Award

(PQB6) Genetics of Subclonal Evolution in Pancreatic Cancer

Description: PUBLIC HEALTH RELEVANCE: Pancreatic cancer is a devastating disease largely because it is diagnosed at a late stage when metastasis has already occurred. Our research has shown that once pancreatic cancers form they continue to accumulate mutations before they become metastatic. The goal of this proposal is to evaluate the relationship of these mutations to the acquisition of metastatic ability.
Funding type: research
Funder scheme: R01
Start date: 2013-09-01
End date: 2017-06-30
Investigator: CHRISTINE A IACOBUZIO-DONAHUE
Institution: SLOAN-KETTERING INST CAN RESEARCH
Funded outputs count: 30
Funder award ID: R01CA179991
OpenAlex ID: G1919989988
2021 · Alvin P. Makohon-Moore, Evan J. Lipson, et al. · Clinical Cancer Research · 15
2020 · Akimasa Hayashi, Aslihan Yavas, et al. · Modern Pathology · 66
2020 · Hitomi Sakamoto, Marc A. Attiyeh, et al. · Cancer Discovery · 118
2019 · Kamel Lahouel, Laurent Younes, et al. · Proceedings of the National Academy of Sciences · 55
2019 · Noushin Niknafs, Yi Zhong, et al. · Nature Communications · 24
2019 · Cristian Tomasetti, Justin Poling, et al. · Proceedings of the National Academy of Sciences · 96
2019 · Christine A. Iacobuzio-Donahue, Chelsea Michael, et al. · Nature reviews. Cancer · 89
2019 · Johannes G. Reiter, Marina Baretti, et al. · Nature reviews. Cancer · 208
2019 · Akimasa Hayashi, Jun Fan, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 4
2018 · Johannes G. Reiter, Alvin P. Makohon-Moore, et al. · Science · 301
2017 · Zachary A. Kohutek, Lauren M. Rosati, et al. · Molecular Case Studies · 7
2017 · Maria L. Ascierto, Alvin Makohon-Moore, et al. · Clinical Cancer Research · 83
2017 · Johannes G. Reiter, Alvin P. Makohon-Moore, et al. · Nature Communications · 166
2016 · Nicole M. Aiello, David L. Bajor, et al. · Nature Communications · 136
2016 · Alvin Makohon-Moore, Christine A. Iacobuzio-Donahue · Nature reviews. Cancer · 423
2016 · Katherine E. Poruk, Vicente Valero, et al. · Annals of Surgery · 155
2015 · Nemanja Rodić, Jared P Steranka, et al. · Nature Medicine · 144
Year
Topic