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Social impact of integration of advanced stem cell technology and existing medicine

Description: This study aimed to assess the development of advanced stem cell technologies that can produce human germ cells and neural cells, then considered whether their application is justifiable, while assessing ethical, legal, and social issues. Regarding stem cell technology to produce germ cells, it was concluded that its reproductive use for restoring fertility in cancer survivors may be justifiable, despite remaining ethical and regulatory issues. Concerning stem cell technology for generating neural cells, it was too early for in-depth consideration on the justification yet. During this research, the investigators recognized the emerging issues surrounding genome editing in medical research, which had been also integrated into stem cell research, and published bioethics articles and talked at the US National Academies of Sciences. In addition, the principle investigator joined a special committee of Science Council of Japan, and contributed to the publication of a recommendation.
Amount: ¥4,810,000
Funding type: research
Funder scheme: Grant-in-Aid for Scientific Research (C)
Start date: 2014-04-01
End date: 2018-03-31
Investigator: Tetsuya Ishii
Institution: Hokkaido University
Funded outputs count: 16
Funder award ID: 26460586
OpenAlex ID: G1644471237
2018 · Tetsuya Ishii, Yuri Hibino · Reproductive Biomedicine & Society Online · 42
2017 · Tetsuya Ishii, César Palacios-González · Gender and the Genome · 6
2017 · Tetsuya Ishii, Mitinori Saitou · Trends in Molecular Medicine · 26
2017 · Tetsuya Ishii · Current Opinion in Endocrinology Diabetes and Obesity · 28
2016 · Tetsuya Ishii · Current Stem Cell Reports · 3
2016 · Tetsuya Ishii, Renee A Reijo Pera · Nature Biotechnology · 13
2016 · Motoko Araki, Tetsuya Ishii · Trends in biotechnology · 26
2015 · Tetsuya Ishii · Briefings in Functional Genomics · 80
2015 · Tetsuya Ishii · Trends in Molecular Medicine · 80
2014 · Tetsuya Ishii · Journal of Clinical Medicine · 29
2014 · Tetsuya Ishii · World Journal of Stem Cells · 96
2014 · Motoko Araki, Tetsuya Ishii · Reproductive Biology and Endocrinology · 150
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