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乙型肝炎病毒x蛋白激活Rho信号途径诱发肝细胞恶性转化分子机制的定量蛋白质组学研究

Amount: ¥850,000
Funding type: grant
Funder scheme: 面上项目
Start date: 2014-01-01
End date: 2018-12-31
Investigator: 平 徐
Institution: 中国人民解放军军事科学院军事医学研究院
Funded outputs count: 27
Funder award ID: 31470809
OpenAlex ID: G4079110445
Recombinant expression, purification and characterization of acetylated LysargiNase from Escherichia coli with high activity and stability
2019 · Junling Zhang, Mingzhi Zhao, et al. · Rapid Communications in Mass Spectrometry · 11
Quantitative proteomics reveals mitochondrial respiratory chain as a dominant target for carbon ion radiation: Delayed reactive oxygen species generation caused DNA damage
2018 · Peng-Cheng Fan, Yao Zhang, et al. · Free Radical Biology and Medicine · 37
Multiproteases Combined with High-pH Reverse-Phase Separation Strategy Verified Fourteen Missing Proteins in Human Testis Tissue
2018 · Jinshuai Sun, Jiahui Shi, et al. · Journal of Proteome Research · 20
Digging for Missing Proteins Using Low-Molecular-Weight Protein Enrichment and a “Mirror Protease” Strategy
2018 · Cuitong He, Jinshuai Sun, et al. · Journal of Proteome Research · 16
Enrichment-Based Proteogenomics Identifies Microproteins, Missing Proteins, and Novel smORFs in Saccharomyces cerevisiae
2018 · Cuitong He, Chenxi Jia, et al. · Journal of Proteome Research · 48
Proteomic Analysis and NIR-II Imaging of MCM2 Protein in Hepatocellular Carcinoma
2018 · Jing Yang, Qi Xie, et al. · Journal of Proteome Research · 39
Down-regulation of RIP3 potentiates cisplatin chemoresistance by triggering HSP90-ERK pathway mediated DNA repair in esophageal squamous cell carcinoma
2018 · Yulin Sun, Linhui Zhai, et al. · Cancer Letters · 44
Multi-Protease Strategy Identifies Three PE2 Missing Proteins in Human Testis Tissue
2017 · Yihao Wang, Yang Chen, et al. · Journal of Proteome Research · 26
Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer
2017 · Xuehui Peng, Feng Xu, et al. · Journal of Proteome Research · 21
High‐coverage proteomics reveals methionine auxotrophy in Deinococcus radiodurans
2017 · Yanxia Zhou, Pan Shen, et al. · PROTEOMICS · 9
A rapid and easy protein N‐terminal profiling strategy using (N‐Succinimidyloxycarbonylmethyl)tris(2,4,6‐trimethoxyphenyl)phosphonium bromide (TMPP) labeling and StageTip
2017 · Yanchang Li, Zhiqiang Wang, et al. · PROTEOMICS · 17
Hepatitis B Virus X Protein Stimulates Proliferation, Wound Closure and Inhibits Apoptosis of HuH-7 Cells via CDC42
2017 · Yongru Xu, Yingzi Qi, et al. · International Journal of Molecular Sciences · 24
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Multi-omics analyses reveal metabolic alterations regulated by hepatitis B virus core protein in hepatocellular carcinoma cells
2017 · Qi Xie, Fengxu Fan, et al. · Scientific Reports · 59
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iTRAQ-Based Membrane Proteomics Reveals Plasma Membrane Proteins Change During HepaRG Cell Differentiation
2016 · Mingzhi Zhao, Feng Xu, et al. · Journal of Proteome Research · 2
Hepatitis B virus X induces inflammation and cancer in mice liver through dysregulation of cytoskeletal remodeling and lipid metabolism
2016 · Zhongwei Xu, Linghui Zhai, et al. · Oncotarget · 36
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Quantitative proteomics reveals FLNC as a potential progression marker for the development of hepatocellular carcinoma
2016 · Yingzi Qi, Feng Xu, et al. · Oncotarget · 29
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Deep Coverage Proteomics Identifies More Low-Abundance Missing Proteins in Human Testis Tissue with Q-Exactive HF Mass Spectrometer
2016 · Wei Wei, Weijia Luo, et al. · Journal of Proteome Research · 38
Searching Missing Proteins Based on the Optimization of Membrane Protein Enrichment and Digestion Process
2016 · Mingzhi Zhao, Wei Wei, et al. · Journal of Proteome Research · 18
Recombinant expression, refolding, purification and characterization of Pseudomonas aeruginosa protease IV in Escherichia coli
2016 · Mingzhi Zhao, Man Cai, et al. · Protein Expression and Purification · 26
Enhanced Purification of Ubiquitinated Proteins by Engineered Tandem Hybrid Ubiquitin-binding Domains (ThUBDs)
2016 · Yuan Gao, Yanchang Li, et al. · Molecular & Cellular Proteomics · 56
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Development of a rapid high-efficiency scalable process for acetylated Sus scrofa cationic trypsin production from Escherichia coli inclusion bodies
2015 · Mingzhi Zhao, Feilin Wu, et al. · Protein Expression and Purification · 37
(±)-Acortatarinowins A–F, Norlignan, Neolignan, and Lignan Enantiomers from Acorus tatarinowii
2015 · Yuanyuan Lu, Yongbo Xue, et al. · Journal of Natural Products · 72
Tissue-Based Proteogenomics Reveals that Human Testis Endows Plentiful Missing Proteins
2015 · Yao Zhang, Qidan Li, et al. · Journal of Proteome Research · 47
Special Enrichment Strategies Greatly Increase the Efficiency of Missing Proteins Identification from Regular Proteome Samples
2015 · Na Su, Chengpu Zhang, et al. · Journal of Proteome Research · 17
A note on the false discovery rate of novel peptides in proteogenomics
2015 · Kun Zhang, Yan Fu, et al. · Bioinformatics · 34
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