Award

Suppression of Treg Recruitment in Cancer Immunotherapy: Tick Evasins as Chemokine-targeted Therapeutics

Description: A major advance in cancer treatment has been the use of immunotherapy, which promotes the patient’s own immune defences against the tumour. However, some tumours are resistant to immunotherapy. In this project, we will test a novel strategy to overcome this resistance and enable effective tumour elimination.

Funder: National Health and Medical Research Council

Amount: A$1,058,000

Funding type: research

Funder scheme: Ideas Grants - 2024 Ideas Grants

Investigator: Martin Stone

Institution: Monash University

Funded outputs count: 3

Funder award ID: 2036762

OpenAlex ID: G4064308989

Principles for the design of multispecific proteins

2026 · Shankar Raj Devkota, Pramod Aryal, et al. · Trends in Biochemical Sciences · 1

Discovery of an evolutionarily distinct evasin with dual CC and CXC chemokine inhibitory activity

2026 · Surendra Kunwar, Shankar Raj Devkota, et al. · Structure · 1

Engineering Tick Evasins as Multitarget Chemokine Inhibitors─A Biomimetic Approach To Tackling the Complexity of the Immune System

2026 · Levi J. Naunton, Pramish Mainali, et al. · Accounts of Chemical Research · 2