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内质网应激在药源性肝损伤中的作用和机制研究

Amount: ¥700,000
Funding type: grant
Funder scheme: 面上项目
Start date: 2012-01-01
End date: 2016-12-31
Investigator: 慧萍 周
Institution: 温州医科大学
Funded outputs count: 18
Funder award ID: 81270489
OpenAlex ID: G19147670
Conjugated Bile Acids Promote Invasive Growth of Esophageal Adenocarcinoma Cells and Cancer Stem Cell Expansion via Sphingosine 1-Phosphate Receptor 2–Mediated Yes-Associated Protein Activation
2018 · Runping Liu, Xiaojiaoyang Li, et al. · American Journal Of Pathology · 64
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The role of sphingosine kinase 2 in promoting multiple myeloma cell invasive growth
2018 · Hannah Zhang, Derrick Zhao, et al. · The FASEB Journal · 1
Cholangiocyte‐derived exosomal long noncoding RNA H19 promotes cholestatic liver injury in mouse and humans
2018 · Xiaojiaoyang Li, Runping Liu, et al. · Hepatology · 149
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Cordycepin inhibits LPS-induced inflammatory responses by modulating NOD-Like Receptor Protein 3 inflammasome activation
2017 · Jing Yang, Yun-zhou Li, et al. · Biomedicine & Pharmacotherapy · 38
C/EBP homologous protein–induced loss of intestinal epithelial stemness contributes to bile duct ligation–induced cholestatic liver injury in mice
2017 · Runping Liu, Xiaojiaoyang Li, et al. · Hepatology · 69
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Sphingosine Kinases/Sphingosine 1-Phosphate Signaling in Hepatic Lipid Metabolism
2017 · Eric K. Kwong, Xiaojiaoyang Li, et al. · Current Pharmacology Reports · 30
The role of long noncoding RNA H19 in gender disparity of cholestatic liver injury in multidrug resistance 2 gene knockout mice
2017 · Xiaojiaoyang Li, Runping Liu, et al. · Hepatology · 107
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The role of sphingosine 1‐phosphate receptor 2 in bile‐acid–induced cholangiocyte proliferation and cholestasis‐induced liver injury in mice
2017 · Yongqing Wang, Hiroaki Aoki, et al. · Hepatology · 239
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Role of AMP-activated protein kinase α1 in 17α-ethinylestradiol-induced cholestasis in rats
2016 · Xiaojiaoyang Li, Runping Liu, et al. · Archives of Toxicology · 44
Curcumin analog WZ35 induced cell death via ROS-dependent ER stress and G2/M cell cycle arrest in human prostate cancer cells
2015 · Xiuhua Zhang, Minxiao Chen, et al. · BMC Cancer · 86
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Selective killing of gastric cancer cells by a small molecule targeting ROS‐mediated ER stress activation
2015 · Peng Zou, Yiqun Xia, et al. · Molecular Carcinogenesis · 37
HIV Protease Inhibitors Sensitize Human Head and Neck Squamous Carcinoma Cells to Radiation by Activating Endoplasmic Reticulum Stress
2015 · Runping Liu, Luyong Zhang, et al. · PLoS ONE · 24
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Flavonoid Apigenin Inhibits Lipopolysaccharide-Induced Inflammatory Response through Multiple Mechanisms in Macrophages
2014 · Xiaoxuan Zhang, Guangji Wang, et al. · PLoS ONE · 265
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Reduction of the HIV Protease Inhibitor-Induced ER Stress and Inflammatory Response by Raltegravir in Macrophages
2014 · Xiaoxuan Zhang, Risheng Cao, et al. · PLoS ONE · 21
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Conjugated bile acids promote cholangiocarcinoma cell invasive growth through activation of sphingosine 1-phosphate receptor 2
2014 · Runping Liu, Renping Zhao, et al. · Hepatology · 186
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HIV Protease Inhibitors Disrupt Lipid Metabolism by Activating Endoplasmic Reticulum Stress and Inhibiting Autophagy Activity in Adipocytes
2013 · Beth S. Zha, Xiaoshan Wan, et al. · PLoS ONE · 79
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The role of CCAAT enhancer-binding protein homologous protein in human immunodeficiency virus protease-inhibitor–induced hepatic lipotoxicity in mice
2012 · Yun Wang, Luyong Zhang, et al. · Hepatology · 26
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Digital Culture and Academic Cyber-plagiarism
2011 · Y. Del Aguila Ríos · ICERI2011 Proceedings
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