Neuroprotection by Modulating ER Stress in Glaucoma
Description: PROJECT NARRATIVE Glaucoma is the most common cause of irreversible blindness and will affect more than 100 million people between 40 to 80 years old by 2040. Based on our previous work that revealed the significant therapeutic potential of ER stress modulation for glaucomatous degeneration of optic nerve and retinal ganglion cells (RGCs), the proposed experiments will continue to develop novel neuroprotective strategies to preserve RGC and ON integrity and visual function.
Funder: National Eye Institute
Funding type: research
Funder scheme: R01
Start date: 2013-03-01
End date: 2024-02-29
Investigator: YANG HU
Institution: STANFORD UNIVERSITY
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Funded outputs count: 51
Funder award ID: R01EY023295
OpenAlex ID: G1755844792