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Kazufumi Kubota
Observed name:
Kazufumi KUBOTA
Institution:
Daiichi-Sankyo (Japan)
Observed institutions:
University of Minnesota,
Daiichi-Sankyo (Japan)
OpenAlex ID:
A5113721097
Selective Blockade of the Capsaicin Receptor TRPV1 Attenuates Bone Cancer Pain
2005
·
Joseph R. Ghilardi
, Heidi Röhrich
, et al.
·
Journal of Neuroscience
·
391
PDF
Anti-NGF therapy profoundly reduces bone cancer pain and the accompanying increase in markers of peripheral and central sensitization
2005
·
Molly A. Sevcik
, Joseph R. Ghilardi
, et al.
·
Pain
·
324
A Blocking Antibody to Nerve Growth Factor Attenuates Skeletal Pain Induced by Prostate Tumor Cells Growing in Bone
2005
·
Kyle G. Halvorson
, Kazufumi Kubota
, et al.
·
Cancer Research
·
229
PDF
Tumor-induced injury of primary afferent sensory nerve fibers in bone cancer pain
2005
·
Christopher M. Peters
, Joseph R. Ghilardi
, et al.
·
Experimental Neurology
·
217
Pancreatic cancer pain and its correlation with changes in tumor vasculature, macrophage infiltration, neuronal innervation, body weight and disease progression
2005
·
Theodore H. Lindsay
, Beth M. Jonas
, et al.
·
Pain
·
125
Analgesic Efficacy of Bradykinin B1 Antagonists in a Murine Bone Cancer Pain Model
2005
·
Molly A. Sevcik
, Joseph R. Ghilardi
, et al.
·
Journal of Pain
·
59
Infantile Pain Episodes Associated with Novel Nav1.9 Mutations in Familial Episodic Pain Syndrome in Japanese Families
2016
·
Hiroko Okuda
, Atsuko Noguchi
, et al.
·
PLoS ONE
·
55
PDF
Simultaneous Inhibition of PGE2and PGI2Signals Is Necessary to Suppress Hyperalgesia in Rat Inflammatory Pain Models
2016
·
Ryusuke Sugita
, Harumi Kuwabara
, et al.
·
Mediators of Inflammation
·
36
PDF
Antinociceptive Effect and Enzymatic Degradation of Endomorphin-1 in Newborn Rat Spinal Cord
1999
·
Azusa Sugimoto-Watanabe
, Kazufumi Kubota
, et al.
·
The Japanese Journal of Pharmacology
·
29
Discovery of DS-1971a, a Potent, Selective NaV1.7 Inhibitor
2020
·
Tsuyoshi Shinozuka
, Hiroyuki Kobayashi
, et al.
·
Journal of Medicinal Chemistry
·
26
Voltage-gated calcium channel subunit α2δ-1 in spinal dorsal horn neurons contributes to aberrant excitatory synaptic transmission and mechanical hypersensitivity after peripheral nerve injury
2023
·
Keisuke Koga
, Kenta Kobayashi
, et al.
·
Frontiers in Molecular Neuroscience
·
21
PDF
A Novel Selective Prostaglandin E2 Synthesis Inhibitor Relieves Pyrexia and Chronic Inflammation in Rats
2016
·
Ryusuke Sugita
, Harumi Kuwabara
, et al.
·
Inflammation
·
19
Anxiolytic-like effects of mirogabalin, a novel ligand for α2δ ligand of voltage-gated calcium channels, in rats repeatedly injected with acidic saline intramuscularly, as an experimental model of fibromyalgia
2020
·
Hiroyasu Murasawa
, Hiroyuki Kobayashi
, et al.
·
Pharmacological Reports
·
17
Discovery of conolidine derivative DS39201083 as a potent novel analgesic without mu opioid agonist activity
2019
·
Tsuyoshi Arita
, Masayoshi Asano
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
14
Enhancing effect of dimethyl sulfoxide on nociceptive transmission in isolated spinal cord of newborn rat
1998
·
Kazufumi Kubota
, Kenji Fujibayashi
, et al.
·
European Journal of Pharmacology
·
12
N -Aryl Indoles as a Novel Class of Potent Na V 1.7 Inhibitors
2023
·
Narayan Karanjule
, Noriyuki Hayashi
, et al.
·
ACS Medicinal Chemistry Letters
·
8
PDF
Discovery of (phenoxy-2-hydroxypropyl)piperidines as a novel class of voltage-gated sodium channel 1.7 inhibitors
2015
·
Sayaka Suzuki
, Takeshi Kuroda
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
8
The Novel Gabapentinoid Mirogabalin Prevents Upregulation of α2δ-1 Subunit of Voltage-Gated Calcium Channels in Spinal Dorsal Horn in a Rat Model of Spinal Nerve Ligation
2022
·
Yuki Domon
, Naoko Kobayashi
, et al.
·
Drug Research
·
6
PDF
Discovery of DS34942424: An orally potent analgesic without mu opioid receptor agonist activity
2020
·
Tsuyoshi Arita
, Masayoshi Asano
, et al.
·
Bioorganic & Medicinal Chemistry
·
5
Effects of R-84760, a selective κ-opioid receptor agonist, on nociceptive reflex in isolated neonatal rat spinal cord
1998
·
Kenji Fujibayashi
, Kazufumi Kubota
, et al.
·
European Journal of Pharmacology
·
5
Discovery of a Novel Class of State-Dependent NaV1.7 Inhibitors for the Treatment of Neuropathic Pain
2020
·
Kyosuke Tanaka
, Hiroyuki Kobayashi
, et al.
·
Chemical and Pharmaceutical Bulletin
·
4
PDF
A novel method for detecting the analgesic effect of drugs by quantifying body movement after noxious stimulation in neonatal rat
1998
·
Kazufumi Kubota
, Tatsuhiko Takahashi
, et al.
·
Journal of Pharmacological and Toxicological Methods
·
4
A novel [5.2.1]bicyclic amine is a potent analgesic without µ opioid activity
2021
·
Tetsuji Noguchi
, Yuma Umezaki
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
3
Discovery of a novel bicyclic compound, DS54360155, as an orally potent analgesic without mu-opioid receptor agonist activity
2019
·
Tsuyoshi Arita
, Masayoshi Asano
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
3
A novel selective prostaglandin E2 synthesis inhibitor relieves pyrexia and arthritis in Guinea pigs inflammatory models
2016
·
Ryusuke Sugita
, Kazufumi Kubota
, et al.
·
Journal of Pharmacological Sciences
·
3
PDF
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Works count:
29
Citation count:
1,629
H-index:
14
I10-index:
15
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