Reactions of 4H-Pyrazolo(1,5-a)indole Derivatives.
1994 · Jing-Kang SHEN, Hajime KATAYAMA, et al. · Chemical and Pharmaceutical Bulletin · 5
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Stereoselective N-glycosylation with N4-acyl cytosines and efficient synthesis of gemcitabine
2019 · Tongchao Liu, Jiadeng Tang, et al. · Tetrahedron · 4
Works count: 40
Citation count: 560
H-index: 13
I10-index: 17
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