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Cell Transformation by Retrovirus

Funding type: research
Funder scheme: R35
Start date: 1994-07-26
End date: 2001-04-30
Investigator: HIDESABURO HANAFUSA
Institution: ROCKEFELLER UNIVERSITY
Funded outputs count: 79
Funder award ID: 5r35ca044356-10
OpenAlex ID: G1027556248
A Role for RAS in V-CRK Transformation
2025 · Greulich, Heidi · PubMed · 21
A p130 Cas tyrosine phosphorylated substrate domain decoy disrupts v-Crk signaling
2002 · Kathrin H Kirsch, Margaret Kensinger, et al. · BMC Cell Biology · 24
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Crk family adaptor proteins trans‐activate c‐Abl kinase
2001 · Tomoyuki Shishido, Tsuyoshi Akagi, et al. · Genes to Cells · 55
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The Adapter Type Protein CMS/CD2AP Binds to the Proto-oncogenic Protein c-Cbl through a Tyrosine Phosphorylation-regulated Src Homology 3 Domain Interaction
2001 · Kathrin H. Kirsch, Maria-Magdalena Georgescu, et al. · Journal of Biological Chemistry · 85
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v-Crk activates the phosphoinositide 3-kinase/AKT pathway in transformation
2000 · Tsuyoshi Akagi, Tomoyuki Shishido, et al. · Proceedings of the National Academy of Sciences · 135
The kinase-deficient Src acts as a suppressor of the Abl kinase for Cbl phosphorylation
2000 · Tomoyuki Shishido, Tsuyoshi Akagi, et al. · Proceedings of the National Academy of Sciences · 25
TRANCE, a TNF Family Member, Activates Akt/PKB through a Signaling Complex Involving TRAF6 and c-Src
1999 · Brian R Wong, Daniel Besser, et al. · Molecular Cell · 593
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The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region
1999 · Maria-Magdalena Georgescu, Kathrin H. Kirsch, et al. · Proceedings of the National Academy of Sciences · 318
CMS: An adapter molecule involved in cytoskeletal rearrangements
1999 · Kathrin H. Kirsch, Maria-Magdalena Georgescu, et al. · Proceedings of the National Academy of Sciences · 163
A Single Amino Acid Substitution in the v-Eyk Intracellular Domain Results in Activation of Stat3 and Enhances Cellular Transformation
1999 · Daniel Besser, Jacqueline F. Bromberg, et al. · Molecular and Cellular Biology · 123
Biological Effects of c-Mer Receptor Tyrosine Kinase in Hematopoietic Cells Depend on the Grb2 Binding Site in the Receptor and Activation of NF-κB
1999 · Maria-Magdalena Georgescu, Kathrin H. Kirsch, et al. · Molecular and Cellular Biology · 100
Direct Binding of p130Cas to the Guanine Nucleotide Exchange Factor C3G
1998 · Kathrin H. Kirsch, Maria-Magdalena Georgescu, et al. · Journal of Biological Chemistry · 94
Activation of Rho-Dependent Cell Spreading and Focal Adhesion Biogenesis by the v-Crk Adaptor Protein
1998 · Zeynep F. Altun-Gultekin, Sanjay Chandriani, et al. · Molecular and Cellular Biology · 73
Development of highly selective SH3 binding peptides for Crk and CRKL which disrupt Crk-complexes with DOCK180, SoS and C3G
1998 · Guido Posern, Jie Zheng, et al. · Oncogene · 78
BRCA1 regulates p53-dependent gene expression
1998 · Toru Ouchi, Alvaro N. A. Monteiro, et al. · Proceedings of the National Academy of Sciences · 375
Guanine-Nucleotide Exchange Protein C3G Activates JNK1 by a Ras-independent Mechanism
1998 · Shinya Tanaka, Hidesaburo Hanafusa · Journal of Biological Chemistry · 71
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Src-induced activation of inducible T cell kinase (ITK) requires phosphatidylinositol 3-kinase activity and the Pleckstrin homology domain of inducible T cell kinase
1997 · Avery August, Ali Sadra, et al. · Proceedings of the National Academy of Sciences · 178
Common BRCA1 Variants and Transcriptional Activation
1997 · ALVARO N.A. MONTEIRO, AVERY AUGUST, et al. · The American Journal of Human Genetics · 37
Cell to substratum adhesion is involved in v-Src-induced cellular protein tyrosine phosphorylation: implication for the adhesion-regulated protein tyrosine phosphatase activity
1997 · Hisataka Sabe, Michinari Hamaguchi, et al. · Oncogene · 24
Downstream of Crk adaptor signaling pathway: Activation of Jun kinase by v-Crk through the guanine nucleotide exchange protein C3G
1997 · Shinya Tanaka, Toru Ouchi, et al. · Proceedings of the National Academy of Sciences · 135
v-Crk-induced cell transformation: changes in focal adhesion composition and signaling
1997 · Mirjam G. Nievers, Raymond B. Birge, et al. · Journal of Cell Science · 44
Evidence for a transcriptional activation function of BRCA1 C-terminal region
1996 · Alvaro N. A. Monteiro, Avery August, et al. · Proceedings of the National Academy of Sciences · 446
Identification of the Product of Growth Arrest-specific Gene 6 as a Common Ligand for Axl, Sky, and Mer Receptor Tyrosine Kinases
1996 · Kyoko Nagata, Kazumasa Ohashi, et al. · Journal of Biological Chemistry · 532
Proline-rich sequences mediate the interaction of the Arg protein tyrosine kinase with Crk.
1996 · B Wang, T Mysliwiec, et al. · PubMed · 26
Unique signal transduction of Eyk: constitutive stimulation of the JAK‐STAT pathway by an oncogenic receptor‐type tyrosine kinase.
1996 · C. Zong, R. Yan, et al. · The EMBO Journal · 77
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