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Hif1在调控肿瘤细胞脂代谢中的作用及分子机制

Amount: ¥750,000
Funding type: grant
Funder scheme: 面上项目
Start date: 2013-01-01
End date: 2017-12-31
Investigator: 华凤 张 (lead)
Institutions: University of Science and Technology of China, 中国科学技术大学
Subfield: Cancer Research
Funded outputs count: 10
Funder award ID: 31371429
OpenAlex ID: G4265734905
Polo-like kinase 1 coordinates biosynthesis during cell cycle progression by directly activating pentose phosphate pathway
2017 · Xiaoyu Ma, Lin Wang, et al. · Nature Communications · 143
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Menin enhances c-Myc-mediated transcription to promote cancer progression
2017 · Gongwei Wu, Mengqiu Yuan, et al. · Nature Communications · 71
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Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission
2017 · Lihua Wang, Tong Zhang, et al. · The EMBO Journal · 141
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CUE domain‐containing protein 2 promotes the Warburg effect and tumorigenesis
2017 · Xiuying Zhong, Shengya Tian, et al. · EMBO Reports · 27
Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress
2016 · De Huang, Tingting Li, et al. · Cell Research · 179
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Reprogramming of glucose, fatty acid and amino acid metabolism for cancer progression
2015 · Zhaoyong Li, Huafeng Zhang · Cellular and Molecular Life Sciences · 892
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions
2015 · Linchong Sun, Libing Song, et al. · Cell Research · 318
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miR‐290/371‐Mbd2‐Myc circuit regulates glycolytic metabolism to promote pluripotency
2015 · Yang Cao, Wen‐Ting Guo, et al. · The EMBO Journal · 96
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Hypoxia-inducible factor 1 and breast cancer metastasis
2015 · Zhao-ji Liu, Gregg L. Semenza, et al. · Journal of Zhejiang University SCIENCE B · 266
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Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1
2014 · Xiaoyu Ma, Chenchen Li, et al. · Nature Communications · 186
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