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1052949

Funded outputs count: 7
Funder award ID: 1052949
OpenAlex ID: G1924201848
Mechanism of activation of an ancestral TEC kinase by PIP3
2026 · Eva Krötenheerdt, Lucas Piëch, et al. · npj Structural Biology · 1
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Unconventional binding of calmodulin to CHK2 kinase inhibits catalytic activity
2025 · Christopher R. Horne, Tingting Wang, et al. · Biochemical Journal · 4
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Influenza A virus NS1 protein mimics oncogenic PI3K resulting in isoform specific cellular redistribution and activation
2025 · Sadaf Aslam, María T. Sánchez-Aparicio, et al. · Proceedings of the National Academy of Sciences · 2
Molecular insight on the role of the phosphoinositide PIP3 in regulating the protein kinases Akt, PDK1, and BTK
2025 · Alexandria L. Shaw, John E. Burke · Biochemical Society Transactions · 14
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ATP-competitive inhibitors of PI3K enzymes demonstrate an isoform selective dual action by controlling membrane binding
2024 · Grace Q. Gong, Glenn R. Masson, et al. · Biochemical Journal · 5
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Free energy landscape of the PI3Kα C-terminal activation
2024 · Danai Maria Kotzampasi, Michail Papadourakis, et al. · Computational and Structural Biotechnology Journal · 12
Rapid, potent, and persistent covalent chemical probes to deconvolute PI3Kα signaling
2024 · Lukas Bissegger, Theodora A. Constantin, et al. · Chemical Science · 8
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