Microfluidic Systems to Enable Enzyme Engineering for Chemical Synthesis
Description: PROJECT NARRATIVE Development of medicines requires technology for rapid and efficient synthesis of new molecules. This project will develop of a novel platform for high-throughput reaction development and discovery based on engineering enzymes using nanoliter droplet technology and high-throughput analytical systems compatible with organic reactions. By providing access to enhanced throughput and miniaturization, this technology will accelerate pharmaceutical discovery and development in a time and resource efficient manner.
Funder: National Institutes of Health
Amount: $473,200
Funding type: research
Funder scheme: R01
Start date: 2023-09-01
End date: 2027-05-31
Investigator: ROBERT T KENNEDY
Institution: UNIVERSITY OF MICHIGAN AT ANN ARBOR
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Funded outputs count: 1
Funder award ID: 1r01gm150948-01
OpenAlex ID: G1558479129