Dendritic Cell Vaccine for Controlling the Latent Reservoir
Description: PUBLIC HEALTH RELEVANCE: HIV-1 infected individuals treated with a combination of antiretroviral drugs maintain a very small amount of the virus in their blood and thus are not cured, even after years of treatment. The inability to cure an infected person is caused by rare, long-lived cells that harbor the virus in a dormant state. The project aims to develop a vaccine that will stimulate an infected person's immune system to get rid of the cells that harbor the dormant virus, ultimately curing the person of the infection such that they can stop taking the drugs without having the virus return.
Funding type: research
Funder scheme: R21
Start date: 2015-12-01
End date: 2018-01-08
Investigator: HANS-PETER KIEM
Institution: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
Funded outputs count: 27
Funder award ID: R21AI122390
OpenAlex ID: G3579110949