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Hr0011- 17-2-0043
Funder:
Defense Advanced Research Projects Agency
Funded outputs count:
22
Funder award ID:
HR0011- 17-2-0043
OpenAlex ID:
G4154841007
Diverse viral cas genes antagonize CRISPR immunity
2024
·
Mark A. Katz
, Edith M. Sawyer
, et al.
·
Nature
·
32
PDF
Lipid-coated mesoporous silica nanoparticles for anti-viral applications via delivery of CRISPR-Cas9 ribonucleoproteins
2023
·
Annette E. LaBauve
, Edwin A. Saada
, et al.
·
Scientific Reports
·
45
PDF
Translation-dependent downregulation of Cas12a mRNA by an anti-CRISPR protein
2022
·
Nicole D. Marino
, Alexander Talaie
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
12
PDF
Lack of Cas13a inhibition by anti-CRISPR proteins from Leptotrichia prophages
2022
·
Matthew C. Johnson
, Logan T. Hille
, et al.
·
Molecular Cell
·
13
PDF
Immunocompromised Cas9 transgenic mice for rapid in vivo assessment of host factors involved in highly pathogenic virus infection
2021
·
Nicole Collette
, Pragyesh Dhungel
, et al.
·
Molecular Therapy — Methods & Clinical Development
·
3
PDF
Engineering improved Cas13 effectors for targeted post-transcriptional regulation of gene expression
2021
·
Emeric J Charles
, Shin Eui Kim
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
32
PDF
OUP accepted manuscript
2021
·
Shrutee Jakhanwal
, Brady F Cress
, et al.
·
Nucleic Acids Research
·
18
Controlling and enhancing CRISPR systems
2020
·
Haridha Shivram
, Brady F. Cress
, et al.
·
Nature Chemical Biology
·
192
Discovery of multiple anti-CRISPRs highlights anti-defense gene clustering in mobile genetic elements
2020
·
Rafael Pinilla-Redondo
, Saadlee Shehreen
, et al.
·
Nature Communications
·
146
PDF
Author Correction: Broad-spectrum anti-CRISPR proteins facilitate horizontal gene transfer
2020
·
Caroline Mahendra
, Kathleen A. Christie
, et al.
·
Nature Microbiology
·
10
PDF
Machine learning predicts new anti-CRISPR proteins
2020
·
Simon Eitzinger
, Amina Asif
, et al.
·
Nucleic Acids Research
·
122
PDF
Anti-CRISPR protein applications: natural brakes for CRISPR-Cas technologies
2020
·
Nicole D. Marino
, Rafael Pinilla-Redondo
, et al.
·
Nature Methods
·
240
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes
2020
·
Kyle E. Watters
, Haridha Shivram
, et al.
·
Proceedings of the National Academy of Sciences
·
68
PDF
Pervasive functional translation of noncanonical human open reading frames
2020
·
Jin Chen
, Andreas-David Brunner
, et al.
·
Science
·
654
New candidates for regulated gene integrity revealed through precise mapping of integrative genetic elements
2020
·
Catherine M Mageeney
, Britney Y Lau
, et al.
·
Nucleic Acids Research
·
35
PDF
The promise and challenge of therapeutic genome editing
2020
·
Jennifer A. Doudna
·
Nature
·
1,145
Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a
2019
·
Gavin J Knott
, Brady F Cress
, et al.
·
eLife
·
55
Broad-spectrum enzymatic inhibition of CRISPR-Cas12a
2019
·
Gavin J. Knott
, Brittney W. Thornton
, et al.
·
Nature Structural & Molecular Biology
·
116
Ultrasensitive multi-species detection of CRISPR-Cas9 by a portable centrifugal microfluidic platform
2019
·
Christopher R. Phaneuf
, Kyle J. Seamon
, et al.
·
Analytical Methods
·
27
Temperature-Responsive Competitive Inhibition of CRISPR-Cas9
2018
·
Fuguo Jiang
, Jun-Jie Liu
, et al.
·
Molecular Cell
·
80
Discovery of widespread type I and type V CRISPR-Cas inhibitors
2018
·
Nicole D. Marino
, Jenny Y. Zhang
, et al.
·
Science
·
271
Mapping the Genetic Landscape of Human Cells
2018
·
Max A. Horlbeck
, Albert Xu
, et al.
·
Cell
·
316
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