Profiling the Leishmania-macrophage Host-pathogen Infectome
Description: Narrative Protozoan parasites of the genus Leishmania afflict millions of people worldwide and pathologies range from mild cutaneous, self-healing lesions to fatal visceral disease. The proposed study aims to use new DNA sequencing technologies to identify genes in the mammalian-infective Leishmania stages on a genome-wide scale. Interactions between parasite and human proteins will be investigated, and results from this work will provide novel insights into Leishmania pathogenesis and guide efforts toward effective prevention or control of Leishmaniasis.
Funding type: research
Funder scheme: R01
Start date: 2011-09-01
End date: 2016-08-31
Investigator: NAJIB M EL-SAYED
Institution: UNIV OF MARYLAND, COLLEGE PARK
Field: Medicine
Domain: Health Sciences
Funded outputs count: 19
Funder award ID: R01AI094773
OpenAlex ID: G1874216632