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Walther J. A. A. van den Broek

Observed names: W J A A van den Broek, W J van den Broek, W.J.A.A. van den Broek, W.J.J.A. van den Broek, Walther J A A van den Broek, Walther J. A. A. Broeck, Walther J.A.A. van den Broek, Walther J.J.A. van den Broek, Walther JAA van den Broek, Walther van den Broek, Walther J. A. A. van den Broek, van den Broek, Walther, Jaa
OpenAlex ID: A5113724736
Abnormal myotonic dystrophy protein kinase levels produce only mild myopathy in mice
1996 · Gert Jansen, Patricia J.T.A. Groenen, et al. · Nature Genetics · 360
Triplet-repeat oligonucleotide-mediated reversal of RNA toxicity in myotonic dystrophy
2009 · Susan A. M. Mulders, Walther J. A. A. van den Broek, et al. · Proceedings of the National Academy of Sciences · 276
CRISPR/Cas9-Induced (CTG⋅CAG) n Repeat Instability in the Myotonic Dystrophy Type 1 Locus: Implications for Therapeutic Genome Editing
2017 · Ellen L. van Agtmaal, Laurène M. André, et al. · Molecular Therapy · 148
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Diet-induced hypercholesterolemia and atherosclerosis in heterozygous apolipoprotein E-deficient mice
1994 · Janine H. van Ree, Walther J.A.A. van den Broek, et al. · Atherosclerosis · 147
Phase I radioimmunotherapy of metastatic renal cell carcinoma with 131I-labeled chimeric monoclonal antibody G250.
1999 · M G Steffens, O C Boerman, et al. · PubMed · 113
Transgenic overexpression of human DMPK accumulates into hypertrophic cardiomyopathy, myotonic myopathy and hypotension traits of myotonic dystrophy
2004 · D. Fearghas O'Cochlain, Carmen Perez-Terzic, et al. · Human Molecular Genetics · 65
Increased response to cholesterol feeding in apolipoprotein C1-deficient mice
1995 · J H van Ree, M H Hofker, et al. · Biochemical Journal · 48
A low absolute number of expanded transcripts is involved in myotonic dystrophy type 1 manifestation in muscle
2016 · Anke E. E. G. Gudde, Anchel González-Barriga, et al. · Human Molecular Genetics · 46
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Fen1 does not control somatic hypermutability of the (CTG)n· (CAG)n repeat in a knock‐in mouse model for DM1
2006 · Walther J.A.A. van den Broek, Marcel R. Nelen, et al. · FEBS Letters · 40
Cell Membrane Integrity in Myotonic Dystrophy Type 1: Implications for Therapy
2015 · Anchel González-Barriga, Julia Kranzen, et al. · PLoS ONE · 29
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Somatic CTG•CAG repeat instability in a mouse model for myotonic dystrophy type 1 is associated with changes in cell nuclearity and DNA ploidy
2007 · Walther JAA van den Broek, Derick G Wansink, et al. · BMC Molecular Biology · 19
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Inactivation of Apoe and Apoc1 by two consecutive rounds of gene targeting: effects on mRNA expression levels of gene cluster members
1995 · Janine H. van Ree, Walther J.J.A. van den Broek, et al. · Human Molecular Genetics · 18
Deletion of the CTG Expansion in Myotonic Dystrophy Type 1 Reverses DMPK Aberrant Methylation in Human Embryonic Stem Cells but not Affected Myoblasts
2019 · Shira Yanovsky-Dagan, Ester Bnaya, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 11
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Differentiation shifts from a reversible to an irreversible heterochromatin state at the DM1 locus
2024 · Tayma Handal, Sarah Juster, et al. · Nature Communications · 10
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Diet-induced hypercholesterolemia and atherosclerosis in heterozygous apolipoprotein E-deficient mice
1994 · J.H. van Ree, W.J.A.A. van den Broek, et al. · Atherosclerosis · 7
Metastatic follicular carcinoma of the thyroid: reappearance of radioiodine uptake.
1995 · W J Oyen, A H Mudde, et al. · PubMed · 6
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Commitment to Myogenic Differentiation Significantly Aggravates the RNA Phenotype in Myotonic Dystrophy Type 1
2026 · Lise Ripken, Walther J. A. A. van den Broek, et al. · Neuropathology and Applied Neurobiology · 1
Diet induced hypercholesterolemia in apolipoprotein C1-deficient mice
1994 · Janine H. van Ree, Walther J. A. A. van den Broek, et al. · TNO Repository · 1
CRISPR/dCas9-mediated tuning of DMPK transcription reveals a quantitative relationship between toxic repeat RNA expression and MBNL1 activity in myotonic dystrophy
2026 · Lise Ripken, Thomas D Hoekman, et al. · Human Molecular Genetics
Generating Isogenic Myoblast Cell Models by CRISPR/Cas9-mediated Editing, Regulating and Targeting Genes in the Myotonic Dystrophy Type 1 (DM1) Locus
2017 · van Agtmaal, Ellen, L, Andre, Laurane, M, et al. · HAL
Mice deficient in both apolipoprotein E and C1 generated by consecutive gene targeting
1995 · J.H. van Ree, W.J.J.A. van den Broek, et al. · Atherosclerosis
Generation and Characterization of Apolipoprotein Cl-Deficient Mice
1995 · Marten H. Hofker, Janine H. Ree, et al. · Springer eBooks
Works count: 22
Citation count: 1,345
H-index: 12
I10-index: 14
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