Author

Bruce P. Damiano

Observed names: B P Damiano, B. P. Damiano, B.P. Damiano, Bruce Damiano, Bruce P Damiano, Bruce P. Damiano, Damiano, B.P., Damiano, Bruce

Institution: Janssen (Belgium)

Observed institutions: Scripps Research Institute, Pennsylvania State University, Johnson & Johnson (United States), Janssen (Belgium), Columbia University Irving Medical Center, Drug Discovery Laboratory (Norway), Janssen Research & Development (United States), Columbia University, Penn State Milton S. Hershey Medical Center

OpenAlex ID: A5113661064

A New Perspective in the Field of Cardiac Safety Testing through the Comprehensive In Vitro Proarrhythmia Assay Paradigm

2015 · Bernard Fermini, Jules C. Hancox, et al. · SLAS DISCOVERY · 303

Effects of pacing on triggered activity induced by early afterdepolarizations.

1984 · B P Damiano, M R Rosen · Circulation · 254

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Cardiovascular Responses Mediated by Protease-Activated Receptor-2 (PAR-2) and Thrombin Receptor (PAR-1) are Distinguished in Mice Deficient in PAR-2 or PAR-1

1999 · Bruce P. Damiano, Wai-Man Cheung, et al. · Journal of Pharmacology and Experimental Therapeutics · 182

Sustained electrical stimulation of the perforant path duplicates kainate-induced electrophysiological effects and hippocampal damage in rats

1981 · Robert S. Sloviter, Bruce P. Damiano · Neuroscience Letters · 176

Biological Consequences of Thrombin Receptor Deficiency in Mice

1996 · Andrew L Darrow, Wai-Ping Fung-Leung, et al. · Thrombosis and Haemostasis · 163

Blockade of the Thrombin Receptor Protease-Activated Receptor-1 with a Small-Molecule Antagonist Prevents Thrombus Formation and Vascular Occlusion in Nonhuman Primates

2003 · Claudia K. Derian, Bruce P. Damiano, et al. · Journal of Pharmacology and Experimental Therapeutics · 161

On the relationship between kainic acid-induced epileptiform activity and hippocampal neuronal damage

1981 · R.S. Sloviter, B.P. Damiano · Neuropharmacology · 151

Altered Vascular Injury Responses in Mice Deficient in Protease-Activated Receptor-1

1999 · Wai-man Cheung, Michael R. D’Andrea, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 119

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Administration of a Potent Antagonist of Protease-Activated Receptor-1 (PAR-1) Attenuates Vascular Restenosis Following Balloon Angioplasty in Rats

2001 · Patricia Andrade-Gordon, Claudia K. Derian, et al. · Journal of Pharmacology and Experimental Therapeutics · 112

General Principles for the Validation of Proarrhythmia Risk Prediction Models: An Extension of the CiPA In Silico Strategy

2019 · Zhihua Li, Gary R. Mirams, et al. · Clinical Pharmacology & Therapeutics · 109

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Novel bis(indolyl)maleimide pyridinophanes that are potent, selective inhibitors of glycogen synthase kinase-3

2007 · Han-Cheng Zhang, Llorente V.R. Boñaga, et al. · Bioorganic & Medicinal Chemistry Letters · 96

A Novel, Potent Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase

2005 · Lawrence de Garavilla, Michael N. Greco, et al. · Journal of Biological Chemistry · 91

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Mer Receptor Tyrosine Kinase Signaling Participates in Platelet Function

2004 · Cailin Chen, Quan Li, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 87

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Nonpeptide Urotensin-II Receptor Antagonists: A New Ligand Class Based on Piperazino-Phthalimide and Piperazino-Isoindolinone Subunits

2009 · Edward C. Lawson, Diane K. Luci, et al. · Journal of Medicinal Chemistry · 76

Discovery and Optimization of a Novel Series of Thrombin Receptor (PAR-1) Antagonists: Potent, Selective Peptide Mimetics Based on Indole and Indazole Templates

2001 · Han-Cheng Zhang, Claudia K. Derian, et al. · Journal of Medicinal Chemistry · 75

Potent, Orally Active GPIIb/IIIa Antagonists Containing a Nipecotic Acid Subunit. Structure−Activity Studies Leading to the Discovery of RWJ-53308

1999 · William J. Hoekstra, Bruce E. Maryanoff, et al. · Journal of Medicinal Chemistry · 71

Receptor-activating peptides distinguish thrombin receptor (PAR-1) and protease activated receptor 2 (PAR-2) mediated hemodynamic responses in vivo

1998 · Wai-man Cheung, Patricia Andrade-Gordon, et al. · Canadian Journal of Physiology and Pharmacology · 69

3-(7-Azaindolyl)-4-arylmaleimides as potent, selective inhibitors of glycogen synthase kinase-3

2004 · Han-Cheng Zhang, Hong Ye, et al. · Bioorganic & Medicinal Chemistry Letters · 66

Design and Optimization of Benzimidazole-Containing Transient Receptor Potential Melastatin 8 (TRPM8) Antagonists

2010 · Daniel J. Parks, William H. Parsons, et al. · Journal of Medicinal Chemistry · 65

Novel Indolylindazolylmaleimides as Inhibitors of Protein Kinase C-β: Synthesis, Biological Activity, and Cardiovascular Safety

2004 · Han-Cheng Zhang, Claudia K. Derian, et al. · Journal of Medicinal Chemistry · 61

Studies with an Orally Bioavailable αV Integrin Antagonist in Animal Models of Ocular Vasculopathy: Retinal Neovascularization in Mice and Retinal Vascular Permeability in Diabetic Rats

2007 · Rosemary J. Santulli, William A. Kinney, et al. · Journal of Pharmacology and Experimental Therapeutics · 59

Discovery of Potent, Selective, Orally Active, Nonpeptide Inhibitors of Human Mast Cell Chymase

2007 · Michael N. Greco, Michael J. Hawkins, et al. · Journal of Medicinal Chemistry · 59

7-Fluoroindazoles as Potent and Selective Inhibitors of Factor Xa

2007 · Yu-Kai Lee, Daniel J. Parks, et al. · Journal of Medicinal Chemistry · 55

A common mechanism for lysergic acid, indolealkylamine and phenethylamine hallucinogens: serotonergic medication of behavioral effects in rats.

1980 · R S Sloviter, E G Drust, et al. · Journal of Pharmacology and Experimental Therapeutics · 55

1,2,4-Triazolo[3,4-a]pyridine as a novel, constrained template for fibrinogen receptor (GPIIb/IIIa) antagonists

2001 · Edward C Lawson, William J Hoekstra, et al. · Bioorganic & Medicinal Chemistry Letters · 54

Works count: 94

Citation count: 3,659

H-index: 35

I10-index: 55