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Brett H. Simmons
Observed names:
Brett H Simmons,
Brett Simmons,
Simmons Brett,
Simmons, Brett
Institution:
Pfizer (United States)
Observed institutions:
Pfizer (United States),
University Medical Center Hamburg-Eppendorf,
University of Rostock,
European Institute of Oncology,
University of California, Davis
OpenAlex ID:
A5113727478
HGF/c-Met Acts as an Alternative Angiogenic Pathway in Sunitinib-Resistant Tumors
2010
·
Farbod Shojaei
, Joseph H. Lee
, et al.
·
Cancer Research
·
333
Targeting Activin Receptor-Like Kinase 1 Inhibits Angiogenesis and Tumorigenesis through a Mechanism of Action Complementary to Anti-VEGF Therapies
2011
·
Dana D. Hu-Lowe
, Enhong Chen
, et al.
·
Cancer Research
·
132
PDF
Osteopontin induces growth of metastatic tumors in a preclinical model of non-small lung cancer
2012
·
Farbod Shojaei
, Nathan Scott
, et al.
·
Journal of Experimental & Clinical Cancer Research
·
70
PDF
Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia
2017
·
Manoj K. Kashyap
, Carlos I. Amaya-Chanaga
, et al.
·
Journal of Hematology & Oncology
·
66
PDF
HGF/c-Met pathway is one of the mediators of sunitinib-induced tumor cell type-dependent metastasis
2012
·
Farbod Shojaei
, Brett H. Simmons
, et al.
·
Cancer Letters
·
63
A novel CXCR4 antagonist IgG1 antibody (PF-06747143) for the treatment of hematologic malignancies
2017
·
Shu-Hui Liu
, Yin Gu
, et al.
·
Blood Advances
·
54
PDF
VEGF is an important mediator of tumor angiogenesis in malignant lesions in a genetically engineered mouse model of lung adenocarcinoma
2013
·
Bharat K Majeti
, Joseph H Lee
, et al.
·
BMC Cancer
·
30
PDF
Comparison of dynamic contrast‐enhanced MR , ultrasound and optical imaging modalities to evaluate the antiangiogenic effect of PF ‐03084014 and sunitinib
2014
·
Cathy C. Zhang
, Zhengming Yan
, et al.
·
Cancer Medicine
·
26
PDF
Combination of a MEK inhibitor at sub-MTD with a PI3K/mTOR inhibitor significantly suppresses growth of lung adenocarcinoma tumors in KrasG12D-LSL mice
2012
·
Brett H. Simmons
, Joseph H. Lee
, et al.
·
Cancer Chemotherapy and Pharmacology
·
24
Contrast agents for quantitative microCT of lung tumors in mice.
2013
·
Kush Lalwani
, Anand Giddabasappa
, et al.
·
PubMed
·
13
A Novel CXCR4 Antagonist IgG1 Antibody (PF-06747143) for the Treatment of Hematological Malignancies
2014
·
Flavia Pernasetti
, Shu-Hui Liu
, et al.
·
Blood
·
9
Pyridine-3-propanoic acids: Discovery of dual PPARα/γ agonists as antidiabetic agents
2006
·
Paul S. Humphries
, Simon Bailey
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
9
Abstract 2649: Fc-effector function activity of the CXCR4 IgG1 antibody PF-06747143: a novel clinical candidate for the treatment of hematologic malignancies
2017
·
Flavia Pernasetti
, Shu-Hui Liu
, et al.
·
Cancer Research
Additional file 6: Figure S6. of Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia
2017
·
Kashyap, Manoj
, Amaya-Chanaga, Carlos
, et al.
·
Figshare
Additional file 4: Figure S4. of Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia
2017
·
Kashyap, Manoj
, Amaya-Chanaga, Carlos
, et al.
·
Figshare
Additional file 2: Figure S2. of Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia
2017
·
Kashyap, Manoj
, Amaya-Chanaga, Carlos
, et al.
·
Figshare
Additional file 1: Figure S1. of Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia
2017
·
Kashyap, Manoj
, Amaya-Chanaga, Carlos
, et al.
·
Figshare
Additional file 5: Figure S5. of Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia
2017
·
Kashyap, Manoj
, Amaya-Chanaga, Carlos
, et al.
·
Figshare
Additional file 3: Figure S3. of Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia
2017
·
Kashyap, Manoj
, Amaya-Chanaga, Carlos
, et al.
·
Figshare
Abstract 322: Dual targeting of the PI3K/mTOR pathways by PF-04691502 or PF-05212384 exhibits therapeutic effects against the metastatic disease progression in the Ovcar 3 disseminated model.
2013
·
Zhengming Yan
, Douglas Fang
, et al.
·
Cancer Research
Abstract 1512: Sunitinib-induced metastasis is tumor dependent and is mediated by c-Met/HGF pathway
2012
·
Farbod Shojaei
, Brett H. Simmons
, et al.
·
Cancer Research
Abstract 4480: Combination of a PI3K/mTOR inhibitor and a MEK inhibitor at suboptimal dose significantly inhibits growth of lung adenocarcinoma tumors in KrasG12D-LSL mice
2011
·
Farbod Shojaei
, Brett H. Simmons
, et al.
·
Cancer Research
Abstract 1446: Effect of PF-03475952, a potent and neutralizing CD44 antibody, on cancer cell apoptosis in vitro and metastasis in two orthotopic models
2010
·
Yuli Wang
, Jean Wang
, et al.
·
Cancer Research
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Works count:
30
Citation count:
829
H-index:
10
I10-index:
10
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