Award

Gene Therapeutic Approaches to Cartilage Repair

Funder: National Institutes of Health

Amount: $122,400

Funding type: career_development

Funder scheme: K08

Start date: 2008-09-01

End date: 2013-12-30

Investigator: LAURIE GOODRICH

Institution: COLORADO STATE UNIVERSITY

Funded outputs count: 9

Funder award ID: 5k08ar054903-05

OpenAlex ID: G190462533

Addition of Mesenchymal Stem Cells to Autologous Platelet-Enhanced Fibrin Scaffolds in Chondral Defects

2016 · Laurie R. Goodrich, Albert C. Chen, et al. · Journal of Bone and Joint Surgery · 66

Adeno-associated virus gene therapy vector scAAVIGF-I for transduction of equine articular chondrocytes and RNA-seq analysis

2015 · D.D. Hemphill, C.W. McIlwraith, et al. · Osteoarthritis and Cartilage · 20

Comparison of subjective lameness evaluation, force platforms and an inertial-sensor system to identify mild lameness in an equine osteoarthritis model

2015 · J.R. Donnell, D.D. Frisbie, et al. · The Veterinary Journal · 59

scAAVIL-1ra dosing trial in a large animal model and validation of long-term expression with repeat administration for osteoarthritis therapy

2015 · L R Goodrich, J C Grieger, et al. · Gene Therapy · 47

Adeno-Associated Viral Vectors Show Serotype Specific Transduction of Equine Joint Tissue Explants and Cultured Monolayers

2014 · Daniel D. Hemphill, C. Wayne McIlwraith, et al. · Scientific Reports · 18

Optimization of scAAVIL-1ra In Vitro and In Vivo to Deliver High Levels of Therapeutic Protein for Treatment of Osteoarthritis

2013 · Laurie R Goodrich, Jennifer N Phillips, et al. · Molecular Therapy — Nucleic Acids · 57

Equine bone marrow‐derived mesenchymal stromal cells ( BMDMSC s) from the ilium and sternum: Are there differences?

2012 · M. K. Adams, L. R. Goodrich, et al. · Equine Veterinary Journal · 39

Use of a radiofrequency probe for tenoscopic‐guided annular ligament desmotomy

2011 · A. M. MCCOY, L. R. GOODRICH · Equine Veterinary Journal · 15

Osteoblastic differentiation of human and equine adult bone marrow‐derived mesenchymal stem cells when BMP‐2 or BMP‐7 homodimer genetic modification is compared to BMP‐2/7 heterodimer genetic modification in the presence and absence of dexamethasone

2010 · Ryan S. Carpenter, Laurie R. Goodrich, et al. · Journal of Orthopaedic Research® · 51