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The developement for effectiveness of rehabilitation in obstructive sleep apnea

Description: Although tongue protrusion strength by genioglossus activity during sleep contributes to the maintenance of airway patency in patients with OSA, the relationship between tongue protrusion strength in the arousal state and obstructive sleep apnea has not been fully elucidated. We investigated relationships between the tongue protrusion strength and polysomnographic findings. We enrolled twenty normal subjects and 26 subjects with OSA. All subjects completed the measurement of tongue protrusion strength. Each subject with OSA was evaluated by full polysomnography. The degree of tongue protrusion strength was assessed by maximum voluntary contraction against the tongue depressor connected with a strain gauge dynamometer. The tongue protrusion strength was negatively correlated with obstructive apnea time, apnea index (AI) and the percent of sleep stage 2. Tongue protrusion strength measured in the arousal state is predictive of the airway patency during sleep in OSA.

Funder: Japan Society for the Promotion of Science

Amount: ¥3,640,000

Funding type: fellowship

Funder scheme: Grant-in-Aid for Young Scientists (B)

Start date: 2014-04-01

End date: 2016-03-31

Investigator: Masashi Kanezaki (lead)

Institution: Himeji Dokkyo University

Topic: Obstructive Sleep Apnea Research

Subfield: Physiology (medical)

Field: Medicine

Domain: Health Sciences