Get started
Award

CA68262

Funded outputs count: 29
Funder award ID: CA68262
OpenAlex ID: G3443599876
Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1
2015 · Naotaka Sekiyama, Haribabu Arthanari, et al. · Proceedings of the National Academy of Sciences · 109
PDF
Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G
2014 · Evangelos Papadopoulos, Simon Jenni, et al. · Proceedings of the National Academy of Sciences · 91
1H, 13C, and 15N backbone and sidechain chemical shift assignments for the HEAT2 domain of human eIF4GI
2014 · Katherine A. Edmonds, Gerhard Wagner · Biomolecular NMR Assignments
The Interaction between Eukaryotic Initiation Factor 1A and eIF5 Retains eIF1 within Scanning Preinitiation Complexes
2013 · Rafael E. Luna, Haribabu Arthanari, et al. · Biochemistry · 44
PDF
The C-Terminal Domain of Eukaryotic Initiation Factor 5 Promotes Start Codon Recognition by Its Dynamic Interplay with eIF1 and eIF2β
2012 · Rafael E. Luna, Haribabu Arthanari, et al. · Cell Reports · 72
PDF
Evolutionary changes in the Leishmania eIF4F complex involve variations in the eIF4E–eIF4G interactions
2009 · Yael Yoffe, Mélissa Léger, et al. · Nucleic Acids Research · 66
PDF
Topology and Regulation of the Human eIF4A/4G/4H Helicase Complex in Translation Initiation
2009 · Assen Marintchev, Katherine A. Edmonds, et al. · Cell · 224
PDF
PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains
2008 · Chikako Suzuki, Robert G. Garces, et al. · Proceedings of the National Academy of Sciences · 165
Selective Pharmacological Targeting of a DEAD Box RNA Helicase
2008 · Lisa Lindqvist, Monika Oberer, et al. · PLoS ONE · 132
PDF
Eukaryotic Initiation Factor (eIF) 1 Carries Two Distinct eIF5-binding Faces Important for Multifactor Assembly and AUG Selection
2007 · Mikhail Reibarkh, Yasufumi Yamamoto, et al. · Journal of Biological Chemistry · 67
Sequence and structure evolved separately in a ribosomal ubiquitin variant
2007 · André Catic, Zhen‐Yu J Sun, et al. · The EMBO Journal · 27
PDF
Small-Molecule Inhibition of the Interaction between the Translation Initiation Factors eIF4E and eIF4G
2007 · Nathan J. Moerke, Huseyin Aktas, et al. · Cell · 572
PDF
Resonance assignments of the α subunit of human eukaryotic initiation factor 2 (heIF2α)
2006 · Takuhiro Ito, Gerhard Wagner · Journal of Biomolecular NMR
Mapping of the Auto-inhibitory Interactions of Protein Kinase R by Nuclear Magnetic Resonance
2006 · Vladimir Gelev, Huseyin Aktas, et al. · Journal of Molecular Biology · 34
Folding Transitions During Assembly of the Eukaryotic mRNA Cap-binding Complex
2005 · Tobias von der Haar, Yuko Oku, et al. · Journal of Molecular Biology · 36
PDF
Structural basis for the enhancement of eIF4A helicase activity by eIF4G
2005 · Monika Oberer, Assen Marintchev, et al. · Genes & Development · 167
PDF
eIF4G and CBP80 Share a Common Origin and Similar Domain Organization: Implications for the Structure and Function of eIF4G
2005 · Assen Marintchev, Gerhard Wagner · Biochemistry · 61
Multiple Conformations in the Ligand-binding Site of the Yeast Nuclear Pore-targeting Domain of Nup116p
2005 · Michael A. Robinson, Sunghyouk Park, et al. · Journal of Biological Chemistry · 19
Translation initiation: structures, mechanisms and evolution
2004 · Assen Marintchev, Gerhard Wagner · Quarterly Reviews of Biophysics · 223
Solution Structure of Human Initiation Factor eIF2α Reveals Homology to the Elongation Factor eEF1B
2004 · Takuhiro Ito, Assen Marintchev, et al. · Structure · 80
PDF
The mRNA cap-binding protein eIF4E in post-transcriptional gene expression
2004 · Tobias von der Haar, John D Gross, et al. · Nature Structural & Molecular Biology · 233
PDF
Using codon optimization, chaperone co-expression, and rational mutagenesis for production and NMR assignments of human eIF2α
2004 · Takuhiro Ito, Gerhard Wagner · Journal of Biomolecular NMR · 29
Ribosome Loading onto the mRNA Cap Is Driven by Conformational Coupling between eIF4G and eIF4E
2003 · John D. Gross, Nathan J. Moerke, et al. · Cell · 346
PDF
A sensitive and robust method for obtaining intermolecular NOEs between side chains in large protein complexes
2003 · John D. Gross, Vladimir M. Gelev, et al. · Journal of Biomolecular NMR · 71
The eIF1A Solution Structure Reveals a Large RNA-Binding Surface Important for Scanning Function
2000 · John L. Battiste, Tatyana V. Pestova, et al. · Molecular Cell · 178
PDF
Year
Topic