Award

The Bone Trial of the Testosterone Trial

Description: The significance of The Bone Trial is that it would be the first study to assess the effect of testosterone on volumetric BMD in men >65 with low testosterone and, more importantly, the first to assess the effect of testosterone on bone strength in these men. Demonstration that testosterone could improve bone strength in these men would be a major impetus to a long-term trial to determine if testosterone treatment would reduce clinical fractures as well. The Bone Trial could therefore be the first major step in determining if testosterone treatment could ameliorate the increasing public health burden of fractures in older men.
Funding type: research
Funder scheme: R01
Start date: 2011-09-01
End date: 2017-05-31
Field: Medicine
Funded outputs count: 12
Funder award ID: R01AG037679
OpenAlex ID: G2425252908
2020 · Ronald Swerdloff, Christina Wang · Andrology · 12
2019 · Glenn R Cunningham, Susan S Ellenberg, et al. · The Journal of Clinical Endocrinology & Metabolism · 29
2018 · Peter J Snyder, Shalender Bhasin, et al. · Endocrine Reviews · 285
2017 · Emile R Mohler, Susan S Ellenberg, et al. · The Journal of Clinical Endocrinology & Metabolism · 119
2016 · Peter J. Snyder, Shalender Bhasin, et al. · New England Journal of Medicine · 930
2015 · Jane A. Cauley, Laura Fluharty, et al. · The Journals of Gerontology Series A · 31
2014 · Peter J Snyder, Susan S Ellenberg, et al. · Clinical Trials · 117