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R01HL-087174

Funded outputs count: 40
Funder award ID: R01HL-087174
OpenAlex ID: G1936620225
Potential role of drug metabolizing enzymes in chemotherapy-induced gastrointestinal toxicity and hepatotoxicity
2020 · Gabriel Tao, Junqing Huang, et al. · Expert Opinion on Drug Metabolism & Toxicology · 52
Polycyclic Aromatic Hydrocarbon-induced Pulmonary Carcinogenesis in Cytochrome P450 (CYP)1A1- and 1A2-Null Mice: Roles of CYP1A1 and CYP1A2
2020 · Grady Gastelum, Weiwu Jiang, et al. · Toxicological Sciences · 45
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Molecular role of cytochrome P4501A enzymes in oxidative stress
2020 · Rachel Stading, Chun Chu, et al. · Current Opinion in Toxicology · 84
Pilot-Scale Pyrolytic Remediation of Crude-Oil-Contaminated Soil in a Continuously-Fed Reactor: Treatment Intensity Trade-Offs
2019 · Wen Song, Julia E. Vidonish, et al. · Environmental Science & Technology · 67
Omeprazole induces heme oxygenase-1 in fetal human pulmonary microvascular endothelial cells via hydrogen peroxide-independent Nrf2 signaling pathway
2016 · Ananddeep Patel, Shaojie Zhang, et al. · Toxicology and Applied Pharmacology · 20
Mechanistic role of cytochrome P450 (CYP)1B1 in oxygen-mediated toxicity in pulmonary cells: A novel target for prevention of hyperoxic lung injury
2016 · Daniela Dinu, Chun Chu, et al. · Biochemical and Biophysical Research Communications · 19
Gene Expression Profiling Identifies Cell Proliferation and Inflammation as the Predominant Pathways Regulated by Aryl Hydrocarbon Receptor in Primary Human Fetal Lung Cells Exposed to Hyperoxia
2016 · Binoy Shivanna, Suman Maity, et al. · Toxicological Sciences · 21
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Omeprazole induces NAD(P)H quinone oxidoreductase 1 via aryl hydrocarbon receptor-independent mechanisms: Role of the transcription factor nuclear factor erythroid 2–related factor 2
2015 · Shaojie Zhang, Ananddeep Patel, et al. · Biochemical and Biophysical Research Communications · 6
Leflunomide Induces Pulmonary and Hepatic CYP1A Enzymes via Aryl Hydrocarbon Receptor
2015 · Ananddeep Patel, Shaojie Zhang, et al. · Drug Metabolism and Disposition · 9
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Can maternal DHA supplementation offer long-term protection against neonatal hyperoxic lung injury?
2015 · Krithika Lingappan, Bhagavatula Moorthy · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2
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Omeprazole Attenuates Pulmonary Aryl Hydrocarbon Receptor Activation and Potentiates Hyperoxia-Induced Developmental Lung Injury in Newborn Mice
2015 · Binoy Shivanna, Shaojie Zhang, et al. · Toxicological Sciences · 25
Adrenomedullin deficiency potentiates hyperoxic injury in fetal human pulmonary microvascular endothelial cells
2015 · Shaojie Zhang, Ananddeep Patel, et al. · Biochemical and Biophysical Research Communications · 18
Role of GDF15 (growth and differentiation factor 15) in pulmonary oxygen toxicity
2015 · Kirti Kumar Tiwari, Bhagavatula Moorthy, et al. · Toxicology in Vitro · 35
Detection of Bulky Endogenous Oxidative DNA Lesions Derived from 8,5′‐Cyclo‐2′‐deoxyadenosine by 32P‐Postlabeling Assay
2015 · Guo‐Dong Zhou, Bhagavatula Moorthy · Current Protocols in Toxicology · 6
Polycyclic Aromatic Hydrocarbons: From Metabolism to Lung Cancer
2015 · Bhagavatula Moorthy, Chun Chu, et al. · Toxicological Sciences · 801
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Aryl hydrocarbon receptor is necessary to protect fetal human pulmonary microvascular endothelial cells against hyperoxic injury: Mechanistic roles of antioxidant enzymes and RelB
2015 · Shaojie Zhang, Ananddeep Patel, et al. · Toxicology and Applied Pharmacology · 49
Sex-specific differences in hyperoxic lung injury in mice: Role of cytochrome P450 (CYP)1A
2015 · Krithika Lingappan, Weiwu Jiang, et al. · Toxicology · 36
Disruption of cytochrome P4501A2 in mice leads to increased susceptibility to hyperoxic lung injury
2015 · Lihua Wang, Krithika Lingappan, et al. · Free Radical Biology and Medicine · 40
Omeprazole does not Potentiate Acute Oxygen Toxicity in Fetal Human Pulmonary Microvascular Endothelial Cells Exposed to Hyperoxia
2015 · Ananddeep Patel, Shaojie Zhang, et al. · Pharmaceutica Analytica Acta · 6
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Analysis of the Transcriptome in Hyperoxic Lung Injury and Sex-Specific Alterations in Gene Expression
2014 · Krithika Lingappan, Chandra Srinivasan, et al. · PLoS ONE · 34
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Differential concentration-specific effects of caffeine on cell viability, oxidative stress, and cell cycle in pulmonary oxygen toxicity in vitro
2014 · Kirti Kumar Tiwari, Chun Chu, et al. · Biochemical and Biophysical Research Communications · 59
Mechanistic relationships between hepatic genotoxicity and carcinogenicity in male B6C3F1 mice treated with polycyclic aromatic hydrocarbon mixtures
2014 · Tracie D. Phillips, Molly Richardson, et al. · Archives of Toxicology · 32
Increased susceptibility to hyperoxic lung injury and alveolar simplification in newborn rats by prenatal administration of benzo[a]pyrene
2014 · Vijay S. Thakur, Yanhong W. Liang, et al. · Toxicology Letters · 38
Sex-specific differences in hyperoxic lung injury in mice: Implications for acute and chronic lung disease in humans
2013 · Krithika Lingappan, Weiwu Jiang, et al. · Toxicology and Applied Pharmacology · 55
Functional deficiency of aryl hydrocarbon receptor augments oxygen toxicity-induced alveolar simplification in newborn mice
2013 · Binoy Shivanna, Wenyan Zhang, et al. · Toxicology and Applied Pharmacology · 36
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