Author

Jianghai Zhu

Institutions: National Institutes of Health, National Institute of Allergy and Infectious Diseases

Observed institutions: Boston Children's Hospital, National Institutes of Health, Howard Hughes Medical Institute, Harvard University, Medical College of Wisconsin, Purdue University West Lafayette, University of Michigan, Versiti Blood Center of Wisconsin, Department of Biological Sciences, National Institute of Allergy and Infectious Diseases

OpenAlex ID: A5113678045

Latent TGF-β structure and activation

2011 · Minlong Shi, Jianghai Zhu, et al. · Nature · 1,011

Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces

2008 · Jianghai Zhu, Bing-Hao Luo, et al. · Molecular Cell · 503

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Force interacts with macromolecular structure in activation of TGF-β

2017 · Xianchi Dong, Bo Zhao, et al. · Nature · 273

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Structural basis for distinctive recognition of fibrinogen γC peptide by the platelet integrin αIIbβ3

2008 · Timothy A. Springer, Jianghai Zhu, et al. · The Journal of Cell Biology · 236

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Complete integrin headpiece opening in eight steps

2013 · Jieqing Zhu, Jianghai Zhu, et al. · The Journal of Cell Biology · 213

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Structure of an integrin with an αI domain, complement receptor type 4

2009 · Can Xie, Jianghai Zhu, et al. · The EMBO Journal · 182

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GARP regulates the bioavailability and activation of TGFβ

2012 · Rui Wang, Jianghai Zhu, et al. · Molecular Biology of the Cell · 181

Closed headpiece of integrin αIIbβ3 and its complex with an αIIbβ3-specific antagonist that does not induce opening

2010 · Jieqing Zhu, Jianghai Zhu, et al. · Blood · 107

Structure-Guided Design of a High-Affinity Platelet Integrin α IIb β 3 Receptor Antagonist That Disrupts Mg 2+ Binding to the MIDAS

2012 · Jieqing Zhu, Won-Seok Choi, et al. · Science Translational Medicine · 97

Structural specializations of α4β7, an integrin that mediates rolling adhesion

2012 · Yamei Yu, Jianghai Zhu, et al. · The Journal of Cell Biology · 97

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αVβ3 Integrin Crystal Structures and Their Functional Implications

2012 · Xianchi Dong, Li-Zhi Mi, et al. · Biochemistry · 77

A New Arrangement of (β/α)8 Barrels in the Synthase Subunit of PLP Synthase

2005 · Jianghai Zhu, John W. Burgner, et al. · Journal of Biological Chemistry · 58

A general chemical principle for creating closure-stabilizing integrin inhibitors

2022 · Fu-Yang Lin, Jing Li, et al. · Cell · 57

Functional Dissection of the Bacillus subtilis pur Operator Site

2003 · Aloke Kumar Bera, Jianghai Zhu, et al. · Journal of Bacteriology · 42

β-Subunit Binding Is Sufficient for Ligands to Open the Integrin αIIbβ3 Headpiece

2015 · Fu-Yang Lin, Jianghai Zhu, et al. · Journal of Biological Chemistry · 32

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Structural basis for quinine-dependent antibody binding to platelet integrin αIIbβ3

2015 · Jianghai Zhu, Jieqing Zhu, et al. · Blood · 31

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Domain 1 of Mucosal Addressin Cell Adhesion Molecule Has an I1-set Fold and a Flexible Integrin-binding Loop

2013 · Yamei Yu, Jianghai Zhu, et al. · Journal of Biological Chemistry · 8

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Structural Basis for Quinine-Dependent Antibody Binding to Platelet Integrin alphaIIbbeta3

2015 · Jianghai Zhu, Jieqing Zhu, et al. · Blood · 3

Structural, Functional, and Dynamic Characterization of the Binding Site of RUC-1, a Novel αIIb-Specific Inhibitor of Integrin αIIbβ3.

2009 · Jieqing Zhu, Jianghai Zhu, et al. · Blood · 1

Structural bases for blockade and activation of BK channels by Ba2+ ions

2023 · Shubhra Srivastava, Pablo Miranda, et al. · Biophysical Journal

Structure-Guided Design of A Novel High Affinity Integrin αIIbβ3 Receptor Antagonist (RUC-2) That Displaces Mg2+ From the β3 MIDAS,

2011 · Jieqing Zhu, Won-Seok Choi, et al. · Blood

Computational Prediction and Experimental Validation of a Novel Binding Site for Platelet Integrin AlphaIIb-Beta3

2010 · Ana Negri, Davide Provasi, et al. · Biophysical Journal

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Structural study of a novel vitamin B6 biosynthetic pathway

2005 · Jianghai Zhu · Purdue e-Pubs (Purdue University System)

Works count: 24

Citation count: 3,264

H-index: 17

I10-index: 17