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Training Program in Nutrition and Metabolism

Description: The relevance of the proposed grant relates to the large unmet need for training in translational nutrition research and the special populations served by this grant including pediatric and HIV-infected patients, for whom very little training specificall in nutrition research is available in the United States. The proposed grant involves a highly committed and well-accomplished faculty to accomplish this purpose and meet this need.
Funding type: training
Funder scheme: T32
Start date: 2005-09-27
End date: 2017-06-30
Investigator: STEVEN K. GRINSPOON
Institution: MASSACHUSETTS GENERAL HOSPITAL
Funded outputs count: 41
Funder award ID: T32HD052961
OpenAlex ID: G1817153103
Type 2 Diabetes and Obesity Alter Exercise Training-Induced Transcriptional Adaptations to Subcutaneous White Adipose Tissue
2025 · Roeland J.W. Middelbeek, Jiekun Yang, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Retinol binding protein 4 primes the NLRP3 inflammasome by signaling through Toll-like receptors 2 and 4
2020 · Pedro M. Moraes-Vieira, Mark M. Yore, et al. · Proceedings of the National Academy of Sciences · 94
Lorcaserin treatment decreases body weight and reduces cardiometabolic risk factors in obese adults: A six‐month, randomized, placebo‐controlled, double‐blind clinical trial
2019 · Dario Tuccinardi, Olivia M. Farr, et al. · Diabetes Obesity and Metabolism · 47
Effects of Pitavastatin on Insulin Sensitivity and Liver Fat: A Randomized Clinical Trial
2018 · Laurie R Braun, Meghan N Feldpausch, et al. · The Journal of Clinical Endocrinology & Metabolism · 32
Obese individuals with type 2 diabetes demonstrate decreased activation of the salience‐related insula and increased activation of the emotion/salience‐related amygdala to visual food cues compared to non‐obese individuals with diabetes: A preliminary study
2018 · Olivia M. Farr, Christos S. Mantzoros · Diabetes Obesity and Metabolism · 8
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Fibroblast growth factor 21 decreases after liver fat reduction via growth hormone augmentation
2017 · Laurie R. Braun, Meghan N. Feldpausch, et al. · Growth Hormone & IGF Research · 9
Impaired bone strength estimates at the distal tibia and its determinants in adolescents with anorexia nervosa
2017 · Vibha Singhal, Shreya Tulsiani, et al. · Bone · 63
Obese individuals with more components of the metabolic syndrome and/or prediabetes demonstrate decreased activation of reward-related brain centers in response to food cues in both the fed and fasting states: a preliminary fMRI study
2016 · O M Farr, C S Mantzoros · International Journal of Obesity · 20
Lorcaserin Administration Decreases Activation of Brain Centers in Response to Food Cues and These Emotion- and Salience-Related Changes Correlate With Weight Loss Effects: A 4-Week-Long Randomized, Placebo-Controlled, Double-Blind Clinical Trial
2016 · Olivia M. Farr, Jagriti Upadhyay, et al. · Diabetes · 50
Short-term administration of the GLP-1 analog liraglutide decreases circulating leptin and increases GIP levels and these changes are associated with alterations in CNS responses to food cues: A randomized, placebo-controlled, crossover study
2016 · Olivia M. Farr, Michael A. Tsoukas, et al. · Metabolism · 105
Differential Effects of Oral and Intravenous Lipid Administration on Key Molecules Related to Energy Homeostasis
2016 · Maria T. Vamvini, Ole-Petter Hamnvik, et al. · The Journal of Clinical Endocrinology & Metabolism · 19
Central nervous system regulation of eating: Insights from human brain imaging
2016 · Olivia M. Farr, Chiang-shan R. Li, et al. · Metabolism · 193
GLP-1 receptors exist in the parietal cortex, hypothalamus and medulla of human brains and the GLP-1 analogue liraglutide alters brain activity related to highly desirable food cues in individuals with diabetes: a crossover, randomised, placebo-controlled trial
2016 · Olivia M. Farr, Michail Sofopoulos, et al. · Diabetologia · 287
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Short- and long-term reproducibility of marrow adipose tissue quantification by 1H-MR spectroscopy
2015 · Vibha Singhal, Karen K. Miller, et al. · Skeletal Radiology · 24
Metabolic health and weight: Understanding metabolically unhealthy normal weight or metabolically healthy obese patients
2015 · Hannah Mathew, Olivia M. Farr, et al. · Metabolism · 182
Analysis of Multiple Families With Single Individuals Affected by Pseudohypoparathyroidism Type Ib (PHP1B) Reveals Only One Novel Maternally Inherited GNAS Deletion
2015 · Rieko Takatani, Angelo Molinaro, et al. · Journal of Bone and Mineral Research · 41
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Vertebral Strength and Estimated Fracture Risk Across the BMI Spectrum in Women
2015 · Katherine N Bachmann, Alexander G Bruno, et al. · Journal of Bone and Mineral Research · 41
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Early life adversity and/or posttraumatic stress disorder severity are associated with poor diet quality, including consumption of trans fatty acids, and fewer hours of resting or sleeping in a US middle-aged population: A cross-sectional and prospective study
2015 · Anna Gavrieli, Olivia M. Farr, et al. · Metabolism · 43
Leptin applications in 2015
2015 · Olivia M. Farr, Anna Gavrieli, et al. · Current Opinion in Endocrinology Diabetes and Obesity · 233
Regional fat depots and their relationship to bone density and microarchitecture in young oligo-amenorrheic athletes
2015 · Vibha Singhal, Giovana D.N. Maffazioli, et al. · Bone · 39
Posttraumatic stress disorder, alone or additively with early life adversity, is associated with obesity and cardiometabolic risk
2015 · O.M. Farr, B.-J. Ko, et al. · Nutrition Metabolism and Cardiovascular Diseases · 93
New research developments and insights from Metabolism
2014 · Olivia M. Farr, Michelle Camp, et al. · Metabolism · 2
The role of leptin in regulating bone metabolism
2014 · Jagriti Upadhyay, Olivia M. Farr, et al. · Metabolism · 267
Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects
2014 · Mark M. Yore, Ismail Syed, et al. · Cell · 842
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Stress- and PTSD-associated obesity and metabolic dysfunction: A growing problem requiring further research and novel treatments
2014 · Olivia M. Farr, Denise M. Sloan, et al. · Metabolism · 80
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