Improving bio-functions of polymer-based composites using hydrophilic aluminum silicate nanotubes
Description: The objective of this project was to prepare mechanically-flexible artificial bones, applicable to any bone-void shapes, with enhancing effect for bone regeneration through releasing inorganic ions such as calcium and silicate ions.Siloxane-containing calcium carbonate particles were embedded in poly(hydroxylalkanoate), and the resulting composites were shaped into a cotton-wool-like structure composed of ~10 um-fiber skeletons. The fibers were successfully coated with hydrophilic aluminum silicate nanotubes (imogolite).The materials could release calcium and silicate ions gradually, and showed an excellent protein adsorption ability and the healthy proliferation of osteoblast-like cells.
Amount: ¥4,030,000
Funding type: research
Funder scheme: Grant-in-Aid for Challenging Exploratory Research
Start date: 2013-04-01
End date: 2016-03-31
Investigator: Toshihiro Kasuga (lead)
Institution: Nagoya Institute of Technology
Funded outputs count: 12
Funder award ID: 25630282
OpenAlex ID: G4281444591