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Immunological therapies for cancer, chronic infection and autoimmunity

Funding type: research
Funder scheme: Programs - Program Grant
Start date: 2015-01-01
Investigator: Ranjeny Thomas
Funded outputs count: 34
Funder award ID: 1071822
OpenAlex ID: G1181566010
Proinflammatory macrophages transporting gut-derived bacterial DNA drive autoimmune arthritis in spondyloarthropathy
2025 · Benjamin Cai, Rabina Giri, et al. · JCI Insight · 5
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Environmental pathways affecting gene expression (E.PAGE) as an R package to predict gene–environment associations
2022 · Sachin Muralidharan, Sarah Ali, et al. · Scientific Reports · 6
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Deficiencies of Runx3 and tissue-resident CD4 + intestinal epithelial lymphocytes link intestinal dysbiosis and inflammation in mouse and human spondyloarthropathy
2022 · Zaied Ahmed Bhuyan, Muralidhara Rao Maradana, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Skin Cancer-Associated S. aureus Strains Can Induce DNA Damage in Human Keratinocytes by Downregulating DNA Repair and Promoting Oxidative Stress
2022 · Annika Krueger, Ahmed Mohamed, et al. · Cancers · 35
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Etude des mécanismes pathogéniques impliquant l’immunité innée dans les spondyloarthrites
2022 · Xavier Romand
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Changes in the skin microbiome associated with squamous cell carcinoma in transplant recipients
2022 · Annika Krueger, Julian Zaugg, et al. · ISME Communications · 15
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Secreted Toxins From Staphylococcus aureus Strains Isolated From Keratinocyte Skin Cancers Mediate Pro-tumorigenic Inflammatory Responses in the Skin
2022 · Annika Krueger, Julian Zaugg, et al. · Frontiers in Microbiology · 32
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Upper Respiratory Tract Microbiome of Australian Aboriginal and Torres Strait Islander Children in Ear and Nose Health and Disease
2021 · Andrea Coleman, Julian Zaugg, et al. · Microbiology Spectrum · 22
Tolerance induction by liposomes targeting a single CD8 epitope IGRP206–214 in a model of type 1 diabetes is impeded by co‐targeting a CD4+ islet epitope
2021 · Irina Buckle, Jeniffer D Loaiza Naranjo, et al. · Immunology and Cell Biology · 9
Preclinical models of arthritis for studying immunotherapy and immune tolerance
2021 · Gavin R Meehan, Ranjeny Thomas, et al. · Annals of the Rheumatic Diseases · 42
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Mediation of Interleukin‐23 and Tumor Necrosis Factor–Driven Reactive Arthritis by Chlamydia‐Infected Macrophages in SKG Mice
2021 · Xavier Romand, Xiao Liu, et al. · Arthritis & Rheumatology · 20
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Streptococcus species enriched in the oral cavity of patients with RA are a source of peptidoglycan-polysaccharide polymers that can induce arthritis in mice
2021 · Rabia Moentadj, Yiwen Wang, et al. · Annals of the Rheumatic Diseases · 46
CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetes
2020 · Aditi Narsale, Breanna Lam, et al. · JCI Insight · 25
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Regulatory T Cells but Not IL-10 Impair Cell-Mediated Immunity in Human Papillomavirus E7+ Hyperplastic Epithelium
2020 · Abate Assefa Bashaw, Chenhao Zhou, et al. · Journal of Investigative Dermatology · 8
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Epistatic interactions between killer immunoglobulin-like receptors and human leukocyte antigen ligands are associated with ankylosing spondylitis
2020 · Aimee L. Hanson, Damjan Vukcevic, et al. · PLoS Genetics · 19
Altered Repertoire Diversity and Disease‐Associated Clonal Expansions Revealed by T Cell Receptor Immunosequencing in Ankylosing Spondylitis Patients
2020 · Aimee L. Hanson, Hendrik J. Nel, et al. · Arthritis & Rheumatology · 62
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Murine cytomegalovirus infection exacerbates complex IV deficiency in a model of mitochondrial disease
2020 · Nicola Ferreira, Christopher E. Andoniou, et al. · PLoS Genetics · 8
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Regulatory T Cells Induced by Single-Peptide Liposome Immunotherapy Suppress Islet-Specific T Cell Responses to Multiple Antigens and Protect from Autoimmune Diabetes
2020 · Anne-Sophie Bergot, Irina Buckle, et al. · The Journal of Immunology · 47
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Continuous pre- and post-transplant exposure to a disease-associated gut microbiome promotes hyper-acute graft-versus-host disease in wild-type mice
2020 · Kate L Bowerman, Antiopi Varelias, et al. · Gut Microbes · 27
Panel 4: Recent advances in understanding the natural history of the otitis media microbiome and its response to environmental pressures
2019 · Robyn L. Marsh, Celestine Aho, et al. · International Journal of Pediatric Otorhinolaryngology · 37
The microbiome and rheumatoid arthritis
2019 · Anne-Sophie Bergot, Rabina Giri, et al. · Best Practice & Research Clinical Rheumatology · 85
PD-L1– and calcitriol-dependent liposomal antigen-specific regulation of systemic inflammatory autoimmune disease
2019 · Ryan Galea, Hendrik J. Nel, et al. · JCI Insight · 66
Single-cell RNA sequencing reveals cell type-specific HPV expression in hyperplastic skin lesions
2019 · Katharina Devitt, Sarah J. Hanson, et al. · Virology · 23
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HPV16 E7-Driven Epithelial Hyperplasia Promotes Impaired Antigen Presentation and Regulatory T-Cell Development
2019 · Abate Assefa Bashaw, Siok M. Teoh, et al. · Journal of Investigative Dermatology · 17
Chemotherapy followed by anti-CD137 mAb immunotherapy improves disease control in a mouse myeloma model
2019 · Camille Guillerey, Kyohei Nakamura, et al. · JCI Insight · 31
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