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U54CA193461

Funded outputs count: 100
Funder award ID: U54CA193461
OpenAlex ID: G3352250835
A mitochondrial NADPH-cholesterol axis regulates extracellular vesicle biogenesis to support hematopoietic stem cell fate
2024 · Massimo Bonora, Claudia Morganti, et al. · Cell stem cell · 65
Heterogeneity and transcriptional drivers of triple-negative breast cancer
2023 · Bojana Jovanović, Daniel Temko, et al. · Cell Reports · 34
Mathematical Modeling Identifies Optimum Palbociclib-fulvestrant Dose Administration Schedules for the Treatment of Patients with Estrogen Receptor–positive Breast Cancer
2023 · Yu-Chen Cheng, Shayna Stein, et al. · Cancer Research Communications · 8
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H3K36 methylation maintains cell identity by regulating opposing lineage programmes
2023 · Michael S. Hoetker, Masaki Yagi, et al. · Nature Cell Biology · 45
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Production of an interleukin-10 blocking antibody by genetically engineered macrophages increases cancer cell death in human gastrointestinal tumor slice cultures
2023 · Kevin P. Labadie, Shannon A. Kreuser, et al. · Cancer Gene Therapy · 6
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Visualizing genomic characteristics across an RNA-Seq based reference landscape of normal and neoplastic brain
2023 · Sonali Arora, Frank Szulzewsky, et al. · Scientific Reports · 10
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Breast cancer prevention by short-term inhibition of TGFβ signaling
2022 · Maša Alečković, Simona Cristea, et al. · Nature Communications · 14
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Phase I study of a novel glioblastoma radiation therapy schedule exploiting cell-state plasticity
2022 · Jamie A Dean, Shyam K Tanguturi, et al. · Neuro-Oncology · 14
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Oncogenic role of a developmentally regulated NTRK2 splice variant
2022 · Siobhan S. Pattwell, Sonali Arora, et al. · Science Advances · 7
Spatial intra-tumor heterogeneity is associated with survival of lung adenocarcinoma patients
2022 · Hua-Jun Wu, Daniel Temko, et al. · Cell Genomics · 53
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Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer
2022 · Emily S. Bell, Pragya Shah, et al. · Oncogene · 126
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In vivo genome-wide CRISPR screening in murine acute myeloid leukemia uncovers microenvironmental dependencies
2022 · Francois E. Mercier, Jiantao Shi, et al. · Blood Advances · 20
Designing optimal allocations for cancer screening using queuing network models
2022 · Justin Dean, Evan Goldberg, et al. · PLoS Computational Biology · 3
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Barcoded bulk QTL mapping reveals highly polygenic and epistatic architecture of complex traits in yeast
2022 · Alex N. Nguyen Ba, Katherine R. Lawrence, et al. · eLife · 70
Astrocytic laminin-211 drives disseminated breast tumor cell dormancy in brain
2021 · Jinxiang Dai, Patrick J. Cimino, et al. · Nature Cancer · 135
Transcriptional differences between JAK2-V617F and wild-type bone marrow cells in patients with myeloproliferative neoplasms
2021 · Debra Van Egeren, Baransel Kamaz, et al. · Experimental Hematology · 21
What is the role of the bone marrow microenvironment in AML?
2021 · Nirupama Mulherkar, David T. Scadden · Best Practice & Research Clinical Haematology · 5
Proton export alkalinizes intracellular pH and reprograms carbon metabolism to drive normal and malignant cell growth
2021 · Cheuk Him Man, Francois E. Mercier, et al. · Blood · 45
Dissecting dual roles of MyoD during lineage conversion to mature myocytes and myogenic stem cells
2021 · Masaki Yagi, Fei Ji, et al. · Genes & Development · 47
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Topological isolation of developmental regulators in mammalian genomes
2021 · Hua-Jun Wu, Alexandro Landshammer, et al. · Nature Communications · 29
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Identification of optimal dosing schedules of dacomitinib and osimertinib for a phase I/II trial in advanced EGFR-mutant non-small cell lung cancer
2021 · Kamrine E. Poels, Adam J. Schoenfeld, et al. · Nature Communications · 33
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Combined epigenetic and metabolic treatments overcome differentiation blockade in acute myeloid leukemia
2021 · Barry M. Zee, Kamrine E. Poels, et al. · iScience · 9
Thorny ground, rocky soil: Tissue-specific mechanisms of tumor dormancy and relapse
2021 · Andrea R. Lim, Cyrus M. Ghajar · Seminars in Cancer Biology · 35
Impact of HER2 Heterogeneity on Treatment Response of Early-Stage HER2-Positive Breast Cancer: Phase II Neoadjuvant Clinical Trial of T-DM1 Combined with Pertuzumab
2021 · Otto Metzger Filho, Giuseppe Viale, et al. · Cancer Discovery · 253
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The impact of tumor epithelial and microenvironmental heterogeneity on treatment responses in HER2+ breast cancer
2021 · Michalina Janiszewska, Shayna Stein, et al. · JCI Insight · 39
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