Award

Development of a Machine Learning Model to Integrate Clinical, Laboratory, Sonographic, and Elastographic Data for Noninvasive Liver Tissue Characterization in NAFLD

Description: Project Narrative In this project, we aim to create low-cost non-invasive technology to diagnose people with high risk non-alcoholic steatohepatitis (hrNASH), a common liver disease that has a high risk of cirrhosis. We will accomplish this goal by improving liver ultrasound imaging and by creating a prediction tool that integrates liver ultrasound, laboratory testing and clinical information. This prediction tool has the potential to reduce the need for liver biopsies.
Funding type: research
Funder scheme: R01
Start date: 2019-01-20
End date: 2025-12-31
Investigator: ANTHONY EDWARD SAMIR
Institution: MASSACHUSETTS GENERAL HOSPITAL
Subfield: Epidemiology
Field: Medicine
Funded outputs count: 19
Funder award ID: R01DK119860
OpenAlex ID: G1891753662
2026 · Guangyi Zhang, Xiaohong Wang, et al. · Nature Communications
2024 · Siddhi Hegde, Theodore T. Pierce, et al. · Ultrasound in Medicine & Biology · 5
2024 · Firouzeh Heidari, Theodore T. Pierce, et al. · WFUMB Ultrasound Open · 4
2022 · David T. Fetzer, Ivan M. Rosado-Mendez, et al. · Radiology · 45
2022 · Shuhang Wang, Vivek Kumar Singh, et al. · Computers in Biology and Medicine · 36
2022 · Vivek Kumar Singh, Elham Yousef Kalafi, et al. · Expert Systems with Applications · 32
2022 · Arun J. Sanyal, Sudha S. Shankar, et al. · Nature Medicine · 56
2021 · Arinc Ozturk, Michael C. Olson, et al. · Abdominal Radiology · 174
2020 · Andrew T. Trout, Sudha A. Anupindi, et al. · Radiology · 58
2020 · Laura J. Brattain, Arinc Ozturk, et al. · Ultrasound in Medicine & Biology · 23
2020 · Hu, Szu-Yeu, Wang, Shuhang, et al. · arXiv (Cornell University) · 1
2020 · Masoud Baikpour, Arinc Ozturk, et al. · American Journal of Roentgenology · 34
2019 · Yingzhen N. Zhang, Kathryn J. Fowler, et al. · Journal of Magnetic Resonance Imaging · 118
2019 · Chen Cui, Shinn-Huey S. Chou, et al. · American Journal of Roentgenology · 9
2018 · Laura J. Brattain, Brian A. Telfer, et al. · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · 28
Year
Topic