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29754

Funded outputs count: 13
Funder award ID: 29754
OpenAlex ID: G3290580326
RNF213 M1-ubiquitinates damaged mitochondria to activate pro-inflammatory NF-κB signaling
2026 · Rosalie Heilig, Hannah Glover, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Nutrient-sensitizing drug repurposing screen identifies lomerizine as a mitochondrial metabolism inhibitor of chronic myeloid leukemia
2024 · Ahmed Khalaf, Lucie de Beauchamp, et al. · Science Translational Medicine · 11
Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche
2024 · Amy Dawson, Martha M. Zarou, et al. · Nature Communications · 11
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Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells
2023 · Kevin M. Rattigan, Zuzana Brabcova, et al. · Nature Communications · 26
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Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells
2023 · Kevin M Rattigan, Martha M Zarou, et al. · EMBO Reports · 7
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Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death
2023 · Keith Woodley, Laura S. Dillingh, et al. · Nature Communications · 30
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Metabolism in stem cell driven leukaemia: parallels between haematopoiesis and immunity
2023 · Kevin M. Rattigan, Martha M. Zarou, et al. · Blood · 16
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Targeting ULK1 in cancer stem cells: insight from chronic myeloid leukemia
2022 · Angela Ianniciello, G. Vignir Helgason · Autophagy · 16
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ULK1 inhibition promotes oxidative stress–induced differentiation and sensitizes leukemic stem cells to targeted therapy
2021 · Angela Ianniciello, Martha M. Zarou, et al. · Science Translational Medicine · 54
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Mitochondrial metabolism as a potential therapeutic target in myeloid leukaemia
2021 · Lucie de Beauchamp, Ekaterini Himonas, et al. · Leukemia · 168
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Folate metabolism: a re-emerging therapeutic target in haematological cancers
2021 · Martha M. Zarou, Alexei Vazquez, et al. · Leukemia · 120
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1
2021 · Daniel J. Klionsky, Amal Kamal Abdel-Aziz, et al. · Autophagy · 2,812
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The leukaemia stem cell: similarities, differences and clinical prospects in CML and AML
2020 · David Vetrie, G. Vignir Helgason, et al. · Nature reviews. Cancer · 351
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