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201592

Funded outputs count: 16
Funder award ID: 201592
OpenAlex ID: G1954209652
The mTOR Targets 4E-BP1/2 Restrain Tumor Growth and Promote Hypoxia Tolerance in PTEN-driven Prostate Cancer
2018 · Mei Ding, Theodorus H. Van der Kwast, et al. · Molecular Cancer Research · 31
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Development of TRACER: tissue roll for analysis of cellular environment and response
2016 · Darren Rodenhizer, Dan Cojocari, et al. · Biofabrication · 31
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A three-dimensional engineered tumour for spatial snapshot analysis of cell metabolism and phenotype in hypoxic gradients
2015 · Darren Rodenhizer, Edoardo Gaude, et al. · Nature Materials · 131
Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs
2015 · Francis W. Hunter, Richard J. Young, et al. · Cancer Research · 83
Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression
2014 · Rajesha Rupaimoole, Sherry Y. Wu, et al. · Nature Communications · 183
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Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER
2014 · Twan van den Beucken, Elizabeth Koch, et al. · Nature Communications · 229
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Hypoxia Signaling and the Metastatic Phenotype
2014 · H. Mujcic, R.P. Hill, et al. · Current Molecular Medicine · 30
The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress
2014 · Peter van Galen, Antonija Kreso, et al. · Nature · 379
Post-transcriptional regulation of MRE11 expression in muscle-invasive bladder tumours
2014 · Rebecca M. Martin, Martin Kerr, et al. · Oncotarget · 13
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Hypoxic Activation of the PERK/eIF2α Arm of the Unfolded Protein Response Promotes Metastasis through Induction of LAMP3
2013 · Hilda Mujcic, Anika Nagelkerke, et al. · Clinical Cancer Research · 130
PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS
2013 · Kasper M. Rouschop, Ludwig J. Dubois, et al. · Proceedings of the National Academy of Sciences · 225
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The prognostic value of temporal in vitro and in vivo derived hypoxia gene-expression signatures in breast cancer
2012 · Maud H.W. Starmans, Kenneth C. Chu, et al. · Radiotherapy and Oncology · 49
Hypoxia disrupts the Fanconi anemia pathway and sensitizes cells to chemotherapy through regulation of UBE2T
2011 · Chantal H.M.A. Ramaekers, Twan van den Beucken, et al. · Radiotherapy and Oncology · 39
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Deregulation of cap-dependent mRNA translation increases tumour radiosensitivity through reduction of the hypoxic fraction
2011 · Kasper M.A. Rouschop, Ludwig Dubois, et al. · Radiotherapy and Oncology · 23
Translational control is a major contributor to hypoxia induced gene expression
2011 · Twan van den Beucken, Michael G. Magagnin, et al. · Radiotherapy and Oncology · 47
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AMPK regulates metabolism and survival in response to ionizing radiation
2011 · Vanessa E. Zannella, Dan Cojocari, et al. · Radiotherapy and Oncology · 68
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