Harnessing MAIT cells as the next frontier of solid tumour immunotherapy
Description: There is great potential for Mucosal-Associated Invariant T (MAIT) cells to overcome current obstacles impeding conventional T cell immunotherapies, where MAIT cells can be exploited to target solid tumours in a safe, universal manner unrestricted by donor and recipient mismatch. This proposal combines our cutting-edge knowledge and data on MAIT cell biology, T cell engineering, and new nanobody production techniques to generate novel, efficacious MAIT cell therapies in cancer.
Amount: A$970,600
Funding type: research
Funder scheme: Ideas Grants - 2023 Ideas Grants
Investigator: Hui-Fern Koay
Institution: University of Melbourne
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Funded outputs count: 2
Funder award ID: 2030162
OpenAlex ID: G3381654792