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pHLIP Nanotechnology Platform for Cancer Imaging and Therapy

Funding type: research
Funder scheme: R01
Start date: 2008-07-01
End date: 2014-08-31
Investigator: OLEG A ANDREEV
Institution: UNIVERSITY OF RHODE ISLAND
Funded outputs count: 35
Funder award ID: R01CA133890
OpenAlex ID: G3444298528
Ex-vivo Imaging of Upper Tract Urothelial Carcinoma Using Novel pH Low Insertion Peptide (Variant 3), a Molecular Imaging Probe
2019 · Joseph Brito, Borivoj Golijanin, et al. · Urology · 18
Use of Radiation to Kill Cancer by Nanoparticles and in a Biodosimeter Using Gene Expression Analysis
2018 · Shrestha, Samana
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Design and Development of pH Sensitive Nanomedicine for Targeted Drug Delivery
2016 · Pereira, Mohan C.
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The pH low insertion peptide pHLIP Variant 3 as a novel marker of acidic malignant lesions
2015 · Thomas T. Tapmeier, Anna Moshnikova, et al. · Proceedings of the National Academy of Sciences · 67
Enhancement of radiation effect on cancer cells by gold-pHLIP
2015 · Michael P. Antosh, Dayanjali D. Wijesinghe, et al. · Proceedings of the National Academy of Sciences · 95
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Advanced targeted nanomedicine
2015 · Mohan C.M. Arachchige, Yana K. Reshetnyak, et al. · Journal of Biotechnology · 67
Design and Development of pH-Sensitive Peptides for Cancer Diagnostics
2015 · Adochite, Ramona Cosmina
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pHLIP-FIRE, a Cell Insertion-Triggered Fluorescent Probe for Imaging Tumors Demonstrates Targeted Cargo Delivery In Vivo
2014 · Alexander G. Karabadzhak, Ming An, et al. · ACS Chemical Biology · 32
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Targeting Breast Tumors with pH (Low) Insertion Peptides
2014 · Ramona-Cosmina Adochite, Anna Moshnikova, et al. · Molecular Pharmaceutics · 73
Targeting Pancreatic Ductal Adenocarcinoma Acidic Microenvironment
2014 · Zobeida Cruz-Monserrate, Christina L. Roland, et al. · Scientific Reports · 94
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Targeting diseased tissues by pHLIP insertion at low cell surface pH
2014 · Oleg A. Andreev, Donald M. Engelman, et al. · Frontiers in Physiology · 98
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pH dependent transfer of nano-pores into membrane of cancer cells to induce apoptosis
2013 · Dayanjali Wijesinghe, Mohan C. M. Arachchige, et al. · Scientific Reports · 51
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Aspartate Embedding Depth Affects pHLIP’s Insertion pKa
2013 · Justin Fendos, Francisco N. Barrera, et al. · Biochemistry · 50
Family of pH (low) insertion peptides for tumor targeting
2013 · Dhammika Weerakkody, Anna Moshnikova, et al. · Proceedings of the National Academy of Sciences · 207
pHLIP®-mediated delivery of PEGylated liposomes to cancer cells
2013 · Lan Yao, Jennifer Daniels, et al. · Journal of Controlled Release · 93
Antiproliferative Effect of pHLIP-Amanitin
2013 · Anna Moshnikova, Valentina Moshnikova, et al. · Biochemistry · 80
pHLIP peptide targets nanogold particles to tumors
2012 · Lan Yao, Jennifer Daniels, et al. · Proceedings of the National Academy of Sciences · 155
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pH (low) insertion peptide (pHLIP) targets ischemic myocardium
2012 · Eugene A. Sosunov, Evgeny P. Anyukhovsky, et al. · Proceedings of the National Academy of Sciences · 77
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Membrane physical properties influence transmembrane helix formation
2012 · Francisco N. Barrera, Justin Fendos, et al. · Proceedings of the National Academy of Sciences · 82
Modulation of the pHLIP Transmembrane Helix Insertion Pathway
2012 · Alexander G. Karabadzhak, Dhammika Weerakkody, et al. · Biophysical Journal · 67
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In Vivo pH Imaging with 99mTc-pHLIP
2012 · Sven Macholl, Matthew S. Morrison, et al. · Molecular Imaging and Biology · 69
Tuning a Polar Molecule for Selective Cytoplasmic Delivery by a pH (Low) Insertion Peptide
2011 · Dayanjali Wijesinghe, Donald M. Engelman, et al. · Biochemistry · 52
Roles of Carboxyl Groups in the Transmembrane Insertion of Peptides
2011 · Francisco N. Barrera, Dhammika Weerakkody, et al. · Journal of Molecular Biology · 76
Thrombopoietin receptor activation: transmembrane helix dimerization, rotation, and allosteric modulation
2011 · Erin E. Matthews, Damien Thévenin, et al. · The FASEB Journal · 76
SELECTIVE TRANSLOCATION OF CELL-IMPERMEABLE TOXINS INTO CANCER CELLS: pHLIP MEDIATED DELIVERY OF PHALLOTOXINS INHIBITS CANCER PROLIFERATION
2011 · Wijesinghe, Dayanjali Diluka
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