Preliminary experiment for the application of MR elastography for non invasive measurement of intracranial environment
Description: The purpose of present study is to develop novel minimally invasive method to monitor intracranial pressure, intracranial compliance, and cerebral autoregulation by applying magnetic resonance elastotraphy MRE)technique, which is emerging application of magnetic resonance imaging (MRI).The basic experiments for imaging by MRE were conducted using animal traumatic brain injury (TBI) model with known mechanical characteristics. In addition, database for mechanical property (breaking strength and Young's modulus) was developed in both animal model (swine) and human, which would facilitate to validate the data in the future application of MRE.
Amount: ¥3,770,000
Funding type: research
Funder scheme: Grant-in-Aid for Challenging Exploratory Research
Investigator: Atsuhiro NAKAGAWA (lead)
Institution: Tohoku University
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Funded outputs count: 4
Funder award ID: 23659680
OpenAlex ID: G4024254012