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Soumi Gupta

Pegvaliase for the treatment of phenylketonuria: Results of a long-term phase 3 clinical trial program (PRISM)
2018 · Janet Thomas, Harvey Levy, et al. · Molecular Genetics and Metabolism · 192
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Loss of Raltegravir Susceptibility by Human Immunodeficiency Virus Type 1 Is Conferred via Multiple Nonoverlapping Genetic Pathways
2009 · Signe Fransen, Soumi Gupta, et al. · Journal of Virology · 169
Association of immune response with efficacy and safety outcomes in adults with phenylketonuria administered pegvaliase in phase 3 clinical trials
2018 · Soumi Gupta, Kelly Lau, et al. · EBioMedicine · 75
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Evolution of Integrase Resistance During Failure of Integrase Inhibitor-Based Antiretroviral Therapy
2010 · Hiroyu Hatano, Harry Lampiris, et al. · JAIDS Journal of Acquired Immune Deficiency Syndromes · 72
Combinations of Mutations in the Connection Domain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Assessing the Impact on Nucleoside and Nonnucleoside Reverse Transcriptase Inhibitor Resistance
2010 · Soumi Gupta, Signe Fransen, et al. · Antimicrobial Agents and Chemotherapy · 49
The K101P and K103R/V179D Mutations in Human Immunodeficiency Virus Type 1 Reverse Transcriptase Confer Resistance to Nonnucleoside Reverse Transcriptase Inhibitors
2005 · Neil T. Parkin, Soumi Gupta, et al. · Antimicrobial Agents and Chemotherapy · 43
Substitutions at Amino Acid Positions 143, 148, and 155 of HIV-1 Integrase Define Distinct Genetic Barriers to Raltegravir Resistance In Vivo
2012 · Signe Fransen, Soumi Gupta, et al. · Journal of Virology · 42
Characterization of Human Immunodeficiency Virus Gag-Specific Gamma Interferon-Expressing Cells following Protective Mucosal Immunization with Alphavirus Replicon Particles
2005 · Soumi Gupta, Ramesh Janani, et al. · Journal of Virology · 40
Validation of an IFN-gamma ELISpot assay to measure cellular immune responses against viral antigens in non-human primates
2021 · Fan Yang, Kathryn Patton, et al. · Gene Therapy · 39
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2021 White Paper on Recent Issues in Bioanalysis: TAb/NAb, Viral Vector CDx, Shedding Assays; CRISPR/Cas9 & CAR-T Immunogenicity; PCR & Vaccine Assay Performance; ADA Assay Comparability & Cut Point Appropriateness ( Part 3 – Recommendations on Gene Therapy, Cell Therapy, Vaccine Assays; Immunogenicity of Biotherapeutics and Novel Modalities; Integrated Summary of Immunogenicity Harmonization)
2022 · Lina Loo, Shannon Harris, et al. · Bioanalysis · 37
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Comparison of Human Immunodeficiency Virus Type 1 Tropism Profiles in Clinical Samples by the Trofile and MT-2 Assays
2009 · Eoin Coakley, Jacqueline D. Reeves, et al. · Antimicrobial Agents and Chemotherapy · 35
Connection Domain Mutations in HIV-1 Reverse Transcriptase Do Not Impact Etravirine Susceptibility and Virologic Responses to Etravirine-Containing Regimens
2011 · Soumi Gupta, Johan Vingerhoets, et al. · Antimicrobial Agents and Chemotherapy · 33
Clinical immunogenicity outcomes from GENEr8-1, a phase 3 study of valoctocogene roxaparvovec, an AAV5-vectored gene therapy for hemophilia A
2024 · Brian R. Long, Tara M. Robinson, et al. · Molecular Therapy · 27
β7‐integrin‐independent enhancement of mucosal and systemic anti‐HIV antibody responses following combined mucosal and systemic gene delivery
2007 · Amanda Goodsell, Fengmin Zhou, et al. · Immunology · 22
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Vaccination of Cats with Attenuated Feline Immunodeficiency Virus Proviral DNA Vaccine Expressing Gamma Interferon
2006 · Soumi Gupta, Christian M. Leutenegger, et al. · Journal of Virology · 21
Maintenance of long-term immunological memory by low avidity IgM-secreting cells in bone marrow after mucosal immunizations with cholera toxin adjuvant
2003 · Elawati Soenawan, Indresh Srivastava, et al. · Vaccine · 21
Pharmacokinetic, pharmacodynamic, and immunogenic rationale for optimal dosing of pegvaliase, a PEGylated bacterial enzyme, in adult patients with phenylketonuria
2021 · Yulan Qi, Gina Patel, et al. · Clinical and Translational Science · 19
2022 White Paper on Recent Issues in Bioanalysis: Fda Draft Guidance on Immunogenicity Information in Prescription Drug Labeling, Lnp & Viral Vectors Therapeutics/Vaccines Immunogenicity, Prolongation Effect, Ada Affinity, Risk-Based Approaches, Ngs, Qpcr, Ddpcr Assays ( Part 3 – Recommendations on Gene Therapy, Cell Therapy, Vaccines Immunogenicity & Technologies; Immunogenicity & Risk Assessment of Biotherapeutics and Novel Modalities; NAb Assays Integrated Approach)
2023 · Luying Pan, Johanna Mora, et al. · Bioanalysis · 17
Antibody Responses against HIV in Rhesus Macaques following Combinations of Mucosal and Systemic Immunizations with Chimeric Alphavirus-Based Replicon Particles
2006 · Soumi Gupta, Fengmin Zhou, et al. · AIDS Research and Human Retroviruses · 14
Achieving efficacy in subjects with sustained pegvaliase-neutralizing antibody responses
2021 · Madhukar Aryal, Kelly Lau, et al. · Molecular Genetics and Metabolism · 11
Depletion of interfering IgG and IgM is critical to determine the role of IgE in pegvaliase-associated hypersensitivity
2019 · Kevin Larimore, Thom Nguyen, et al. · Journal of Immunological Methods · 11
Trends in Darunavir Resistance-Associated Mutations and Phenotypic Resistance in Commercially Tested United States Clinical Samples Between 2006 and 2012
2015 · Erkki Lathouwers, Soumi Gupta, et al. · AIDS Research and Human Retroviruses · 8
Virologic Characterization of HIV Type 1 With a Codon 70 Deletion in Reverse Transcriptase
2007 · Zixin Hu, Hiroyu Hatano, et al. · JAIDS Journal of Acquired Immune Deficiency Syndromes · 8
Construction and Characterization of Feline Immunodeficiency Virus Proviral Mutants That Coexpress Interferon Gamma and Green Fluorescent Protein
2006 · Soumi Gupta, Christian Leutenegger, et al. · AIDS Research and Human Retroviruses · 3
Interim 52-week analysis of immunogenicity to the vector capsid and transgene-expressed human FVIII in GENEr8-1, a phase 3 clinical study of valoctocogene roxaparvovec, an AAV5-mediated gene therapy for hemophilia A
2022 · Brian Long, Sylvia Fong, et al. · Journal of Hepatology · 2
Works count: 27
Citation count: 1,011
H-index: 17
I10-index: 21
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