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Yoshihiko Shimokawa

OPC-67683, a Nitro-Dihydro-Imidazooxazole Derivative with Promising Action against Tuberculosis In Vitro and In Mice
2006 · Makoto Matsumoto, Hiroyuki Hashizume, et al. · PLoS Medicine · 768
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Chemical analysis of a benzofuran derivative, 2-(2-ethylaminopropyl)benzofuran (2-EAPB), eight synthetic cannabinoids, five cathinone derivatives, and five other designer drugs newly detected in illegal products
2014 · Nahoko Uchiyama, Yoshihiko Shimokawa, et al. · Forensic Toxicology · 109
Pharmacokinetics and Metabolism of Delamanid, a Novel Anti-Tuberculosis Drug, in Animals and Humans: Importance of Albumin Metabolism In Vivo
2015 · Katsunori Sasahara, Yoshihiko Shimokawa, et al. · Drug Metabolism and Disposition · 97
Characterization of four new designer drugs, 5-chloro-NNEI, NNEI indazole analog, α-PHPP and α-POP, with 11 newly distributed designer drugs in illegal products
2014 · Nahoko Uchiyama, Satoru Matsuda, et al. · Forensic Science International · 75
High performance liquid chromatographic methods for the determination of aripiprazole with ultraviolet detection in rat plasma and brain: Application to the pharmacokinetic study
2005 · Yoshihiko Shimokawa, Hitoshi Akiyama, et al. · Journal of Chromatography B · 75
Two new synthetic cannabinoids, AM-2201 benzimidazole analog (FUBIMINA) and (4-methylpiperazin-1-yl)(1-pentyl-1H-indol-3-yl)methanone (MEPIRAPIM), and three phenethylamine derivatives, 25H-NBOMe 3,4,5-trimethoxybenzyl analog, 25B-NBOMe, and 2C-N-NBOMe, identified in illegal products
2013 · Nahoko Uchiyama, Yoshihiko Shimokawa, et al. · Forensic Toxicology · 59
Benzophenone synthase from Garcinia mangostana L. pericarps
2012 · Natsajee Nualkaew, Hiroyuki Morita, et al. · Phytochemistry · 50
A structure-based mechanism for benzalacetone synthase from Rheum palmatum
2009 · Hiroyuki Morita, Yoshihiko Shimokawa, et al. · Proceedings of the National Academy of Sciences · 50
A synthetic cannabinoid FDU-NNEI, two 2H-indazole isomers of synthetic cannabinoids AB-CHMINACA and NNEI indazole analog (MN-18), a phenethylamine derivative N–OH-EDMA, and a cathinone derivative dimethoxy-α-PHP, newly identified in illegal products
2015 · Nahoko Uchiyama, Yoshihiko Shimokawa, et al. · Forensic Toxicology · 48
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Metabolic Mechanism of Delamanid, a New Anti-Tuberculosis Drug, in Human Plasma
2015 · Yoshihiko Shimokawa, Katsunori Sasahara, et al. · Drug Metabolism and Disposition · 47
Erratum to: Two new synthetic cannabinoids, AM-2201 benzimidazole analog (FUBIMINA) and (4-methylpiperazin-1-yl)(1-pentyl-1H-indol-3-yl)methanone (MEPIRAPIM), and three phenethylamine derivatives, 25H-NBOMe 3,4,5-trimethoxybenzyl analog, 25B-NBOMe, and 2C-N-NBOMe, identified in illegal products
2013 · Nahoko Uchiyama, Yoshihiko Shimokawa, et al. · Forensic Toxicology · 46
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Delamanid Does Not Inhibit or Induce Cytochrome P450 Enzymes in Vitro
2014 · Yoshihiko Shimokawa, Katsunori Sasahara, et al. · Biological and Pharmaceutical Bulletin · 43
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Inhibition of Human Drug Metabolizing Cytochrome P450 by Buprenorphine.
2002 · Ken Umehara, Yoshihiko Shimokawa, et al. · Biological and Pharmaceutical Bulletin · 40
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Cloning and Structure-Function Analyses of Quinolone- and Acridone-producing Novel Type III Polyketide Synthases from Citrus microcarpa
2013 · Takahiro Mori, Yoshihiko Shimokawa, et al. · Journal of Biological Chemistry · 37
Structure Function Analysis of Novel Type III Polyketide Synthases from Arabidopsis thaliana
2008 · Yuusuke Mizuuchi, Yoshihiko Shimokawa, et al. · Biological and Pharmaceutical Bulletin · 36
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Absorption, distribution and excretion of the anti‐tuberculosis drug delamanid in rats: Extensive tissue distribution suggests potential therapeutic value for extrapulmonary tuberculosis
2017 · Masakazu Shibata, Yoshihiko Shimokawa, et al. · Biopharmaceutics & Drug Disposition · 25
Inhibitory Potential of Twenty Five Anti-tuberculosis Drugs on CYP Activities in Human Liver Microsomes
2015 · Yoshihiko Shimokawa, Noriaki Yoda, et al. · Biological and Pharmaceutical Bulletin · 25
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Antitubercular Agent Delamanid and Metabolites as Substrates and Inhibitors of ABC and Solute Carrier Transporters
2016 · Hiroyuki Sasabe, Yoshihiko Shimokawa, et al. · Antimicrobial Agents and Chemotherapy · 16
Liquid Chromatography-Tandem Mass Spectrometry Methods for Determination of Delamanid in Mouse Plasma and Lung
2015 · Yukihiro Hirao, Toshihisa Koga, et al. · American Journal of Analytical Chemistry · 14
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Benzalacetone Synthase
2012 · Yoshihiko Shimokawa, Hiroyuki Morita, et al. · Frontiers in Plant Science · 14
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Nutritional status of Aureobasidium sp. ATCC 20524 for the production of ?-fructofuranosidase
1991 · S. Hayashi, Y. Shimokawa, et al. · World Journal of Microbiology and Biotechnology · 11
Effect of Probucol on Cytochrome P450 Activities in Human Liver Microsomes.
2002 · Ken Umehara, Yoshihiko Shimokawa, et al. · Biological and Pharmaceutical Bulletin · 9
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Effect of .GAMMA.-Oryzanol on Cytochrome P450 Activities in Human Liver Microsomes
2004 · Ken Umehara, Yoshihiko Shimokawa, et al. · Biological and Pharmaceutical Bulletin · 7
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Effect of deglycosylation on the properties of β-fructofuranosidaseP-1 fromAureobasidium sp. ATCC 20524
1992 · Sachio Hayashi, Masaharu Nonoguchi, et al. · Journal of Industrial Microbiology & Biotechnology · 7
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Structure-based engineering of benzalacetone synthase
2010 · Yoshihiko Shimokawa, Hiroyuki Morita, et al. · Bioorganic & Medicinal Chemistry Letters · 6
Works count: 31
Citation count: 1,731
H-index: 17
I10-index: 21
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