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30772629

Field: Medicine
Funded outputs count: 23
Funder award ID: 30772629
OpenAlex ID: G1985353151
Structural optimization of pyridine-type DAPY derivatives to exploit the tolerant regions of the NNRTI binding pocket
2016 · Wenmin Chen, Peng Zhan, et al. · European Journal of Medicinal Chemistry · 33
Clinical Characteristics and Prognosis of 167 Cases of Acute Erythroleukemia
2016 · Zhi-qiang Ma, Ji-hong Pan, et al. · Indian Journal of Hematology and Blood Transfusion · 3
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3D-QSAR and docking studies on piperidine-substituted diarylpyrimidine analogues as HIV-1 reverse transcriptase inhibitors
2015 · Xin Liu, Xuwang Chen, et al. · Medicinal Chemistry Research · 14
Recent Advance of the Hepatitis B Virus Inhibitors: A Medicinal Chemistry Overview
2015 · Haiyong Jia, Diwakar Rai, et al. · Future Medicinal Chemistry · 24
Design, Synthesis, and Anti‐ HIV Evaluation of Novel Triazine Derivatives Targeting the Entrance Channel of the NNRTI Binding Pocket
2014 · Xuwang Chen, Qing Meng, et al. · Chemical Biology & Drug Design · 23
Design, synthesis and anti-HIV evaluation of novel diarylnicotinamide derivatives (DANAs) targeting the entrance channel of the NNRTI binding pocket through structure-guided molecular hybridization
2014 · Zhaoqiang Liu, Wenmin Chen, et al. · European Journal of Medicinal Chemistry · 42
Synthesis and Anti‐ HIV Activity of 4‐(Naphthalen‐1‐yl)‐1,2,5‐thiadiazol‐3‐hydroxyl Derivatives
2014 · Diwakar Rai, Wenmin Chen, et al. · Chemical Biology & Drug Design · 24
Fused heterocyclic compounds bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 1: Design, synthesis and biological evaluation of novel 5,7-disubstituted pyrazolo[1,5-a]pyrimidine derivatives
2014 · Ye Tian, Deping Du, et al. · Bioorganic & Medicinal Chemistry · 91
Discovery of 2-pyridone derivatives as potent HIV-1 NNRTIs using molecular hybridization based on crystallographic overlays
2014 · Wenmin Chen, Peng Zhan, et al. · Bioorganic & Medicinal Chemistry · 47
Design, synthesis and preliminary SAR studies of novel N-arylmethyl substituted piperidine-linked aniline derivatives as potent HIV-1 NNRTIs
2013 · Lingzi Zhang, Peng Zhan, et al. · Bioorganic & Medicinal Chemistry · 21
Novel piperidinylamino-diarylpyrimidine derivatives with dual structural conformations as potent HIV-1 non-nucleoside reverse transcriptase inhibitors
2013 · Xuwang Chen, Xin Liu, et al. · Bioorganic & Medicinal Chemistry Letters · 24
Design, synthesis and biological evaluation of 3-benzyloxy-linked pyrimidinylphenylamine derivatives as potent HIV-1 NNRTIs
2013 · Diwakar Rai, Wenmin Chen, et al. · Bioorganic & Medicinal Chemistry · 13
Design, synthesis and biological evaluation of N2,N4-disubstituted-1,1,3-trioxo-2H,4H-pyrrolo[1,2-b][1,2,4,6]thiatriazine derivatives as HIV-1 NNRTIs
2013 · Wenmin Chen, Peng Zhan, et al. · Bioorganic & Medicinal Chemistry · 12
Design, Synthesis, and Biological Evaluation of Novel 3,5‐Disubstituted‐1,2,6‐Thiadiazine‐1,1‐Dione Derivatives as HIV ‐1 NNRTI s
2013 · Ye Tian, Diwakar Rai, et al. · Chemical Biology & Drug Design · 7
Synthesis and biological evaluation of pyridazine derivatives as novel HIV-1 NNRTIs
2013 · Dongyue Li, Peng Zhan, et al. · Bioorganic & Medicinal Chemistry · 61
Discovery of novel pyridazinylthioacetamides as potent HIV-1 NNRTIs using a structure-based bioisosterism approach
2013 · Yu’ning Song, Peng Zhan, et al. · MedChemComm · 8
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Design, synthesis, anti-HIV evaluation and molecular modeling of piperidine-linked amino-triazine derivatives as potent non-nucleoside reverse transcriptase inhibitors
2012 · Xuwang Chen, Peng Zhan, et al. · Bioorganic & Medicinal Chemistry · 72
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Synthesis and Preliminary Biologic Evaluation of 5‐Substituted‐2‐(4‐substituted phenyl)‐1,3‐Benzoxazoles as A Novel Class of Influenza Virus A Inhibitors
2012 · Zhenyu Li, Peng Zhan, et al. · Chemical Biology & Drug Design · 9
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Discovery of Dihydro‐Alkyloxy‐Benzyl‐Oxopyrimidines as Promising Anti‐Influenza Virus Agents
2011 · Mingyan Yu, Ailin Liu, et al. · Chemical Biology & Drug Design · 8
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Synthesis and biological evaluation of novel 5-alkyl-2-arylthio-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors
2011 · Jing Zhang, Peng Zhan, et al. · Bioorganic & Medicinal Chemistry · 39
Synthesis and anti-HIV activity of novel 2,4-disubstituted-7-methyl-1,1,3-trioxo-2H,4H-pyrazolo[4,5-e][1,2,4]thiadiazine derivatives
2011 · Peng Zhan · Drug Discoveries & Therapeutics · 2
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Synthesis and anti-HIV activity evaluation of novel N′-arylidene-2-[1-(naphthalen-1-yl)-1H-tetrazol-5-ylthio]acetohydrazides
2009 · Peng Zhan, Hongbing Liu, et al. · Medicinal Chemistry Research · 30
Synthesis and anti-HIV evaluation of novel 1,3-disubstituted thieno[3,2-c][1,2,6]thiadiazin-4(3H)-one 2,2-dioxides(TTDDs)
2007 · Yongqiang Lin, Xinyong Liu, et al. · Bioorganic & Medicinal Chemistry · 11
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