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R01 DK081461

Funded outputs count: 44
Funder award ID: R01 DK081461
OpenAlex ID: G408819899
Expression of cytochrome P450 isozyme transcripts and activities in human livers
2020 · Jie Liu, Yuan-Fu Lu, et al. · Xenobiotica · 57
Sex-, Age-, and Race/Ethnicity-Dependent Variations in Drug-Processing and NRF2-Regulated Genes in Human Livers
2020 · Jie Liu, Julia Yue Cui, et al. · Drug Metabolism and Disposition · 23
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Individual bile acids have differential effects on bile acid signaling in mice
2015 · Peizhen Song, Cheryl E. Rockwell, et al. · Toxicology and Applied Pharmacology · 94
Protection against phalloidin-induced liver injury by oleanolic acid involves Nrf2 activation and suppression of Oatp1b2
2014 · Yuan-Fu Lu, Jie Liu, et al. · Toxicology Letters · 40
Degradation of Keap1 activates BH3-only proteins Bim and PUMA during hepatocyte lipoapoptosis
2014 · S C Cazanave, X Wang, et al. · Cell Death and Differentiation · 48
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Fibroblast growth factor (Fgf) 21 is a novel target gene of the aryl hydrocarbon receptor (AhR)
2014 · Xingguo Cheng, Saurabh G. Vispute, et al. · Toxicology and Applied Pharmacology · 41
Overexpression of Nrf2 Protects against Microcystin-Induced Hepatotoxicity in Mice
2014 · Yuan-Fu Lu, Jie Liu, et al. · PLoS ONE · 33
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Screening of Natural Compounds as Activators of the Keap1-Nrf2 Pathway
2013 · Kai Wu, Peter McDonald, et al. · Planta Medica · 89
Short-term calorie restriction feminizes the mRNA profiles of drug metabolizing enzymes and transporters in livers of mice
2013 · Zidong Donna Fu, Curtis D. Klaassen · Toxicology and Applied Pharmacology · 37
Oleanolic acid alters bile acid metabolism and produces cholestatic liver injury in mice
2013 · Jie Liu, Yuan-Fu Lu, et al. · Toxicology and Applied Pharmacology · 48
Sex Differences in the Circadian Variation of Cytochrome P450 Genes and Corresponding Nuclear Receptors in Mouse Liver
2013 · Yuan-Fu Lu, Tao Jin, et al. · Chronobiology International · 110
Tissue Distribution, Ontogeny, and Chemical Induction of Aldo-Keto Reductases in Mice
2013 · Matthew Pratt-Hyatt, Andrew J. Lickteig, et al. · Drug Metabolism and Disposition · 32
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Genetic Activation of Nrf2 Protects against Fasting-Induced Oxidative Stress in Livers of Mice
2013 · Yu-Kun Jennifer Zhang, Kai Connie Wu, et al. · PLoS ONE · 94
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NRF2 Protection against Liver Injury Produced by Various Hepatotoxicants
2013 · Jie Liu, Kai Connie Wu, et al. · Oxidative Medicine and Cellular Longevity · 148
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Implementation of a High-Throughput Screen for Identifying Small Molecules to Activate the Keap1-Nrf2-ARE Pathway
2012 · Kai Connie Wu, Peter R. McDonald, et al. · PLoS ONE · 40
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Nrf2 deficiency improves glucose tolerance in mice fed a high-fat diet
2012 · Yu-Kun Jennifer Zhang, Kai Connie Wu, et al. · Toxicology and Applied Pharmacology · 93
Effect of Graded Nrf2 Activation on Phase-I and -II Drug Metabolizing Enzymes and Transporters in Mouse Liver
2012 · Kai Connie Wu, Julia Yue Cui, et al. · PLoS ONE · 146
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Nrf2 activation prevents cadmium-induced acute liver injury
2012 · Kai C. Wu, Jie J. Liu, et al. · Toxicology and Applied Pharmacology · 134
Hormonal and Chemical Regulation of Paraoxonases in Mice
2012 · Xingguo Cheng, Curtis D. Klaassen · Journal of Pharmacology and Experimental Therapeutics · 24
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Role of Nrf2 in preventing ethanol-induced oxidative stress and lipid accumulation
2012 · Kai Connie Wu, Jie Liu, et al. · Toxicology and Applied Pharmacology · 150
Coordinated Regulation of Hepatic Phase I and II Drug-Metabolizing Genes and Transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-Null Mice
2012 · Lauren M. Aleksunes, Curtis D. Klaassen · Drug Metabolism and Disposition · 257
Effects of Aging on mRNA Profiles for Drug-Metabolizing Enzymes and Transporters in Livers of Male and Female Mice
2012 · Zidong Donna Fu, Iván L. Csanaky, et al. · Drug Metabolism and Disposition · 80
Gender-Divergent Profile of Bile Acid Homeostasis during Aging of Mice
2012 · Zidong Donna Fu, Iván L. Csanaky, et al. · PLoS ONE · 70
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Bile acids via FXR initiate the expression of major transporters involved in the enterohepatic circulation of bile acids in newborn mice
2012 · Julia Yue Cui, Lauren M. Aleksunes, et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 59
Th2 Skewing by Activation of Nrf2 in CD4+ T Cells
2012 · Cheryl E Rockwell, Mingcai Zhang, et al. · The Journal of Immunology · 131
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